Zobrazeno 1 - 3
of 3
pro vyhledávání: '"X. M. De Luca"'
Autor:
Heather Thorne, A-M Patch, John F. Pearson, F Newell, Georgia Chenevix-Trench, Sriganesh Srihari, Vanessa Lakis, Katia Nones, Conrad Leonard, Sunil R. Lakhani, J Beasley, Peter T. Simpson, Michael T. Parsons, Mark A. Ragan, Aimee L Davidson, Amanda B. Spurdle, Andrea Degasperi, K. K. Khanna, Oliver Holmes, Julie K. Johnson, Kaltin Ferguson, Stephen H. Kazakoff, Serena Nik-Zainal, Scott Wood, Nick Waddell, Pamela Mukhopadhyay, Qinying Xu, X. M. De Luca, A.E. McCart Reed, Lynne Reid
Publikováno v:
Cancer Research. 79:P5-10
Approximately 10-15% of breast cancers are associated with a strong family history of disease. Pathogenic variants in BRCA1, BRCA2 or other moderate to highly penetrant susceptibility genes (e.g. TP53, ATM, CHEK2, PALB2 and PTEN) account for a number
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::317682359e8da6428f3291f702dbfddd
https://doi.org/10.1158/1538-7445.sabcs18-p5-10-01
https://doi.org/10.1158/1538-7445.sabcs18-p5-10-01
Autor:
Fares Al-Ejeh, Ana Cristina Vargas, A. Hasson, Mariska Miranda, P. Kalita-de Croft, Peter T. Simpson, X. M. De Luca, Jamie R. Kutasovic, K. K. Khanna, Jonathan Beesley, Jodi M. Saunus, Emad A. Rakha, Ashwini Raghavendra, Georgia Chenevix-Trench, Julia Margaret Wendy Gee, Samir Lal, Emarene Kalaw, Irma Gresshoff, Korinne Northwood, Christopher J. Ormandy, Ian O. Ellis, Malcolm Lim, Andrew J. Dalley, A.E. McCart Reed, Andrew R. Green, Sunil R. Lakhani, Dan V. Nicolau
BackgroundIntratumoural heterogeneity is a poor prognostic feature in triple-negative breast cancer (TNBC) and other high-grade malignancies. It is caused by genomic instability and phenotypic plasticity, but how these features co-evolve during tumou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f92ff5d4512d02716e3d46a042bfc3e
https://doi.org/10.1101/2021.03.30.437624
https://doi.org/10.1101/2021.03.30.437624
Autor:
Stephen H. Kazakoff, Julie Johnson, Nicola Waddell, Oliver Holmes, Sunil R. Lakhani, K. K. Khanna, Conrad Leonard, Michael T. Parsons, Peter T. Simpson, Vanessa Lakis, Katia Nones, Serena Nik-Zainal, Aimee L Davidson, Scott Wood, Andrea Degasperi, Georgia Chenevix-Trench, A.E. McCart Reed, Lynne Reid, John V. Pearson, Ann-Marie Patch, Kaltin Ferguson, X. M. De Luca, Sriganesh Srihari, Jonathan M. Harris, Jonathan Beesley, Mark A. Ragan, David G. Barnes, Heather Thorne, Pamela Mukhopadhyay, Felicity Newell, Qinying Xu, Amanda B. Spurdle
Publikováno v:
Ann Oncol
Background Whole-genome sequencing (WGS) is a powerful method for revealing the diversity and complexity of the somatic mutation burden of tumours. Here, we investigated the utility of tumour and matched germline WGS for understanding aetiology and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a412216dcef79f04224ef9da58a55a6a
https://pubmed.ncbi.nlm.nih.gov/31090898
https://pubmed.ncbi.nlm.nih.gov/31090898