Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Xabier L. Aranguren"'
Autor:
Pilar Montero-Calle, María Flandes-Iparraguirre, Bernd Kuebler, Begoña Arán, Eduardo Larequi, Ilazki Anaut, Giulia Coppiello, Xabier L. Aranguren, Anna Veiga, Maria Teresa Basurte Elorz, Manuel García de Yébenes, Juan J. Gavira, Felipe Prósper, Olalla Iglesias-García, Manuel M. Mazo Vega
Publikováno v:
Stem Cell Research, Vol 71, Iss , Pp 103189- (2023)
Transthyretin (TTR) amyloid cardiomyopathy (ATTR-CM) is a life-threatening disease caused by the abnormal production of misfolded TTR protein by liver cells, which is then released systemically. Its amyloid deposition in the heart is linked to cardia
Externí odkaz:
https://doaj.org/article/d9e76d653cf74761bd4fed055fcc36eb
Autor:
Marta Moya-Jódar, Asier Ullate-Agote, Paula Barlabé, Juan Roberto Rodríguez-Madoz, Gloria Abizanda, Carolina Barreda, Xonia Carvajal-Vergara, Amaia Vilas-Zornoza, Juan Pablo Romero, Leire Garate, Xabier Agirre, Giulia Coppiello, Felipe Prósper, Xabier L. Aranguren
Publikováno v:
Stem Cell Reports, Vol 18, Iss 1, Pp 64-80 (2023)
Summary: Naive human pluripotent stem cells (hPSCs) are defined as the in vitro counterpart of the human preimplantation embryo’s epiblast and are used as a model system to study developmental processes. In this study, we report the discovery and c
Externí odkaz:
https://doaj.org/article/5525088ab778485bae0f0d5d92dd1f1f
Autor:
Miriam Bobadilla Muñoz, Josune Orbe, Gloria Abizanda, Florencio J. D. Machado, Amaia Vilas, Asier Ullate-Agote, Leire Extramiana, Arantxa Baraibar Churio, Xabier L. Aranguren, Gloria Cantero, Neira Sáinz Amillo, José Antonio Rodríguez, Luis Ramos García, Juan Pablo Romero Riojas, Ainara Vallejo-Illarramendi, Carmen Paradas, Adolfo López de Munain, José Antonio Páramo, Felipe Prósper, Ana Pérez-Ruiz
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Aged muscles accumulate satellite cells with a striking decline response to damage. Although intrinsic defects in satellite cells themselves are the major contributors to aging-associated stem cell dysfunction, increasing evidence suggests that chang
Externí odkaz:
https://doaj.org/article/6f3b235d66ea48b0903667a7547e22f3
Generation of NKX2.5GFP Reporter Human iPSCs and Differentiation Into Functional Cardiac Fibroblasts
Autor:
Leyre López-Muneta, Javier Linares, Oscar Casis, Laura Martínez-Ibáñez, Arantxa González Miqueo, Jaione Bezunartea, Ana Maria Sanchez de la Nava, Mónica Gallego, María Eugenia Fernández-Santos, Juan Roberto Rodriguez-Madoz, Xabier L. Aranguren, Francisco Fernández-Avilés, José Carlos Segovia, Felipe Prósper, Xonia Carvajal-Vergara
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2022)
Direct cardiac reprogramming has emerged as an interesting approach for the treatment and regeneration of damaged hearts through the direct conversion of fibroblasts into cardiomyocytes or cardiovascular progenitors. However, in studies with human ce
Externí odkaz:
https://doaj.org/article/18096c79bf8a442fbff2dd48d63ad000
Autor:
Marta Moya-Jódar, Giulia Coppiello, Juan Roberto Rodríguez-Madoz, Gloria Abizanda, Paula Barlabé, Amaia Vilas-Zornoza, Asier Ullate-Agote, Chiara Luongo, Ernesto Rodríguez-Tobón, Sergio Navarro-Serna, Evelyne París-Oller, Maria Oficialdegui, Xonia Carvajal-Vergara, Laura Ordovás, Felipe Prósper, Francisco Alberto García-Vázquez, Xabier L. Aranguren
