Výsledky vyhledávání - "Xavier Cabana-Puig"

Akademický článek

Nlrp12 deficiency alters gut microbiota and ameliorates Faslpr-mediated systemic autoimmunity in male mice

Autor: Leila Abdelhamid, Jiangdi Mao, Xavier Cabana-Puig, Jing Zhu, Brianna K. Swartwout, Michael R. Edwards, James C. Testerman, Jacquelyn S. Michaelis, Irving Coy Allen, S. Ansar Ahmed, Xin M. Luo

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

NLRP12 has dual roles in shaping inflammation. We hypothesized that NLRP12 would modulate myeloid cells and T cell function to control systemic autoimmunity. Contrary to our hypothesis, the deficiency of Nlrp12 in autoimmune-prone B6.Faslpr/lpr mice

Externí odkaz: https://doaj.org/article/dd382a1d80b7478a870adf2346572e6d

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Akademický článek

1301 Lactobacillus spp. act in synergy to attenuate splenomegaly and lymphadenopathy in lupus- prone MRL/lpr mice

Autor: Zhuang Wang, Jing Zhu, Christopher M Reilly, Xavier Cabana-Puig, Qinghui Mu, Ran Lu, Brianna Swartwout, Leila Abdelhamid, Meeta Prakash, Thomas E Cecere, Sabrina Callaway, Sha Sun, S Ansar Ahmed, Xin M Luo

Publikováno v: Lupus Science and Medicine, Vol 9, Iss Suppl 3 (2022)

Externí odkaz: https://doaj.org/article/f2f4672125d043cea13be9e741e6f947

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Akademický článek

Lactobacillus spp. act in synergy to attenuate splenomegaly and lymphadenopathy in lupus-prone MRL/lpr mice

Autor: Xavier Cabana-Puig, Qinghui Mu, Ran Lu, Brianna Swartwout, Leila Abdelhamid, Jing Zhu, Meeta Prakash, Thomas E. Cecere, Zhuang Wang, Sabrina Callaway, Sha Sun, Christopher M. Reilly, S. Ansar Ahmed, Xin M. Luo

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

Commensal bacteria and the immune system have a close and strong relationship that maintains a balance to control inflammation. Alterations of the microbiota, known as dysbiosis, can direct reactivity to self-antigens not only in the intestinal mucos

Externí odkaz: https://doaj.org/article/d616c05d09714ae697accf2231edb1e4

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Akademický článek

Pregnancy and lactation interfere with the response of autoimmunity to modulation of gut microbiota

Autor: Qinghui Mu, Xavier Cabana-Puig, Jiangdi Mao, Brianna Swartwout, Leila Abdelhamid, Thomas E. Cecere, Haifeng Wang, Christopher M. Reilly, Xin M. Luo

Publikováno v: Microbiome, Vol 7, Iss 1, Pp 1-13 (2019)

Abstract Background Dysbiosis of gut microbiota exists in the pathogenesis of many autoimmune diseases, including systemic lupus erythematosus (lupus). Lupus patients who experienced pregnancy usually had more severe disease flares post-delivery. How

Externí odkaz: https://doaj.org/article/cb133b20f64f4238b68a2faa5951e0f0

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Akademický článek

Quaternary Ammonium Compound Disinfectants Reduce Lupus-Associated Splenomegaly by Targeting Neutrophil Migration and T-Cell Fate

Autor: Leila Abdelhamid, Xavier Cabana-Puig, Qinghui Mu, Maryam Moarefian, Brianna Swartwout, Kristin Eden, Prerna Das, Ryan P. Seguin, Libin Xu, Sarah Lowen, Mital Lavani, Terry C. Hrubec, Caroline N. Jones, Xin M. Luo

Publikováno v: Frontiers in Immunology, Vol 11 (2020)

Hypersensitivity reactions and immune dysregulation have been reported with the use of quaternary ammonium compound disinfectants (QACs). We hypothesized that QAC exposure would exacerbate autoimmunity associated with systemic lupus erythematosus (lu

Externí odkaz: https://doaj.org/article/7ddad3130caf4113969e7361622e699f

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Akademický článek

Retinoic Acid Exerts Disease Stage-Dependent Effects on Pristane-Induced Lupus

Autor: Leila Abdelhamid, Xavier Cabana-Puig, Brianna Swartwout, Jiyoung Lee, Song Li, Sha Sun, Yaqi Li, A. Catharine Ross, Thomas E. Cecere, Tanya LeRoith, Stephen R. Werre, Haifeng Wang, Christopher M. Reilly, Xin M. Luo

Publikováno v: Frontiers in Immunology, Vol 11 (2020)

We previously showed that all-trans-retinoic acid (tRA), an active metabolite of vitamin A, exacerbated pre-existing autoimmunity in lupus; however, its effects before the development of autoimmunity are unknown. Here, using a pristane-induced model,

Externí odkaz: https://doaj.org/article/073fa686b8ea48038e207a55a9441bec

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