Zobrazeno 1 - 10
of 143
pro vyhledávání: '"XUELIAN ZHENG"'
Autor:
Tingting Fan, Yanhao Cheng, Yuechao Wu, Shishi Liu, Xu Tang, Yao He, Shanyue Liao, Xuelian Zheng, Tao Zhang, Yiping Qi, Yong Zhang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Cytosine base editors (CBEs) and adenine base editors (ABEs) enable precise C-to-T and A-to-G edits. Recently, ABE8e, derived from TadA-8e, enhances A-to-G edits in mammalian cells and plants. Interestingly, TadA-8e can also be evolved to co
Externí odkaz:
https://doaj.org/article/4d3f41c610934d3783cf74779779f267
Publikováno v:
IEEE Access, Vol 12, Pp 56344-56355 (2024)
Driving behavior primitives play a crucial role in semantic explanation of driving behaviors. Although much work has been done on exacting driving behavior primitives from naturalistic driving data, few studies was published on primitive classificati
Externí odkaz:
https://doaj.org/article/fe631be0f8ac40febbaabdc916c4e6c2
Autor:
Zhaohui Zhong, Guanqing Liu, Zhongjie Tang, Shuyue Xiang, Liang Yang, Lan Huang, Yao He, Tingting Fan, Shishi Liu, Xuelian Zheng, Tao Zhang, Yiping Qi, Jian Huang, Yong Zhang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Among CRISPR-Cas genome editing systems, Streptococcus pyogenes Cas9 (SpCas9), sourced from a human pathogen, is the most widely used. Here, through in silico data mining, we have established an efficient plant genome engineering system usin
Externí odkaz:
https://doaj.org/article/8e7682ada5eb4553a6a8e35edf883a37
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Objective: The present systematic review and meta-analysis aimed to estimate the prophylactic effect of alpha blockers against postoperative urinary retention (POUR) in orthopaedic patients.Methods: PubMed, Embase, Web of Science and Cochrane Library
Externí odkaz:
https://doaj.org/article/063ac0d65f39485eaa98c7794ca0444f
Autor:
Xuelian Zheng, Shuting Zhang, Yanling Liang, Rui Zhang, Li Liu, Pengchen Qin, Zhe Zhang, Yan Wang, Jianping Zhou, Xu Tang, Yong Zhang
Publikováno v:
The Plant Genome, Vol 16, Iss 2, Pp n/a-n/a (2023)
Abstract Cytokinin (CTK) is an important plant hormone that promotes cell division, controls cell differentiation, and regulates a variety of plant growth and development processes. Cytokinin oxidase/dehydrogenase (CKX) is an irreversible cytokinin
Externí odkaz:
https://doaj.org/article/75ec99a49cf844bb96fd0843bc1f1ee4
Autor:
Yingxiao Zhang, Qiurong Ren, Xu Tang, Shishi Liu, Aimee A. Malzahn, Jianping Zhou, Jiaheng Wang, Desuo Yin, Changtian Pan, Mingzhu Yuan, Lan Huang, Han Yang, Yuxin Zhao, Qing Fang, Xuelian Zheng, Li Tian, Yanhao Cheng, Ysa Le, Bailey McCoy, Lidiya Franklin, Jeremy D. Selengut, Stephen M. Mount, Qiudeng Que, Yong Zhang, Yiping Qi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
CRISPR-Cas12a is a promising system for targeting AT-rich regions of the genome. Here the authors identify Cas12a orthologs with expanded targeting scope and develop a highly multiplexable editing system in rice.
Externí odkaz:
https://doaj.org/article/d6eb08b3515f47118d396c6a80d7329c
Autor:
Zhaohui Zhong, Shishi Liu, Xiaopei Liu, Binglin Liu, Xu Tang, Qiurong Ren, Jianping Zhou, Xuelian Zheng, Yiping Qi, Yong Zhang
Publikováno v:
Rice, Vol 13, Iss 1, Pp 1-13 (2020)
Abstract Background Expression of either Cas9 or Cas12a and guide RNAs by a single Polymerase II (Pol II) promoter represents a compact CRISPR expression system and has many advantages for different applications. In order to make this system routine
Externí odkaz:
https://doaj.org/article/5574553124f84f059fffcaed890b1c02
Autor:
Qiong Wang, Peipei Wang, Li Zhang, Mathewos Tessema, Lang Bai, Xiuling Xu, Qin Li, Xuelian Zheng, Bryanna Saxton, Wenshu Chen, Randy Willink, Zhiping Li, Lin Zhang, Steven A. Belinsky, Xia Wang, Bin Zhou, Yong Lin
Publikováno v:
Translational Oncology, Vol 13, Iss 2, Pp 372-382 (2020)
INTRODUCTION: The efficacy of chemotherapeutic agents in killing cancer cells is mainly attributed to the induction of apoptosis. However, the tremendous efforts on enhancing apoptosis-related mechanisms have only moderately improved lung cancer chem
Externí odkaz:
https://doaj.org/article/31157af9944546cdba55b2425f61c6df
Autor:
Simon Sretenovic, Shishi Liu, Gen Li, Yanhao Cheng, Tingting Fan, Yang Xu, Jianping Zhou, Xuelian Zheng, Gary Coleman, Yong Zhang, Yiping Qi
Publikováno v:
Frontiers in Genome Editing, Vol 3 (2021)
As a precise genome editing technology, base editing is broadly used in both basic and applied plant research. Cytosine base editors (CBEs) and adenine base editors (ABEs) represent the two commonly used base editor types that mediate C-to-T and A-to
Externí odkaz:
https://doaj.org/article/58539973d462469c9535d1dc7bfd4b21
Autor:
Aimee A. Malzahn, Xu Tang, Keunsub Lee, Qiurong Ren, Simon Sretenovic, Yingxiao Zhang, Hongqiao Chen, Minjeong Kang, Yu Bao, Xuelian Zheng, Kejun Deng, Tao Zhang, Valeria Salcedo, Kan Wang, Yong Zhang, Yiping Qi
Publikováno v:
BMC Biology, Vol 17, Iss 1, Pp 1-14 (2019)
Abstract Background CRISPR-Cas12a (formerly Cpf1) is an RNA-guided endonuclease with distinct features that have expanded genome editing capabilities. Cas12a-mediated genome editing is temperature sensitive in plants, but a lack of a comprehensive un
Externí odkaz:
https://doaj.org/article/90a2e580ce324569b3ff72d77e2eb6cb