Zobrazeno 1 - 10
of 63
pro vyhledávání: '"X. Charlie Dong"'
Autor:
Matthew Martin, Aishat Motolani, Hyeong-Geug Kim, Amy M. Collins, Faranak Alipourgivi, Jiamin Jin, Han Wei, Barry A. Wood, Yao-Ying Ma, X. Charlie Dong, Raghavendra G. Mirmira, Tao Lu
Publikováno v:
Biomolecules, Vol 13, Iss 10, p 1457 (2023)
Dysregulation of metabolic functions in the liver impacts the development of diabetes and metabolic disorders. Normal liver function can be compromised by increased inflammation via the activation of signaling such as nuclear factor (NF)-κB signalin
Externí odkaz:
https://doaj.org/article/fe15b2cdd26a480d8b9e5d43cb4c7d13
Autor:
Zhipeng Tao, Limin Shi, Jane Parke, Louise Zheng, Wei Gu, X. Charlie Dong, Dongmin Liu, Zongwei Wang, Aria F. Olumi, Zhiyong Cheng
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/7e7df97caa704a9e81c0107c0cc70733
Autor:
Zhipeng Tao, Limin Shi, Jane Parke, Louise Zheng, Wei Gu, X. Charlie Dong, Dongmin Liu, Zongwei Wang, Aria F. Olumi, Zhiyong Cheng
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-10 (2021)
Abstract Sex difference in adiposity has long been recognized but the mechanism remains incompletely understood. Previous studies suggested that adiposity was regulated by autophagy in response to energy status change. Here, we show that the energy s
Externí odkaz:
https://doaj.org/article/60f0180f84f447caaefe7e470f9749e0
Autor:
X. Charlie Dong
Publikováno v:
Cells, Vol 12, Iss 4, p 663 (2023)
Sirtuin 6 (SIRT6) is an NAD-dependent deacetylase/deacylase/mono-ADP ribosyltransferase, a member of the sirtuin protein family. SIRT6 has been implicated in hepatic lipid homeostasis and liver health. Hepatic lipogenesis is driven by several master
Externí odkaz:
https://doaj.org/article/c42ff0a4a1274218b2623bf027858c8f
Autor:
Zhigang Fang, Hyeong-Geug Kim, Menghao Huang, Kushan Chowdhury, Ming O. Li, Suthat Liangpunsakul, X. Charlie Dong
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 3, Pp 921-942 (2021)
Background & Aims: Sestrin 1/2/3 (Sesn1/2/3) belong to a small family of proteins that have been implicated in the regulation of metabolic homeostasis and oxidative stress. However, the underlying mechanisms remain incompletely understood. The aim of
Externí odkaz:
https://doaj.org/article/3588e0dfe11d4eb5b63675600dfb6ab9
Autor:
Xiaolin Zhong, Menghao Huang, Hyeong-Geug Kim, Yang Zhang, Kushan Chowdhury, Wenjie Cai, Romil Saxena, Robert F. Schwabe, Suthat Liangpunsakul, X. Charlie Dong
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 2, Pp 341-364 (2020)
Background & Aims: Nonalcoholic steatohepatitis (NASH) is a chronic liver disease that is manifested clinically by an increase in hepatic triglycerides, inflammation, and fibrosis. The pathogenesis of NASH remains incompletely understood. Sirtuin 6 (
Externí odkaz:
https://doaj.org/article/c06b524905434e42ad26ee0957994494
Autor:
X. Charlie Dong
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 11, Pp 1361-1362 (2020)
Externí odkaz:
https://doaj.org/article/788081ec26744c8baf38fae918b12e78
Autor:
X. Charlie Dong
Publikováno v:
Liver Research, Vol 1, Iss 3, Pp 168-173 (2017)
Non-alcoholic fatty liver disease (NAFLD) is a chronic progressive liver disorder that begins with simple hepatic steatosis and progresses to non-alcoholic steatohepatitis, fibrosis, cirrhosis, and even liver cancer. As the global prevalence of NAFLD
Externí odkaz:
https://doaj.org/article/495cb15111724427a22f8f9a98bec30a
Autor:
Suthat Liangpunsakul, Evelyn Toh, Ruth A. Ross, Laura E. Heathers, Kristina Chandler, AdePeju Oshodi, Breann McGee, Elizabeth Modlik, Tobyn Linton, Darrin Mangiacarne, Claudie Jimenez, X. Charlie Dong, Li Wang, Wanzhu Tu, David E. Nelson
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-7 (2017)
Abstract It is unknown if LPS (lipopolysaccharides) and markers of immune activation, soluble CD14 (sCD14) and CD163 (sCD163) are associated with the quantity of alcohol consumption. 148 subjects were enrolled (97 excessive drinkers (ED) and 51 contr
Externí odkaz:
https://doaj.org/article/43223bad8bfa489eae116c4d4e66b2c2
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 10, Pp 2745-2753 (2013)
Cholesterol homeostasis is crucial for cellular function and organismal health. The key regulator for the cholesterol biosynthesis is sterol-regulatory element binding protein (SREBP)-2. The biochemical process and physiological function of SREBP-2 h
Externí odkaz:
https://doaj.org/article/bf53d7a77fde4148b87283476cac0cd8