Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Xavier Carnec"'
Autor:
Mathieu Mateo, Stéphanie Reynard, Natalia Pietrosemoli, Emeline Perthame, Alexandra Journeaux, Kodie Noy, Clara Germain, Xavier Carnec, Caroline Picard, Virginie Borges-Cardoso, Jimmy Hortion, Hélène Lopez-Maestre, Pierrick Regnard, Lyne Fellmann, Audrey Vallve, Stéphane Barron, Ophélie Jourjon, Orianne Lacroix, Aurélie Duthey, Manon Dirheimer, Maïlys Daniau, Catherine Legras-Lachuer, Caroline Carbonnelle, Hervé Raoul, Frédéric Tangy, Sylvain Baize
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Lassa virus vaccination is impeded by the limited capacity of vaccine candidates to induce rapid protection. In this study, the authors found that a single shot of a measles-based Lassa vaccine protected nonhuman primates 16 or 8 days after vaccinati
Externí odkaz:
https://doaj.org/article/cf6be5bf89674509b73202e1f94537d5
Autor:
Mathieu Mateo, Jimmy Hortion, Emeline Perthame, Caroline Picard, Stéphanie Reynard, Alexandra Journeaux, Clara Germain, Xavier Carnec, Nicolas Baillet, Virginie Borges-Cardoso, Natalia Pietrosemoli, Audrey Vallve, Stéphane Barron, Ophélie Jourjon, Orianne Lacroix, Aurélie Duthey, Manon Dirheimer, Maïlys Daniau, Catherine Legras-Lachuer, Gregory Jouvion, Caroline Carbonnelle, Hervé Raoul, Sylvain Baize
Publikováno v:
Virulence, Vol 13, Iss 1, Pp 654-669 (2022)
The area of Lassa virus (LASV) circulation is expanding, with the emergence of highly pathogenic new LASV lineages. Benin recently became an endemic country for LASV and has seen the emergence of a new LASV lineage (VII). The first two outbreaks in 2
Externí odkaz:
https://doaj.org/article/c350a40e14234312b45ff573b2fd8f25
Autor:
Nicolas Baillet, Stéphanie Reynard, Emeline Perthame, Jimmy Hortion, Alexandra Journeaux, Mathieu Mateo, Xavier Carnec, Justine Schaeffer, Caroline Picard, Laura Barrot, Stéphane Barron, Audrey Vallve, Aurélie Duthey, Frédéric Jacquot, Cathy Boehringer, Grégory Jouvion, Natalia Pietrosemoli, Rachel Legendre, Marie-Agnès Dillies, Richard Allan, Catherine Legras-Lachuer, Caroline Carbonnelle, Hervé Raoul, Sylvain Baize
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-19 (2021)
Baillet et al. use the cynomolgus monkey model to model Lassa virus and associated Lassa fever (LF). They provide a full characterisation of LF pathogenesis with the aim of assisting the development of early diagnostic tools.
Externí odkaz:
https://doaj.org/article/97528d0810d148d594a62a4f23cbd59b
Autor:
Othmann Merabet, Natalia Pietrosemoli, Emeline Perthame, Jean Armengaud, Jean-Charles Gaillard, Virginie Borges-Cardoso, Maïlys Daniau, Catherine Legras-Lachuer, Xavier Carnec, Sylvain Baize
Publikováno v:
Viruses, Vol 14, Iss 3, p 652 (2022)
Lassa virus (LASV), an Old World arenavirus, is responsible for hemorrhagic fevers in western Africa. The privileged tropism of LASV for endothelial cells combined with a dysregulated inflammatory response are the main cause of the increase in vascul
Externí odkaz:
https://doaj.org/article/9230cc31eef24b1d9b66c53526d47979
Autor:
Ophélie Dejarnac, Mohamed Lamine Hafirassou, Maxime Chazal, Margaux Versapuech, Julien Gaillard, Manuel Perera-Lecoin, Claudia Umana-Diaz, Lucie Bonnet-Madin, Xavier Carnec, Jean-Yves Tinevez, Constance Delaugerre, Olivier Schwartz, Philippe Roingeard, Nolwenn Jouvenet, Clarisse Berlioz-Torrent, Laurent Meertens, Ali Amara
Publikováno v:
Cell Reports, Vol 23, Iss 6, Pp 1779-1793 (2018)
Summary: Dengue virus (DENV) is a major human pathogen causing millions of infections yearly. Despite intensive investigations, a DENV receptor that directly participates in virus internalization has not yet been characterized. Here, we report that t
Externí odkaz:
https://doaj.org/article/e9342707f6bf4b168845c0906c68bef1
Autor:
Justine Schaeffer, Xavier Carnec, Stéphanie Reynard, Mathieu Mateo, Caroline Picard, Natalia Pietrosemoli, Marie-Agnès Dillies, Sylvain Baize
Publikováno v:
PLoS Pathogens, Vol 14, Iss 11, p e1007430 (2018)
Lassa virus (LASV) is responsible for a viral hemorrhagic fever in humans and the death of 3,000 to 5,000 people every year. The immune response to LASV is poorly understood, but type I interferon (IFN-I) and T-cell responses appear to be critical fo
Externí odkaz:
https://doaj.org/article/b4064dfc3c44436fac97cee19e6c228a
Autor:
Nicolas Baillet, Sophie Krieger, Xavier Carnec, Mathieu Mateo, Alexandra Journeaux, Othmann Merabet, Valérie Caro, Frédéric Tangy, Pierre-Olivier Vidalain, Sylvain Baize
Publikováno v:
Viruses, Vol 12, Iss 1, p 49 (2019)
Lassa virus (LASV) and Mopeia virus (MOPV) are two closely related, rodent-born mammarenaviruses. LASV is the causative agent of Lassa fever, a deadly hemorrhagic fever endemic in West Africa, whereas MOPV is non-pathogenic in humans. The Z matrix pr
Externí odkaz:
https://doaj.org/article/a6ea2978badb41048f265ec80dd35e80
Autor:
Justine Schaeffer, Stéphanie Reynard, Xavier Carnec, Natalia Pietrosemoli, Marie-Agnès Dillies, Sylvain Baize
Publikováno v:
Viruses, Vol 11, Iss 3, p 287 (2019)
Lassa virus (LASV) causes a viral haemorrhagic fever in humans and is a major public health concern in West Africa. An efficient immune response to LASV appears to rely on type I interferon (IFN-I) production and T-cell activation. We evaluated the r
Externí odkaz:
https://doaj.org/article/801bd0bfddfe4d18988332ea3b8d008d
Publikováno v:
Viruses, Vol 6, Iss 1, Pp 69-88 (2013)
Flaviviruses enter host cells by endocytosis initiated when the virus particles interact with cell surface receptors. The current model suggests that flaviviruses use at least two different sets of molecules for infectious entry: attachment factors t
Externí odkaz:
https://doaj.org/article/1e0b4ac4d9f143e89df9e45dc2158fc3
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 1, p e2637 (2014)
The pathogenesis of Lassa fever (LF), a hemorrhagic fever endemic to West Africa, remains unclear. We previously compared Lassa virus (LASV) with its genetically close, but nonpathogenic homolog Mopeia virus (MOPV) and demonstrated that the strong ac
Externí odkaz:
https://doaj.org/article/84caaa12130f4ac78278b9b630b719c5