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Postoperative serum Vascular Endothelial Growth Factor is an independent prognostic factor of disease free survival and overall survival in patients with non metastatic colon cancer

Autor: Sandra Alonso, Sergi Mojal, X. Mayol, Miguel Pera, Marta Pascual, Luis Grande, Silvia Salvans, María José Gil

Publikováno v: The American Journal of Surgery. 216:255-259

Background Angiogenesis is essential for tumor growth and formation of metastasis. VEGF is the most potent agiogenic citokine. The aim was to investigate the predictive value of postoperative VEGF serum concentration in patients undergoing surgery fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7805a2a99a0032b033f6e232309e1d98
https://doi.org/10.1016/j.amjsurg.2017.06.037

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Akademický článek

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Peripheral blood leucocytes show differential expression of tumour progression-related genes in colorectal cancer patients who have a postoperative intra-abdominal infection: a prospective matched cohort study

Autor: S, Alonso, X, Mayol, L, Nonell, S, Salvans, M, Pascual, M, Pera, E, Puigdecanet

Publikováno v: Colorectal Disease. 19:O115-O125

Aim Anastomotic leak is associated with higher rates of recurrence after surgery for colorectal cancer. However, the mechanisms responsible are unknown. We hypothesized that the infection-induced inflammatory response may induce overexpression of tum

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ee4ca8ec5c4ecef7f90c8a3abe03edc
https://doi.org/10.1111/codi.13635

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Postoperative intra-abdominal infection is an independent prognostic factor of disease-free survival and disease-specific survival in patients with stage II colon cancer

Autor: P Sánchez-Velázquez, M Jiménez-Toscano, X Mayol, L Lorente, X Rogés, M. Gallen, Mar Iglesias, Miguel Pera

Recurrence occurs in up to 20% of patients with stage II colon cancer operated on for cure. Although postoperative intra-abdominal infection has been linked with an increased risk of recurrence, the association is controversial. The aim was to invest

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b403a258da6d63dcd452d603e96b1713
https://www.zora.uzh.ch/id/eprint/167901/

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Postoperative intra-abdominal infection and colorectal cancer recurrence: A prospective matched cohort study of inflammatory and angiogenic responses as mechanisms involved in this association

Autor: Miguel Pera, X. Mayol, Silvia Salvans, Sergi Mojal, Sandra Alonso, María José Gil, Marta Pascual, Luis Grande

Publikováno v: European Journal of Surgical Oncology (EJSO). 41:208-214

Background Anastomotic leakage is associated with higher rates of recurrence after surgery for colorectal cancer. However, the mechanisms responsible are unknown. The aim was to investigate the inflammatory and angiogenic responses in patients underg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1c7a1992a027b425e4bf17915bd9405
https://doi.org/10.1016/j.ejso.2014.10.052

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Distribution of fibronectin and fibronectin-binding proteins, AGp110 and integrin alpha 5 beta 1, during chemically induced hepatocarcinogenesis in adult rats

Autor: X. Mayol, R.C. Hughes, J.A. Green, S.C. Stamatoglou, M.M. Manson

Publikováno v: Journal of Cell Science. 100:599-604

We have used single- and double-label immunocytochemistry to examine the distribution of AGp110, integrin alpha 5 beta 1 and fibronectin in adult rat liver during carcinogenesis induced by aflatoxin B1 or diethylnitrosamine. In normal liver fibronect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d1dd284d2753fbcb7b1a070158452e9
https://doi.org/10.1242/jcs.100.3.599

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pRB, p107 and p130 as transcriptional regulators: role in cell growth and differentiation

Autor: X, Mayol, X, Graña

Publikováno v: Progress in cell cycle research. 3

The mammalian cell cycle engine, which is composed of cyclin/CDK holoenzymes, controls the progression throughout the cell cycle by regulating, at least in part, the transcription of two types of genes: genes whose protein products are required for D

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5f059c4e8146678968c410ebd0a3b83e
https://pubmed.ncbi.nlm.nih.gov/9580269

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G1 cyclin/CDK-independent phosphorylation and accumulation of p130 during the transition from G1 to G0 lead to its association with E2F-4

Autor: X, Mayol, J, Garriga, X, Graña

Publikováno v: Oncogene. 13(2)

During the transition from G1 to G0, p130 undergoes a specific phosphorylation event-leading to p130-form 2- that is mediated by a kinase/s other than the known G1, S and G2/M cyclin/CDKs. Changes in the phosphorylation status of p130 during this tra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::57a81b69089ee4c2b61fd68c8126696e
https://pubmed.ncbi.nlm.nih.gov/8710362

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