Synthesis of 3,5-Diarylisoxazole Derivatives and Evaluation of in vitro Trypanocidal Activity

Autor: Souza,Aline A. N. de, Xavier,Viviane F., Coelho,Gleicekelly S., Sales Junior,Policarpo A., Romanha,Alvaro J., Murta,Silvane M. F., Carneiro,Claudia M., Taylor,Jason G.

Publikováno v: Journal of the Brazilian Chemical Society v.29 n.2 2018
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ

Chagas disease is included in the neglected tropical diseases list and is endemic to 21 Latin American countries. The two drugs currently available for treating Chagas disease are nifurtimox and benznidazole and both result in many significant side e

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