Publikováno v:
Animals, Vol 12, Iss 14, p 1829 (2022)
Each year, tens of thousands of people worldwide die of end-stage organ failure due to the limited availability of organs for use in transplantation. To meet this clinical demand, one of the last frontiers of regenerative medicine is the generation o
Externí odkaz:
https://doaj.org/article/008bc07603ad4bfbbc64171c81d1b08e
Autor:
Javier Linares, Leyre López-Muneta, Estibaliz Arellano-Viera, Purificación Ripalda-Cemboráin, Elena Iglesias, Gloria Abizanda, Xabier L. Aranguren, Felipe Prósper, Xonia Carvajal-Vergara
Publikováno v:
Stem Cell Research, Vol 33, Iss , Pp 125-129 (2018)
Islet-1 (Isl1) is a transcription factor essential for life expressed in specific cells with different developmental origins. We have generated iPSC lines from fibroblasts of the transgenic Ai6 x Isl1-Cre (Ai6IslCre) mouse. Here we describe the compl
Externí odkaz:
https://doaj.org/article/caba4b1a8fb64ca1b63c94bdd722c56a
Autor:
Gloria Abizanda, Leyre López-Muneta, Javier Linares, Luis I. Ramos, Arantxa Baraibar-Churio, Miriam Bobadilla, Elena Iglesias, Giulia Coppiello, Purificación Ripalda-Cemboráin, Xabier L. Aranguren, Felipe Prósper, Ana Pérez-Ruiz, Xonia Carvajal-Vergara
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 17, p 9126 (2021)
The success of cell therapy for the treatment of myocardial infarction depends on finding novel approaches that can substantially implement the engraftment of the transplanted cells. In order to enhance cell engraftment, most studies have focused on
Externí odkaz:
https://doaj.org/article/1713a04fddf54d668a9b5648c70ae38b
Autor:
Giulia Coppiello, Gloria Abizanda, Natalia Aguado, Elena Iglesias, Olalla Iglesias-Garcia, Antonio Lo Nigro, Felipe Prosper, Xabier L. Aranguren
Publikováno v:
Stem Cell Research, Vol 21, Iss C, Pp 47-50 (2017)
We generated a rat iPSC line called ATCi-rSD95 from transgenic Sprague-Dawley GFP fetal fibroblasts. Established ATCi-rSD95 cells present a normal karyotype, silencing of the transgenes and express pluripotency-associated markers. Additionally, ATCi-
Externí odkaz:
https://doaj.org/article/73eed17e5cc04da1821105c9d04d7bef
Autor:
Giulia Coppiello, Gloria Abizanda, Natalia Aguado, Elena Iglesias, Olalla Iglesias-Garcia, Antonio Lo Nigro, Felipe Prosper, Xabier L. Aranguren
Publikováno v:
Stem Cell Research, Vol 21, Iss C, Pp 40-43 (2017)
We generated two rat embryonic stem cell (ESC) lines: ATCe-SD7.8 from Sprague-Dawley strain and ATCe-WK1 from Wistar Kyoto strain. Cells were marked with enhanced green fluorescent protein (eGFP) by transduction with a lentiviral vector. Cells presen
Externí odkaz:
https://doaj.org/article/540e324bbd254cb2b37c1984b9942973
Autor:
Giulia Coppiello, Gloria Abizanda, Natalia Aguado, Elena Iglesias, Estibaliz Arellano-Viera, Juan R Rodriguez-Madoz, Xonia Carvajal-Vergara, Felipe Prosper, Xabier L. Aranguren
Publikováno v:
Stem Cell Research, Vol 21, Iss C, Pp 1-4 (2017)
We generated ATCi-MF1 induced pluripotent stem (iPS) cell line from Macaca fascicularis adult skin fibroblasts using non-integrative Sendai viruses carrying OCT3/4, KLF4, SOX2 and c-MYC. Once established, ATCi-MF1 cells present a normal karyotype, ar
Externí odkaz:
https://doaj.org/article/2ff40b6c1b0947f09bbc067b04f1c633