Zobrazeno 1 - 10
of 11
pro vyhledávání: '"X. Grace Chiou"'
Autor:
Paul E. Wiedeman, Jay R. Luly, Julie Wilkins, Yung-Wu Chen, Gerard D. Gagne, Michael P. Sheets, Morey L. Smith, Usha Warrior, James M. Trevillyan, Stephen J. Ballaron, Jane A. Fagerland, X. Grace Chiou, Karl W. Mollison, George W. Carter, Earl J. Gubbins, Stevan W. Djuric
Publikováno v:
Journal of Biological Chemistry. 276:48118-48126
NFAT (nuclear factor of activated T cell) proteins are expressed in most immune system cells and regulate the transcription of cytokine genes critical for the immune response. The activity of NFAT proteins is tightly regulated by the Ca(2+)/calmoduli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::351374c705555e71a354368792ddee7c
https://doi.org/10.1074/jbc.m107919200
https://doi.org/10.1074/jbc.m107919200
Identification of Essential Residues for the Catalytic Function of 85-kDa Cytosolic Phospholipase A2
Autor:
Ruth M. Kramer, John D. Sharp, Laure J. Reynolds, Richard Todd Pickard, Ying K. Yee, Edward A. Dennis, Ann Louise Tebbe, X. Grace Chiou, Paul A. Hyslop, Beth A. Strifler, Michael Rosario Defelippis
Publikováno v:
Journal of Biological Chemistry. 271:19225-19231
Cytosolic phospholipase A2 (cPLA2) hydrolyzes the sn-2-acyl ester bond of phospholipids and shows a preference for arachidonic acid-containing substrates. We found previously that Ser-228 is essential for enzyme activity and is likely to function as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c11572130d706247e38787915684041
https://doi.org/10.1074/jbc.271.32.19225
https://doi.org/10.1074/jbc.271.32.19225
Autor:
Paul E. Kroeger, Kerri McWeeny, Stevan W. Djuric, X. Grace Chiou, Donald N. Halbert, James M. Trevillyan, Karl W. Mollison, Deanna L. Haasch, Regina M. Reilly, Yung-Wu Chen, Morey L. Smith, Sandra Koterski
Publikováno v:
Cellular immunology. 217(1-2)
In a search for novel early T cell activation transcripts, we identified expressed sequence tags (ESTs) more abundantly expressed in normal human CD4+ T lymphocytes fully activated by a 5 h exposure to CD3 plus CD28 mAbs, compared to the same cells s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9016c0d9374a98dcb81714917f3b4bed
https://pubmed.ncbi.nlm.nih.gov/12426003
https://pubmed.ncbi.nlm.nih.gov/12426003
Autor:
Richard J. Sciotti, Michael P. Sheets, X. Grace Chiou, Janet M. Parry, Beutel Bruce A, Bruce W. Surber, Stevan W. Djuric, Usha Warrior, Robert L. Simmer, James M. Trevillyan, David J. Burns, Karl W. Mollison
Publikováno v:
Journal of biomolecular screening. 4(3)
p38 is a member of the mitogen-activated protein kinase (MAPK) family of serine/threonine kinases, which is activated by cellular stressors and has been shown to be a critical enzyme in the synthesis and action of proinflammatory cytokines, tumor nec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::408c2d874cfb16d826e0f644b52c0479
https://pubmed.ncbi.nlm.nih.gov/10838421
https://pubmed.ncbi.nlm.nih.gov/10838421
Autor:
John D. Sharp, Christian C. Felder, Linda S. Ross, W. Scott Young, Daniel L. Sprague, Laura L. Lautens, X. Grace Chiou
Publikováno v:
Brain research. 809(1)
Cytosolic phospholipase A2 (cPLA2) catalyzes the selective release of arachidonic acid from the sn-2 position of membrane phospholipids and has been suggested as an effector in the receptor-mediated release of arachidonic acid in signal transduction.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48ebab71cb32d2d00fdd9c4ae2a322c2
https://pubmed.ncbi.nlm.nih.gov/9795110
https://pubmed.ncbi.nlm.nih.gov/9795110
Autor:
John D. Sharp, Ruth M. Kramer, Laura Cox, X. Grace Chiou, Bruce D. Gitter, Joseph Manetta, James A. Clemens, Donald L. White, Diane T. Stephenson, Patrick C. May
Publikováno v:
Brain research. 637(1-2)
Calcium-sensitive cytosolic phospholipase A 2 (cPLA 2 ) is responsible for receptor-mediated liberation of arachidonic acid, and thus plays an important role in the initiation of the inflammatory lipid-mediator cascade generating eicosanoids and plat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f3875d449c5182761e4ae3b163e9a22
https://pubmed.ncbi.nlm.nih.gov/8180824
https://pubmed.ncbi.nlm.nih.gov/8180824
Autor:
Ralph M. Riggin, Jennifer S. Small, Mcclure Don B, Andrew I. Louis, Steven Kovacevic, Tamara K. Wyrick, John D. Sharp, James R. Miller, Daniel Stark, X. Grace Chiou, Edda F. Roberts, Robert M. Ellis, Ruth M. Kramer, Gerald W. Becker, JoAnn Hoskins
Publikováno v:
Bio/technology (Nature Publishing Company). 12(1)
The 85-kD cytosolic phospholipase A2 (cPLA2) is a novel receptor-regulated phospholipase that is thought to initiate the production of inflammatory lipid mediators. Since cPLA2 is present only in minute amounts (less than 0.01% of total cellular prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdbec2f410f13407fd0a46961513efd3
https://pubmed.ncbi.nlm.nih.gov/7764328
https://pubmed.ncbi.nlm.nih.gov/7764328
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