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Autor:
Ken'ichi Imanishi, Xao-Jie Yan, Junji Yagi, Wakae Fujimaki, Takehiko Uchiyama, Hidehito Kato, Tohru Miyoshi-Akiyama, Kyuhei Tomonari
Publikováno v:
Microbiology and immunology. 41(4)
We previously reported that Yersinia pseudotuberculosis-derived mitogen (YPM) acts as a superantigen to human T cells. In this study, we assessed the superantigenicity and toxicity of YPM using murine experimental models. YPM activated T cells to pro