Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Xanthi I Couroucli"'
Autor:
Krithika Lingappan, Chandra Srinivasan, Weiwu Jiang, Lihua Wang, Xanthi I Couroucli, Bhagavatula Moorthy
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101581 (2014)
Exposure to high concentration of oxygen (hyperoxia) leads to lung injury in experimental animal models and plays a role in the pathogenesis of diseases such as Acute Respiratory Distress Syndrome (ARDS) and Bronchopulmonary dysplasia (BPD) in humans
Externí odkaz:
https://doaj.org/article/f7f5f248e0ba4041bc2e30f8b09134f3
Autor:
Guo-Dong Zhou, Huiping Zhu, Tracie D Phillips, Jianbo Wang, Shi-Zhou Wang, Fen Wang, Brad A Amendt, Xanthi I Couroucli, Kirby C Donnelly, Bhagavatula Moorthy
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26589 (2011)
Many carcinogenic polycyclic aromatic hydrocarbons (PAHs) and their metabolites can bind covalently to DNA. Carcinogen-DNA adducts may lead to mutations in critical genes, eventually leading to cancer. In this study we report that fish oil (FO) block
Externí odkaz:
https://doaj.org/article/7fb7f202246f4c75832d109a31547dfe
Publikováno v:
Expert Opin Drug Metab Toxicol
INTRODUCTION: Hyperoxic lung injury is a condition that can occur in patients in need of supplemental oxygen, such as premature infants with bronchopulmonary dysplasia or adults with acute respiratory distress syndrome. Cytochrome P450 (CYP) enzymes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0a0c42b459de753bbb1894a492785b6
https://doi.org/10.1080/17425255.2021.1853705
https://doi.org/10.1080/17425255.2021.1853705
Autor:
Paramahamsa Maturu, Yanhong Wei-Liang, Weiwu Jiang, Lihua Wang, Krithika Lingappan, Roberto Barrios, Yao Liang, Bhagavatula Moorthy, Xanthi I Couroucli
Publikováno v:
Toxicol Sci
Prolonged hyperoxia contributes to bronchopulmonary dysplasia (BPD) in preterm infants. β-Naphthoflavone (BNF) is a potent inducer of cytochrome P450 (CYP)1A enzymes, which have been implicated in hyperoxic injuries in adult mice. In this investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fefa520c0a57d03a4426488b8d392dfa
https://europepmc.org/articles/PMC9216002/
https://europepmc.org/articles/PMC9216002/
Autor:
Guodong Zhou, Nagireddy Putluri, Chun Chu, Vasanta Putluri, Rachel Stading, Bhagavatula Moorthy, Krithika Lingappan, Rebecca Burke, Xanthi I. Couroucli
Publikováno v:
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2021 (2021)
Oxidative Medicine and Cellular Longevity, Vol 2021 (2021)
Supplemental oxygen administration is frequently used in premature infants and adults with pulmonary insufficiency. NADPH quinone oxidoreductase (NQO1) protects cells from oxidative injury by decreasing reactive oxygen species (ROS). In this investig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7505d3bda10b9880b19d52e9ab8f7613
http://europepmc.org/articles/PMC8536466
http://europepmc.org/articles/PMC8536466
Publikováno v:
C27. BRONCHOPULMONARY DYSPLASIA AND CONGENITAL LUNG LESIONS I.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29ea3c56449c4cb15f57c1a0bba5a594
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a4652
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a4652
Publikováno v:
A51. PEDIATRIC CRITICAL CARE INCLUDING INTERVENTIONAL BRONCHOSCOPY.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57a90f9aa4742fc9c759792bc9c30a62
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a1944
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a1944
Publikováno v:
Curr Opin Toxicol
Cytochrome P4501A (CYP1A) enzymes play important roles in xenobiotic and endobiotic metabolism. Due to uncoupling reactions during the enzymatic cycle, CYP1A enzymes can release reactive oxidative species (ROS) in the form of superoxide radical, hydr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e5fb8e0478eea67e72efcf144457194
https://europepmc.org/articles/PMC7709944/
https://europepmc.org/articles/PMC7709944/
Autor:
Xanthi I. Couroucli, Boura'a Bou Aram, Lihua Wang, Weiwu Jiang, Alex Veith, Krithika Lingappan, Guodong Zhou, Colin R. Jefcoate, Bhagavatula Moorthy
Publikováno v:
Toxicological Sciences. 165:462-474
Supplemental oxygen is a life-saving intervention administered to individuals suffering from respiratory distress, including adults with acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). Despite the clinical benefit, supplementa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d926be1f439c59bdba6366f42ecdd6b
https://doi.org/10.1093/toxsci/kfy154
https://doi.org/10.1093/toxsci/kfy154
Autor:
Xanthi I. Couroucli
Publikováno v:
Curr Opin Toxicol
Oxygen supplementation has been used as a part of respiratory care for preterm and term newborns since the beginning of 19th century. Although oxygen administration can be life-saving, reactive oxygen species (ROS) and reactive nitrogen species (RNS)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b36ec60945f2753268f77b6193f6415
https://doi.org/10.1016/j.cotox.2017.11.008
https://doi.org/10.1016/j.cotox.2017.11.008