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pro vyhledávání: '"Xaio Ling"'
Autor:
Jordan S Leyton-Mange, Min-Young Jang, Stacey N Lynch, Robert W Mills, Xaio Ling, Patrick T Ellinor, David J Milan
Publikováno v:
Circulation. 130
Introduction: Long QT syndrome (LQTS) is caused by delayed ventricular repolarization and is a cause of sudden death. In a recent chemical screen with an in vivo zebrafish model of LQTS-type 2, we identified 2-methoxy-N-[4-methylphenyl] benzamide (2M
Autor:
Jordan S Leyton-Mange, Robert W Mills, Min-Young Jang, Xaio Ling, Patrick T Ellinor, David J Milan
Publikováno v:
Circulation. 130
Introduction: The lack of high quality predictive models for drug-induced QT prolongation continues to be a significant problem in pharmaceutical development. While human pluripotent stem cell derived-cardiomyocytes (hPSC-CMs) hold promise to be a va