Zobrazeno 1 - 10
of 166
pro vyhledávání: '"XAV939"'
Publikováno v:
Egyptian Liver Journal, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Background Two chief hurdles in most cancer treatments are chemoresistance and tumor recurrence, especially counting hepatocellular carcinoma (HCC). Most conformist chemotherapy fails to completely cure HCC patients because of its susceptibi
Externí odkaz:
https://doaj.org/article/107b48838b80435c982424f619b3375a
Wnt signaling blockade is essential for maintaining the pluripotency of chicken embryonic stem cells
Autor:
Ryota Kajihara, Ryo Ezaki, Kennosuke Ichikawa, Tenkai Watanabe, Takumi Terada, Mei Matsuzaki, Hiroyuki Horiuchi
Publikováno v:
Poultry Science, Vol 103, Iss 2, Pp 103361- (2024)
ABSTRACT: Activation of Wnt/β-catenin signaling supports the self-renewal of mouse embryonic stem cells. We aimed to understand the effects of Wnt signaling activation or inhibition on chicken embryonic stem cells (chESCs), as these effects are larg
Externí odkaz:
https://doaj.org/article/389f611ad7c749fc8b74dccae9b61636
Autor:
Chetan Pundkar, Ferrin Antony, Xuejia Kang, Amarjit Mishra, R. Jayachandra Babu, Pengyu Chen, Feng Li, Amol Suryawanshi
Publikováno v:
Heliyon, Vol 9, Iss 6, Pp e16688- (2023)
The aberrant activation of Wnt/β-catenin signaling in tumor cells and immune cells in the tumor microenvironment (TME) promotes malignant transformation, metastasis, immune evasion, and resistance to cancer treatments. The increased Wnt ligand expre
Externí odkaz:
https://doaj.org/article/d0e476ae385048e2814172ef12023c24
Autor:
Yoshifumi Hotta, Keiichiro Nishida, Aki Yoshida, Yoshihisa Nasu, Ryuichi Nakahara, Shuichi Naniwa, Noriyuki Shimizu, Chinatsu Ichikawa, Deting Lin, Tomohiro Fujiwara, Toshifumi Ozaki
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1443 (2024)
We investigated the effects of a Tankyrase (TNKS-1/2) inhibitor on mechanical stress-induced gene expression in human chondrocytes and examined TNKS-1/2 expression in human osteoarthritis (OA) cartilage. Cells were seeded onto stretch chambers and in
Externí odkaz:
https://doaj.org/article/4f73d21a8c14442cb4441b65de6389bf
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/ebeeb0e4d7ad4da8ba0bc7889315449e
Publikováno v:
ASM Science Journal, Vol 15, Pp 1-6 (2021)
Syzygium polycephaloides, a plant native to Southeast Asia, is used to cure common illnesses. In this study, the methanolic bark extracts of S. polycephaloides was evaluated for their antibacterial activity and screened for their Wnt signal inhibitor
Externí odkaz:
https://doaj.org/article/f941e9b6303a453faab6929920484690
Autor:
Jinhua Zhang, Jing Si, Lu Gan, Menghuan Guo, Junfang Yan, Yuhong Chen, Fang Wang, Yi Xie, Yupei Wang, Hong Zhang
Publikováno v:
Artificial Cells, Nanomedicine, and Biotechnology, Vol 48, Iss 1, Pp 479-487 (2020)
Cervical cancer is the second most common malignant tumour threatening women’s health. In recent years, heavy-ion beam therapy is becoming a newly emerging therapeutic mean of cancer; however, radio-resistance and radiation-induced damage constitut
Externí odkaz:
https://doaj.org/article/a033a869bbf3441e8d28f70e63772856
Akademický článek
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Akademický článek
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Autor:
Yueyang Zhong, Kai Wang, Yin Zhang, Qichuan Yin, Su Li, Jiaming Wang, Xiaobo Zhang, Haijie Han, Ke Yao
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Corneal wound involves a series of complex and coordinated physiological processes, leading to persistent epithelial defects and opacification. An obstacle in the treatment of ocular diseases is poor drug delivery and maintenance. In this study, we c
Externí odkaz:
https://doaj.org/article/4fe46abec4eb44ccae46432d29e00043