Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Xavier Bisteau"'
Autor:
Sabine Paternot, Eric Raspé, Clément Meiller, Maxime Tarabichi, Jean‐Baptiste Assié, Frederick Libert, Myriam Remmelink, Xavier Bisteau, Patrick Pauwels, Yuna Blum, Nolwenn Le Stang, Séverine Tabone‐Eglinger, Françoise Galateau‐Sallé, Christophe Blanquart, Jan P. Van Meerbeeck, Thierry Berghmans, Didier Jean, Pierre P. Roger
Publikováno v:
Molecular Oncology, Vol 18, Iss 4, Pp 866-894 (2024)
Malignant pleural mesothelioma (MPM) is an aggressive cancer with limited therapeutic options. We evaluated the impact of CDK4/6 inhibition by palbociclib in 28 MPM cell lines including 19 patient‐derived ones, using various approaches including RN
Externí odkaz:
https://doaj.org/article/72b5f65e65c1467eb0155ad0c9eabfb4
Autor:
Abeer Kaafarani, Romain Darche-Gabinaud, Xavier Bisteau, Virginie Imbault, Valérie Wittamer, Marc Parmentier, Isabelle Pirson
Publikováno v:
Cells, Vol 12, Iss 22, p 2625 (2023)
The Super-Conserved Receptors Expressed in the Brain (SREBs) form a subfamily of orphan G protein-coupled receptors, highly conserved in evolution and characterized by a predominant expression in the brain. The signaling pathways activated by these r
Externí odkaz:
https://doaj.org/article/75110abea3fc4ec1b16687b41b3633fa
Autor:
Matthew R Dewhurst, Jin Rong Ow, Gözde Zafer, Noémi K M van Hul, Heike Wollmann, Xavier Bisteau, David Brough, Hyungwon Choi, Philipp Kaldis
Publikováno v:
PLoS Genetics, Vol 16, Iss 11, p e1009084 (2020)
The liver possesses a remarkable regenerative capacity based partly on the ability of hepatocytes to re-enter the cell cycle and divide to replace damaged cells. This capability is substantially reduced upon chronic damage, but it is not clear if thi
Externí odkaz:
https://doaj.org/article/3ed9f26de6f54ab09444430784a848ca
Autor:
Juan Alfonso Redondo, Romain Bibes, Alizée Vercauteren Drubbel, Benjamin Dassy, Xavier Bisteau, Eleonore Maury, Benjamin Beck
Publikováno v:
Biology, Vol 10, Iss 4, p 266 (2021)
Esophageal squamous cell carcinoma (eSCC) accounts for more than 85% cases of esophageal cancer worldwide and the 5-year survival rate associated with metastatic eSCC is poor. This low survival rate is the consequence of a complex mechanism of resist
Externí odkaz:
https://doaj.org/article/ae05c446505b48e48339d4aaee63cbda
Autor:
M Kasim Diril, Xavier Bisteau, Mayumi Kitagawa, Matias J Caldez, Sheena Wee, Jayantha Gunaratne, Sang Hyun Lee, Philipp Kaldis
Publikováno v:
PLoS Genetics, Vol 12, Iss 9, p e1006310 (2016)
The Greatwall kinase/Mastl is an essential gene that indirectly inhibits the phosphatase activity toward mitotic Cdk1 substrates. Here we show that although Mastl knockout (MastlNULL) MEFs enter mitosis, they progress through mitosis without completi
Externí odkaz:
https://doaj.org/article/8719bcbfa88d457088ca4a629cfc0cb2
Autor:
Senthil Raja Jayapal, Chelsia Qiuxia Wang, Xavier Bisteau, Matias J. Caldez, Shuhui Lim, Vinay Tergaonkar, Motomi Osato, Philipp Kaldis
Publikováno v:
Haematologica, Vol 100, Iss 4 (2015)
Mouse knockouts of Cdk2 and Cdk4 are individually viable whereas the double knockouts are embryonic lethal due to heart defects, and this precludes the investigation of their overlapping roles in definitive hematopoiesis. Here we use a conditional kn
Externí odkaz:
https://doaj.org/article/926090a93b1f4415806bd2e65b8520b7
Autor:
Xavier Bisteau, Sabine Paternot, Bianca Colleoni, Karin Ecker, Katia Coulonval, Philippe De Groote, Wim Declercq, Ludger Hengst, Pierre P Roger
Publikováno v:
PLoS Genetics, Vol 9, Iss 5, p e1003546 (2013)
Cell cycle progression, including genome duplication, is orchestrated by cyclin-dependent kinases (CDKs). CDK activation depends on phosphorylation of their T-loop by a CDK-activating kinase (CAK). In animals, the only known CAK for CDK2 and CDK1 is
Externí odkaz:
https://doaj.org/article/b86c2887456640dd98e423b1f1538418
Autor:
Mireia Rovira, Magali Miserocchi, Alice Montanari, Latifa Hammou, Laura Chomette, Jennifer Pozo, Virginie Imbault, Xavier Bisteau, Valérie Wittamer
Publikováno v:
Developmental Dynamics. 252
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4779729cbd30115efcf0bda9f264f3a0
https://doi.org/10.1002/dvdy.580
https://doi.org/10.1002/dvdy.580
Autor:
null Sabine Paternot, null Eric Raspé, null Clément Meiller, null Maxime Tarabichi, null Jean‐Baptiste Assié, null Frederick Libert, null Myriam Remmelink, null Xavier Bisteau, null Patrick Pauwels, null Yuna Blum, null Nolwenn Le Stang, null Séverine Tabone‐Eglinger, null Françoise Galateau‐Sallé, null Christophe Blanquart, null Jan P. Van Meerbeeck, null Thierry Berghmans, null Didier Jean, null Pierre P. Roger
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6932f8a919a7a1350efb1a248ea44da
https://doi.org/10.1002/1878-0261.13351/v2/response1
https://doi.org/10.1002/1878-0261.13351/v2/response1
Zebrafish Galectin 3 binding protein is the target antigen of the microglial 4C4 monoclonal antibody
Autor:
Mireia Rovira, Magali Miserocchi, Alice Montanari, Latifa Hammou, Laura Chomette, Jennifer Pozo, Virginie Imbault, Xavier Bisteau, Valérie Wittamer
Publikováno v:
Developmental dynamics : an official publication of the American Association of AnatomistsREFERENCES.
Two decades ago, the fish-specific monoclonal antibody 4C4 was found to be highly reactive to zebrafish microglia, the macrophages of the central nervous system. This has resulted in 4C4 being widely used, in combination with available fluorescent tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b60298635d15e55d7ecc1458c48924f
https://pubmed.ncbi.nlm.nih.gov/36285351
https://pubmed.ncbi.nlm.nih.gov/36285351