Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Xabier L Aranguren"'
Autor:
Ander Muniategui, Rubén Nogales-Cadenas, Miguél Vázquez, Xabier L Aranguren, Xabier Agirre, Aernout Luttun, Felipe Prosper, Alberto Pascual-Montano, Angel Rubio
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30766 (2012)
miRNAs are small RNA molecules (' 22nt) that interact with their corresponding target mRNAs inhibiting the translation of the mRNA into proteins and cleaving the target mRNA. This second effect diminishes the overall expression of the target mRNA. Se
Externí odkaz:
https://doaj.org/article/2caafa8f3d9849b2a130987011696966
Autor:
Marta Moya-Jódar, Asier Ullate-Agote, Paula Barlabé, Juan Roberto Rodríguez-Madoz, Gloria Abizanda, Carolina Barreda, Xonia Carvajal-Vergara, Amaia Vilas-Zornoza, Juan Pablo Romero, Leire Garate, Xabier Agirre, Giulia Coppiello, Felipe Prósper, Xabier L. Aranguren
Publikováno v:
Stem Cell Reports, Vol 18, Iss 1, Pp 64-80 (2023)
Summary: Naive human pluripotent stem cells (hPSCs) are defined as the in vitro counterpart of the human preimplantation embryo’s epiblast and are used as a model system to study developmental processes. In this study, we report the discovery and c
Externí odkaz:
https://doaj.org/article/5525088ab778485bae0f0d5d92dd1f1f
Autor:
Pilar Montero-Calle, María Flandes-Iparraguirre, Bernd Kuebler, Begoña Arán, Eduardo Larequi, Ilazki Anaut, Giulia Coppiello, Xabier L. Aranguren, Anna Veiga, Maria Teresa Basurte Elorz, Manuel García de Yébenes, Juan J. Gavira, Felipe Prósper, Olalla Iglesias-García, Manuel M. Mazo Vega
Publikováno v:
Stem Cell Research, Vol 71, Iss , Pp 103189- (2023)
Transthyretin (TTR) amyloid cardiomyopathy (ATTR-CM) is a life-threatening disease caused by the abnormal production of misfolded TTR protein by liver cells, which is then released systemically. Its amyloid deposition in the heart is linked to cardia
Externí odkaz:
https://doaj.org/article/d9e76d653cf74761bd4fed055fcc36eb
Autor:
Miriam Bobadilla Muñoz, Josune Orbe, Gloria Abizanda, Florencio J. D. Machado, Amaia Vilas, Asier Ullate-Agote, Leire Extramiana, Arantxa Baraibar Churio, Xabier L. Aranguren, Gloria Cantero, Neira Sáinz Amillo, José Antonio Rodríguez, Luis Ramos García, Juan Pablo Romero Riojas, Ainara Vallejo-Illarramendi, Carmen Paradas, Adolfo López de Munain, José Antonio Páramo, Felipe Prósper, Ana Pérez-Ruiz
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Aged muscles accumulate satellite cells with a striking decline response to damage. Although intrinsic defects in satellite cells themselves are the major contributors to aging-associated stem cell dysfunction, increasing evidence suggests that chang
Externí odkaz:
https://doaj.org/article/6f3b235d66ea48b0903667a7547e22f3
Autor:
Javier Linares, Leyre López-Muneta, Estibaliz Arellano-Viera, Purificación Ripalda-Cemboráin, Elena Iglesias, Gloria Abizanda, Xabier L. Aranguren, Felipe Prósper, Xonia Carvajal-Vergara
Publikováno v:
Stem Cell Research, Vol 33, Iss , Pp 125-129 (2018)
Islet-1 (Isl1) is a transcription factor essential for life expressed in specific cells with different developmental origins. We have generated iPSC lines from fibroblasts of the transgenic Ai6 x Isl1-Cre (Ai6IslCre) mouse. Here we describe the compl
Externí odkaz:
https://doaj.org/article/caba4b1a8fb64ca1b63c94bdd722c56a
Autor:
Giulia Coppiello, Gloria Abizanda, Natalia Aguado, Elena Iglesias, Olalla Iglesias-Garcia, Antonio Lo Nigro, Felipe Prosper, Xabier L. Aranguren
Publikováno v:
Stem Cell Research, Vol 21, Iss C, Pp 47-50 (2017)
We generated a rat iPSC line called ATCi-rSD95 from transgenic Sprague-Dawley GFP fetal fibroblasts. Established ATCi-rSD95 cells present a normal karyotype, silencing of the transgenes and express pluripotency-associated markers. Additionally, ATCi-
Externí odkaz:
https://doaj.org/article/73eed17e5cc04da1821105c9d04d7bef
Autor:
Giulia Coppiello, Gloria Abizanda, Natalia Aguado, Elena Iglesias, Olalla Iglesias-Garcia, Antonio Lo Nigro, Felipe Prosper, Xabier L. Aranguren
Publikováno v:
Stem Cell Research, Vol 21, Iss C, Pp 40-43 (2017)
We generated two rat embryonic stem cell (ESC) lines: ATCe-SD7.8 from Sprague-Dawley strain and ATCe-WK1 from Wistar Kyoto strain. Cells were marked with enhanced green fluorescent protein (eGFP) by transduction with a lentiviral vector. Cells presen
Externí odkaz:
https://doaj.org/article/540e324bbd254cb2b37c1984b9942973
Autor:
Giulia Coppiello, Gloria Abizanda, Natalia Aguado, Elena Iglesias, Estibaliz Arellano-Viera, Juan R Rodriguez-Madoz, Xonia Carvajal-Vergara, Felipe Prosper, Xabier L. Aranguren
Publikováno v:
Stem Cell Research, Vol 21, Iss C, Pp 1-4 (2017)
We generated ATCi-MF1 induced pluripotent stem (iPS) cell line from Macaca fascicularis adult skin fibroblasts using non-integrative Sendai viruses carrying OCT3/4, KLF4, SOX2 and c-MYC. Once established, ATCi-MF1 cells present a normal karyotype, ar
Externí odkaz:
https://doaj.org/article/2ff40b6c1b0947f09bbc067b04f1c633
Autor:
Giulia Coppiello, Paula Barlabé, Marta Moya-Jódar, Gloria Abizanda, Carolina Barreda, Elena Iglesias, Javier Linares, Estibaliz Arellano-Viera, Adrian Ruiz-Villalba, Eduardo Larequi, Xonia Carvajal-Vergara, Beatriz Pelacho, Felipe Prósper, Xabier L. Aranguren
SUMMARYThe generation of organs from stem cells by blastocyst complementation is a promising approach to cover the clinical need for transplants. In order to generate rejection-free organs, complementation of both parenchymal and vascular cells must
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e182a0c05dbc4506336b3bbb3c98970
https://doi.org/10.1101/2022.10.04.510637
https://doi.org/10.1101/2022.10.04.510637
Autor:
Marta Moya-Jódar, Asier Ullate-Agote, Paula Barlabé, Juan Roberto Rodríguez-Madoz, Gloria Abizanda, Carolina Barreda, Xonia Carvajal-Vergara, Amaia Vilas-Zornoza, Juan Pablo Romero, Leire Garate, Xabier Agirre, Giulia Coppiello, Felipe Prósper, Xabier L. Aranguren
Naïve human pluripotent stem cells (hPSCs) are defined as the in vitro counterpart of the human preimplantation embryo’s epiblast and are used as a model system to study developmental processes. In this study, we report the discovery and character
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9307cd309ad995b3cb2f14d089424a8
https://doi.org/10.1101/2022.03.06.482812
https://doi.org/10.1101/2022.03.06.482812