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Background: NLRP3-driven inflammatory responses by circulating and lung-resident monocytes are critical drivers of asthma pathogenesis. Autophagy restrains NLRP3-induced monocyte activation in asthma models. Yet, the effects of autophagy and its mast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::18499384d445b3506fd4f009a99a4c2e
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3003174
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3003174
Pioneering studies on tumor and immune cell interactions have highlighted immune checkpoint inhibitors (ICIs) as revolutionizing interventions for the management of NSCLC, typically combined with traditional MTD chemotherapies, which usually lead to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::04fe5b4bd9b6b38dedf8a3ef6dd66590
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3077126
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3077126
An amendment to this paper has been published and can be accessed via a link at the top of the paper. © 2020, Springer Nature Limited.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::113b6ad33871bc1a790f6000c3bb7d52
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:2997124
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:2997124
Autor:
Theofani, E. Xanthou, G.
Autophagy is a major self-degradative process through which cytoplasmic material, including damaged organelles and proteins, are delivered and degraded in the lysosome. Autophagy represents a dynamic recycling system that produces new building blocks
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::3581f4d465fc3e8e599c0a0693bcafca
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:2980764
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:2980764
During early post-natal life, neonates must adjust to the transition from the sheltered intra-uterine environment to the microbe-laden external world, wherein they encounter a constellation of antigens and the colonization by the microbiome. At this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::25c9b61034a662ab177c6545aa202cab
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3104841
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3104841
Autor:
Chaker, A.M., Zissler, U.M., Poulos, N., Wagenmann, M., Bas, M., Gürth, F., Xanthou, G., Schmidt-Weber, C.
Background: Allergic upper airway disease involves pro-inflammatory type-2 cytokines such as IL-5 and regulatory tissue repair mediators, in particular transforming growth factor (TGF)-β1. The TGF-β-superfamily member activin-A displays multiple bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8dfadf230b52d4085d8b4b9ef7a02ee5
Autor:
Edwards, MR, Saglani, S, Schwarze, J, Skevaki, C, Smith, JA, Ainsworth, B, Almond, M, Andreakos, E, Belvisi, MG, Chung, KF, Cookson, W, Cullinan, P, Hawrylowicz, C, Lommatzsch, M, Jackson, DJ, Lutter, R, Marsland, B, Moffatt, M, Thomas, M, Virchow, JC, Xanthou, G, Edwards, J, Walker, S, Johnston, SL
Asthma is a heterogeneous, complex disease with clinical phenotypes that incorporate persistent symptoms and acute exacerbations. It affects many millions of Europeans throughout their education and working lives and puts a heavy cost on European pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::296c5d5555c96a16efc58f621362f0f1
https://eprints.soton.ac.uk/408600/
https://eprints.soton.ac.uk/408600/
Asthma is a heterogeneous, complex disease with clinical phenotypes that incorporate persistent symptoms and acute exacerbations. It affects many millions of Europeans throughout their education and working lives and puts a heavy cost on European pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::cf5722e16571aef58f5054260d3a9b96
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3108695
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3108695
Approximately 90% of alpha-synuclein (α-Synuclein) deposited in Lewy bodies is phosphorylated at serine 129 suggesting that the accumulation of phosphorylated α-Synuclein is critical in the pathogenesis of Parkinson's disease. However, in vivo expe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::516f8b30a93bb2ca75be9d93109afca2
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3056622
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3056622