Zobrazeno 1 - 10
of 329
pro vyhledávání: '"XIAOFAN JIANG"'
Autor:
Zhuoyuan Zhang, Xiangyu Gao, Zhicheng Tian, Erwan Yang, Yutao Huang, Dan Liu, Shuhui Dai, Haofuzi Zhang, Mingdong Bao, Xiaofan Jiang, Xin Li, Peng Luo
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-16 (2024)
Abstract Glutamate receptor (GluR)-mediated excitotoxicity is an important mechanism causing delayed neuronal injury after traumatic brain injury (TBI). Preso, as a core scaffolding protein of postsynaptic density (PSD), is considered an important re
Externí odkaz:
https://doaj.org/article/e98f19a1a574413290b397b29dd44419
Autor:
Shiwen Huo, Jinqi Xue, Shuo Wang, Huilian Shan, Guanglei Chen, Nan Niu, Yimin Wang, Fang Qiu, Yi Zhao, Fei Xing, Xinyu Zheng, Wei Tu, Ke Li, Hai Zhao, Meiyue Tang, Qianshi Xu, Chao Liu, Yafei Zhao, Xiaofan Jiang, Zheng Pang, Keliang Zhang, Dianlong Zhang, Zhe‐Sheng Chen, Caigang Liu
Publikováno v:
MedComm, Vol 5, Iss 3, Pp n/a-n/a (2024)
Abstract Triple‐positive breast cancer (TPBC) poorly responds to current standard neoadjuvant therapy (trastuzumab plus pertuzumab and chemotherapy). Our previous MUKDEN 01 study showed a promising total pathological complete response (tpCR) rate o
Externí odkaz:
https://doaj.org/article/90fd47107198425c8ce96e8bc7172b7d
Autor:
Yueying Liu, Yuanjin Chang, Xiaofan Jiang, Huiya Mei, Yingsi Cao, Dongqin Wu, Ruijin Xie, Wenjun Jiang, Emely Vasquez, Yu Wu, Shunyan Lin, Yachuan Cao
Publikováno v:
Heliyon, Vol 10, Iss 4, Pp e26219- (2024)
Background: Epilepsy is recognized as the most common chronic neurological condition among children, and hippocampal neuronal cell death has been identified as a crucial factor in the pathophysiological processes underlying seizures. In recent studie
Externí odkaz:
https://doaj.org/article/e3344738bdfa401faab9484c9a601bc1
Autor:
Haofuzi Zhang, Jidong Sun, Peng Zou, Yutao Huang, Qiuzi Yang, Zhuoyuan Zhang, Peng Luo, Xiaofan Jiang
Publikováno v:
Heliyon, Vol 10, Iss 4, Pp e25866- (2024)
Background: The immune microenvironment and hypoxia play crucial roles in the pathophysiology of ischemic stroke (IS). Hence, in this study, we aimed to identify hypoxia- and immune-related biomarkers in IS. Methods: The IS microarray dataset GSE1656
Externí odkaz:
https://doaj.org/article/487bede3f69d4b3eabe107e144c91220
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2024)
Platelets play critical roles in maintaining hemostasis. The blood brain barrier (BBB), a significant physical and metabolic barrier, helps maintain physiological stability by limiting transportations between the blood and neural tissues. When the br
Externí odkaz:
https://doaj.org/article/2a108ad030ba49709b54e02aaa205a61
Autor:
Xiaowei Fei, Ya-nan Dou, Kai Sun, Jialiang Wei, Qingdong Guo, Li Wang, Xiuquan Wu, Weihao Lv, Xiaofan Jiang, Zhou Fei
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 6, Pp 1203-1217 (2023)
Abstract The tripartite motif (TRIM) 22 and mitogen-activated protein kinase (MAPK) signaling pathways play critical roles in the growth of glioblastoma (GBM). However, the molecular mechanism underlying the relationship between TRIM22 and MAPK signa
Externí odkaz:
https://doaj.org/article/fd8d595eb7ab4823a40628e3c69a212f
Autor:
Guanglei Chen, Xi Gu, Jinqi Xue, Xu Zhang, Xiaopeng Yu, Yu Zhang, Ailin Li, Yi Zhao, Guijin He, Meiyue Tang, Fei Xing, Jianqiao Yin, Xiaobo Bian, Ye Han, Shuo Cao, Chao Liu, Xiaofan Jiang, Keliang Zhang, Yan Xia, Huajun Li, Nan Niu, Caigang Liu, On behalf of the Northeastern Clinical Research Alliance of Oncology (NCRAO)
Publikováno v:
eLife, Vol 12 (2023)
Background: Emerging data have supported the immunostimulatory role of radiotherapy, which could exert a synergistic effect with immune checkpoint inhibitors (ICIs). With proven effective but suboptimal effect of ICI and chemotherapy in triple-negati
Externí odkaz:
https://doaj.org/article/4d40ffdb0c304d388f1adabf0f97596c
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
BackgroundThe study introduced the Pediatric Quality of Life Inventory™ (PedsQL™) brain tumor module for the first time in China. Further, the Chinese version of the PedsQL™ brain tumor module was developed and its feasibility, reliability, and
Externí odkaz:
https://doaj.org/article/28645864018d4f45bda7742baf0f05c7
Autor:
Zhicheng Tian, Zixuan Cao, Erwan Yang, Juan Li, Dan Liao, Fei Wang, Taozhi Wang, Zhuoyuan Zhang, Haofuzi Zhang, Xiaofan Jiang, Xin Li, Peng Luo
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 12, Pp 2711-2719 (2023)
[INLINE:1] The cumulative damage caused by repetitive mild traumatic brain injury can cause long-term neurodegeneration leading to cognitive impairment. This cognitive impairment is thought to result specifically from damage to the hippocampus. In th
Externí odkaz:
https://doaj.org/article/6a0aa110d2c94c3ea495f7c9081938fa
Publikováno v:
Biomolecules, Vol 14, Iss 3, p 378 (2024)
Ischemic stroke is a fatal and disabling disease worldwide and imposes a significant burden on society. At present, biological markers that can be conveniently measured in body fluids are lacking for the diagnosis of ischemic stroke, and there are no
Externí odkaz:
https://doaj.org/article/5e56196f205740f18a077d34a220fb95