Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Xandor M. Spijkers"'
Autor:
Nienke R. Wevers, Arya Lekshmi Nair, Tania M. Fowke, Maria Pontier, Dhanesh G. Kasi, Xandor M. Spijkers, Charlie Hallard, Gwenaëlle Rabussier, Remko van Vught, Paul Vulto, Helga E. de Vries, Henriëtte L. Lanz
Publikováno v:
Fluids and Barriers of the CNS, Vol 18, Iss 1, Pp 1-18 (2021)
Abstract Background In ischemic stroke, the function of the cerebral vasculature is impaired. This vascular structure is formed by the so-called neurovascular unit (NVU). A better understanding of the mechanisms involved in NVU dysfunction and recove
Externí odkaz:
https://doaj.org/article/b8e062e78c674526a9e9f6fc8baa3af9
Autor:
Xandor M. Spijkers, Svetlana Pasteuning-Vuhman, Jennifa C. Dorleijn, Paul Vulto, Nienke R. Wevers, R. Jeroen Pasterkamp
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract We report a method to generate a 3D motor neuron model with segregated and directed axonal outgrowth. iPSC-derived motor neurons are cultured in extracellular matrix gel in a microfluidic platform. Neurons extend their axons into an adjacent
Externí odkaz:
https://doaj.org/article/d11774b7f2654065b86858fe12f68e23
Autor:
Xandor M Spijkers, Rianne de Jongh, R. Jeroen Pasterkamp, Svetlana Pasteuning-Vuhman, Paul Vulto
Publikováno v:
Journal of Neurochemistry. 157:393-412
Amyotrophic lateral sclerosis (ALS) is a fatal and progressive neurodegenerative disease affecting upper and lower motor neurons with no cure available. Clinical and animal studies reveal that the neuromuscular junction (NMJ), a synaptic connection b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1423dcd3dd37c922de842e98ac6a5243
https://doi.org/10.1111/jnc.15289
https://doi.org/10.1111/jnc.15289
Autor:
Xandor M Spijkers, R. Jeroen Pasterkamp, Svetlana Pasteuning-Vuhman, Jennifa C Dorleijn, Paul Vulto, Nienke R. Wevers
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
We report a method to generate a 3D motor neuron model with segregated and directed axonal outgrowth. iPSC-derived motor neurons are cultured in extracellular matrix gel in a microfluidic platform. Neurons extend their axons into an adjacent layer of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4d0fa0d31bce3e1796ce0c97768010c
https://pubmed.ncbi.nlm.nih.gov/33483540
https://pubmed.ncbi.nlm.nih.gov/33483540
Autor:
Karlijn Wilschut, Nienke R. Wevers, Xandor M Spijkers, Sebastiaan Johannes Trietsch, Remko van Vught, John Lowman, Paul Vulto
Publikováno v:
Drug Metabolism and Pharmacokinetics. 34:S54
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1686ee4f05de45cd872599fd3831b06b
https://doi.org/10.1016/j.dmpk.2018.09.191
https://doi.org/10.1016/j.dmpk.2018.09.191
Autor:
Wevers, Nienke R.1,2 (AUTHOR) n.wevers@mimetas.com, Nair, Arya Lekshmi1,2 (AUTHOR), Fowke, Tania M.1 (AUTHOR), Pontier, Maria1 (AUTHOR), Kasi, Dhanesh G.1 (AUTHOR), Spijkers, Xandor M.1,3 (AUTHOR), Hallard, Charlie1 (AUTHOR), Rabussier, Gwenaëlle1,4 (AUTHOR), van Vught, Remko1 (AUTHOR), Vulto, Paul1 (AUTHOR), de Vries, Helga E.2 (AUTHOR), Lanz, Henriëtte L.1 (AUTHOR)
Publikováno v:
Fluids & Barriers of the CNS. 12/14/2021, Vol. 18 Issue 1, p1-18. 18p.
Autor:
Jongh, Rianne, Spijkers, Xandor M., Pasteuning‐Vuhman, Svetlana, Vulto, Paul, Pasterkamp, R. Jeroen
Publikováno v:
Journal of Neurochemistry; May2021, Vol. 157 Issue 3, p393-412, 20p