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Akademický článek

UNDERSTANDING USER EQUILIBRIUM STATES OF ROAD NETWORKS USING BIG TRAJECTORY DATA

Autor: B. Y. Chen, X.-Y. Chen, H.-P. Chen

Publikováno v: The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, Vol XLVIII-1-W2-2023, Pp 331-337 (2023)

User equilibrium (UE) has long been regarded as the cornerstone of transport planning studies. Despite its fundamental importance, our understanding of the actual UE state of road networks has remained surprisingly incomplete. Using big datasets of t

Externí odkaz: https://doaj.org/article/d8ebe4d226fe427f81af2d95c01db552

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Akademický článek

A2AR eGFP reporter mouse enables elucidation of A2AR expression dynamics during anti-tumor immune responses

Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)

Abstract There is significant clinical interest in targeting adenosine-mediated immunosuppression, with several small molecule inhibitors having been developed for targeting the A2AR receptor. Understanding of the mechanism by which A2AR is regulated

Externí odkaz: https://doaj.org/article/b9c76314c12142099494e8759d06a025

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Akademický článek

Challenges Of ACI 318-19 Revisions To Flexural Design Of RC Beams Considering Higher-strength Reinforcements

Autor: J. D. Yau, Y. C. Lee, X. Y. Chen

Publikováno v: Journal of Applied Science and Engineering, Vol 26, Iss 1, Pp 131-140 (2022)

For flexural design, the 2019 Building Code of the American Concrete Institute (ACI 318-19) revisions allows the use of high-strength reinforcements and concretes as well as new reinforcement strain limits for reinforced concrete (RC) structures. As

Externí odkaz: https://doaj.org/article/e9920b3175d74de5b29e19961560c336

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Akademický článek

MAIT cells regulate NK cell-mediated tumor immunity

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)

Mucosal-associated invariant T (MAIT) cells facilitate anti-microbial responses, but their functions in cancer protection is unclear. Here the authors show that activated MAIT cells induce an IFN-γ transcriptome in natural killer (NK) cells and enha

Externí odkaz: https://doaj.org/article/01f893fc7b8b403cadf95ab8ec274a3e

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Akademický článek

CRISPR/Cas9 mediated deletion of the adenosine A2A receptor enhances CAR T cell efficacy

Autor: Lauren Giuffrida, Kevin Sek, Melissa A. Henderson, Junyun Lai, Amanda X. Y. Chen, Deborah Meyran, Kirsten L. Todd, Emma V. Petley, Sherly Mardiana, Christina Mølck, Gregory D. Stewart, Benjamin J. Solomon, Ian A. Parish, Paul J. Neeson, Simon J. Harrison, Lev M. Kats, Imran G. House, Phillip K. Darcy, Paul A. Beavis

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)

Activation of the adenosine receptor A2AR is associated with suppression of T cell function in the tumor microenvironment. To overcome immunosuppression, here the authors show that CRISPR/Cas9 mediated deletion of A2AR enhances CAR T cell effector fu

Externí odkaz: https://doaj.org/article/483b1c1b715b445cad3cbef377ef8466

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Akademický článek

SPECTRAL PREPROCESSING FOR HYPERSPECTRAL REMOTE SENSING OF HEAVY METALS IN WATER

Autor: M. Lee, X.-Y. Chen, H.-C. Lee

Publikováno v: The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, Vol XLII-2-W13, Pp 1869-1873 (2019)

This study aims to investigate the feasibility of using hyperspectral remote sensing technique by visible-near infrared spectroradiometer (VNIR, FieldSpec HandHeld 2) for rapid water monitoring of heavy metal, followed by comparison of different spec

Externí odkaz: https://doaj.org/article/669c0a3c0df34ba3ae0b1bd3aeea072e

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