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Hepatitis C virus reinfection following treatment among people who use drugs

Autor: Bart P. X. Grady, Janke Schinkel, X.V. Thomas, Olav Dalgard

Publikováno v: Clinical infectious diseases, 57(Suppl. 2), S105-S110. Oxford University Press

Most new cases of hepatitis C virus (HCV) infections in the developed world are associated with injection drug use. However, treatment for people who inject drugs (PWID) is controversial, as successful treatment risks being followed by new infection.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec582f46173fce01ff7487daf20408db
https://doi.org/10.1093/cid/cit301

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A molecular epidemiological perspective of rhinovirus types circulating in Amsterdam from 2007 to 2012

Autor: René Minnaar, Dasja Pajkrt, X.V. Thomas, Sjoerd Rebers, Katja C. Wolthers, Janke Schinkel, M.D. de Jong, L.M. van der Linden, Andrea H. L. Bruning

Publikováno v: Clinical Microbiology and Infection
Clinical microbiology and infection, 22(12), 1002.e9-1002.e14. Elsevier Limited

Rhinoviruses (RVs) are frequently detected respiratory viruses that cause mild common cold symptoms, but may also lead to more severe respiratory tract infections. The large number of RV types, classified into species A, B and C, hampers clear insigh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b34811f1f40a5c9bb4d2a7ae06122468
https://pubmed.ncbi.nlm.nih.gov/27554204

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Clinical, virological and epidemiological characteristics of rhinovirus infections in early childhood: A comparison between non-hospitalised and hospitalised children

Autor: Peter J. Sterk, Joanne G. Wildenbeest, Rogier R. Jansen, Dasja Pajkrt, X.V. Thomas, Marc P. van der Schee, Lonneke van der Linden, Katja C. Wolthers, René Minnaar, Menno D. de Jong, Andrea H. L. Bruning

Publikováno v: Journal of clinical virology, 73, 120-126. Elsevier
Journal of Clinical Virology

Highlights • Rhinoviruses (RV) frequently cause respiratory tract infections in young children. • We evaluated characteristics of RV infections in relation to clinical outcome. • In young children clinical outcome was not related to RV species

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::088fbeef464515f75a5219fa2c46f707
https://pure.amc.nl/en/publications/clinical-virological-and-epidemiological-characteristics-of-rhinovirus-infections-in-early-childhood-a-comparison-between-nonhospitalised-and-hospitalised-children(18007dfb-e5ca-4f26-b030-ac5846228c1b).html

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Genetic characterization of multiple hepatitis C virus infections following acute infection in HIV-infected men who have sex with men

Autor: Sjoerd Rebers, Janke Schinkel, Menno D. de Jong, Richard Molenkamp, Maria Prins, Bart P. X. Grady, Joost W. Vanhommerig, Cynthia K. Y. Ho, Marc van der Valk, Jan van der Meer, X.V. Thomas

Publikováno v: AIDS (London, England), 29(17), 2287-2295. Lippincott Williams and Wilkins

OBJECTIVE High rates of hepatitis C virus (HCV) reinfections among HIV-infected men who have sex with men (MSM) following clearance of a primary infection suggest absence of protective immunity. Here, we investigated the incidence of HCV super and re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::853ea12893345635020cedbcbb508519
https://pure.amc.nl/en/publications/genetic-characterization-of-multiple-hepatitis-c-virus-infections-following-acute-infection-in-hivinfected-men-who-have-sex-with-men(0f0360b8-be5f-47e5-b9a6-2e0d20fa208f).html

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Evolutionary dynamics of hepatitis C virus NS3 protease domain during and following treatment with narlaprevir, a potent NS3 protease inhibitor

Autor: X.V. Thomas, M. A. Treitel, R.J. de Knegt, Richard Molenkamp, Christine J. Weegink, Janke Schinkel, H. W. Reesink, J. de Bruijne, E. Hughes, J.F. Bergmann, H.L.A. Janssen, Sjoerd Rebers

Publikováno v: Journal of viral hepatitis, 20(11), 779-789. Wiley-Blackwell
Journal of Viral Hepatitis, 20(11), 779-789. Wiley-Blackwell Publishing Ltd

Narlaprevir, a hepatitis C virus (HCV) NS3/4A serine protease inhibitor, has demonstrated robust antiviral activity in a placebo-controlled phase 1 study. To study evolutionary dynamics of resistant variants, the NS3 protease sequence was clonally an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3cfa41a51fc55f74b257a692b52180b
https://pure.amc.nl/en/publications/evolutionary-dynamics-of-hepatitis-c-virus-ns3-protease-domain-during-and-following-treatment-with-narlaprevir-a-potent-ns3-protease-inhibitor(4896dcbd-c176-44f6-ad52-db1230549611).html

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Colonial history and contemporary transmission shape the genetic diversity of hepatitis C virus genotype 2 in Amsterdam

Autor: G.E.L. van den Berk, Janke Schinkel, MH Prins, X.V. Thomas, T. van Laar, Christine J. Weegink, Peter V. Markov, Oliver G. Pybus, Sem J. Aronson

Publikováno v: Markov, P V, van de Laar, T J W, Thomas, X V, Aronson, S J, Weegink, C J, van den Berk, G E, Prins, M, Pybus, O G & Schinkel, J 2012, ' Colonial History and Contemporary Transmission Shape the Genetic Diversity of Hepatitis C Virus Genotype 2 in Amsterdam ', Journal of Virology, vol. 86, no. 14, pp. 7677-7687 . https://doi.org/10.1128/JVI.06910-11
Journal of Virology, 86(14), 7677-7687. American Society for Microbiology
Journal of virology, 86(14), 7677-7687. American Society for Microbiology

Evolutionary analysis of hepatitis C virus (HCV) genome sequences has provided insights into the epidemic history and transmission of this widespread human pathogen. Here we report an exceptionally diverse set of 178 HCV genotype 2 (HCV-2) isolates f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::442e2322abd7433bd5c37ec5f78d59f9
https://pubmed.ncbi.nlm.nih.gov/22573865

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