Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Xavier Alexander Lee"'
Publikováno v:
EBioMedicine, Vol 77, Iss , Pp 103877- (2022)
Externí odkaz:
https://doaj.org/article/1636239a48ce456d83ec9a50744c1361
Autor:
Patrick B. Meagher, Xavier Alexander Lee, Joseph Lee, Aylin Visram, Mark K. Friedberg, Kim A. Connelly
Publikováno v:
Cells, Vol 10, Iss 4, p 770 (2021)
Cardiac fibrosis is a common finding that is associated with the progression of heart failure (HF) and impacts all chambers of the heart. Despite intense research, the treatment of HF has primarily focused upon strategies to prevent cardiomyocyte rem
Externí odkaz:
https://doaj.org/article/242cc3979b244603957c5b48a5b6161a
Autor:
Christopher M. Yip, Shin-Haw Lee, Anthony O. Gramolini, Neal I. Callaghan, Mansoor Husain, Sina Hadipour-Lakmehsari, Amine Driouchi, Craig A. Simmons, Xavier Alexander Lee, M. Ahsan Siraj
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-10 (2020)
Communications Biology
Communications Biology
Primary adult cardiomyocyte (aCM) represent the mature form of myocytes found in the adult heart. However, culture of aCMs in particular is challenged by poor survival and loss of phenotype, rendering extended in vitro experiments unfeasible. Here, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5211222742dc90446fc6d4def52e26b8
http://link.springer.com/article/10.1038/s42003-020-0946-9
http://link.springer.com/article/10.1038/s42003-020-0946-9
Autor:
Kim A. Connelly, Mark K. Friedberg, Patrick Meagher, Joseph Lee, Aylin Visram, Xavier Alexander Lee
Publikováno v:
Cells
Cells, Vol 10, Iss 770, p 770 (2021)
Cells, Vol 10, Iss 770, p 770 (2021)
Cardiac fibrosis is a common finding that is associated with the progression of heart failure (HF) and impacts all chambers of the heart. Despite intense research, the treatment of HF has primarily focused upon strategies to prevent cardiomyocyte rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::327fcf164235dff36e55831510337b76
http://europepmc.org/articles/PMC8066890
http://europepmc.org/articles/PMC8066890
Autor:
Kim A. Connelly, Robert A. Civitarese, Antoinette Bugyei-Twum, Patrick Meagher, Jean-Francois Desjardins, Hari Kosanam, Howard Leong-Poi, Golam Kabir, Aylin Visram, Xavier Alexander Lee, Yanling Zhang, Mark Gordon, Andrew Advani
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0252711 (2021)
PLoS ONE
PLoS ONE
Background Patients with diabetes are at a high risk for developing cardiac dysfunction in the absence of coronary artery disease or hypertension, a condition known as diabetic cardiomyopathy. Contributing to heart failure is the presence of diabetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5656f764a05d73163f1637b197e0d50e
https://doaj.org/article/bf5e3aaf8bc74d9d816ad1580ad73504
https://doaj.org/article/bf5e3aaf8bc74d9d816ad1580ad73504
Publikováno v:
iScience, Vol 23, Iss 8, Pp 101350-(2020)
iScience
iScience
Summary A major unresolved challenge in cell-based regenerative medicine is the absence of non-invasive technologies for tracking cell fate in deep tissue and with high spatial resolution over an extended interval. MRI is highly suited for this task,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4db6939cf6ce41d6707f077be29d484
http://www.sciencedirect.com/science/article/pii/S258900422030537X
http://www.sciencedirect.com/science/article/pii/S258900422030537X
Publikováno v:
The Journal of Physiology. 600:709-710
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10ed69b1e9c8f56117619a0c97bc091c
https://doi.org/10.1113/jp281655
https://doi.org/10.1113/jp281655
Publikováno v:
The Journal of Physiology. 598:1807-1808
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ec4aed2ed310970d5688e2636f7778a
https://doi.org/10.1113/jp279558
https://doi.org/10.1113/jp279558
Autor:
Amine Driouchi, Sina Hadipour-Lakmehsari, Anthony O. Gramolini, Christopher M. Yip, Mansoor Husain, Neal I. Callaghan, Shin-Haw Lee, Craig A. Simmons, Xavier Alexander Lee, M. Ahsan Siraj
Primary adult cardiomyocyte (aCM) culture is challenged by poor survival and loss of phenotype, rendering extendedin vitroexperiments unfeasible. Here, we establish murine aCM culture methods that enhance survival and maintain sarcomeric structure an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e67b8e26acb226de0150d88e1a80d1e
Publikováno v:
The Journal of Physiology
Key points This paper describes a novel model that allows exploration of matrix‐induced cardiomyocyte adaptations independent of the passive effect of matrix rigidity on cardiomyocyte function.Detachment of adult cardiomyocytes from the matrix enab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3712b30940b1d05e293cf397bbe7278a
https://pubmed.ncbi.nlm.nih.gov/28485491
https://pubmed.ncbi.nlm.nih.gov/28485491