Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Xavier Buol"'
Autor:
Xavier Buol, Koen Robeyns, Camila Caro Garrido, Nikolay Tumanov, Laurent Collard, Johan Wouters, Tom Leyssens
Publikováno v:
Pharmaceutics, Vol 12, Iss 7, p 653 (2020)
In this work, we are the first to identify thirteen cocrystals of Nefiracetam, a poor water-soluble nootropic compound. Three of which were obtained with the biocompatible cocrystallization agents citric acid, oxalic acid, and zinc chloride. These la
Externí odkaz:
https://doaj.org/article/aa29a5f9ed88451f91e54de5f56b9475
Autor:
Nikolay Tumanov, Johan Wouters, Xavier Buol, Tom Leyssens, Laurent Collard, Camila Caro Garrido, Koen Robeyns
Publikováno v:
Crystal Growth & Design, Vol. 20, no.12, p. 7979-7988 (2020)
In this paper, we identified a cocrystal conglomerate of mandelic acid using a drug compound as a coformer. We then developed a chiral resolution process based on preferential cocrystallization. Several versions of such a process were explored and op
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8430a31fa3f46deef47832a271c3ed22
https://doi.org/10.1021/acs.cgd.0c01236
https://doi.org/10.1021/acs.cgd.0c01236
Publikováno v:
Journal of Pharmaceutical Sciences, Vol. 108, no. 11, p. 3616-3622 (2019)
In this work, 3 hitherto unidentified solid state forms of the nootropic drug Nefiracetam are identified: a monohydrate and 2 polymorphic phases of the anhydrate. These new forms were investigated from a structural and thermodynamic point of view to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::004461f21eabd2acc0778f89c7b56be0
https://doi.org/10.1016/j.xphs.2019.07.010
https://doi.org/10.1016/j.xphs.2019.07.010
Publikováno v:
Journal of Pharmaceutical Sciences, Vol. 109, no.12, p. 3645-3652 (2020)
Four forms of a salt combining two antitubercular drugs, clofazimine and 4-aminosalicylic acid, are reported and the crystal structure of two of these forms are described. TG/DSC analysis of all four forms demonstrate an increase in the temperature a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3340f417896178debc1b6e6d1413382
https://pubmed.ncbi.nlm.nih.gov/33455726
https://pubmed.ncbi.nlm.nih.gov/33455726
Publikováno v:
The Journal of Physical Chemistry C. 120:10001-10008
The crystal structures and optical properties of (E)-2-methoxy-6-(pyridin-3-yliminomethyl)phenol (1), a N-salicylidene-3-aminopyridine, and its 2:1 dimorphic cocrystals with fumaric acid (2 and 3) and succinic acid (4 and 5) were studied at solid sta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66ad434fc5942d4f5b51f79e0424ec84
https://doi.org/10.1021/acs.jpcc.6b02734
https://doi.org/10.1021/acs.jpcc.6b02734