Zobrazeno 1 - 10
of 16
pro vyhledávání: '"X F Steven Zheng"'
Autor:
Yin-Lian Cha, Pin-Dong Li, Lin-Jing Yuan, Mei-Yin Zhang, Yao-Jun Zhang, Hui-Lan Rao, Hui-Zhong Zhang, X F Steven Zheng, Hui-Yun Wang
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0117493 (2015)
EIF4EBP1 acts as a crucial effector in mTOR signaling pathway. Studies have suggested that EIF4EBP1 plays a critical role in carcinogenesis. However, the clinical significance and biological role of EIF4EBP1 in hepatocellular carcinoma (HCC) have not
Externí odkaz:
https://doaj.org/article/ed059033fc78493aa0b38904ff664c98
Autor:
Hai-Shan Peng, Ming-Bin Liao, Mei-Yin Zhang, Yin Xie, Li Xu, Yao-Jun Zhang, X F Steven Zheng, Hui-Yun Wang, Yi-Fei Chen
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100814 (2014)
OBJECTIVES: Hypoxia is a common phenomenon in solid tumors, associated with chemotherapy and radiotherapy resistance, recurrence and metastasis. Hyperbaric oxygen (HBO) therapy can increase tissue oxygen pressure and content to prevent the resistance
Externí odkaz:
https://doaj.org/article/be5df4b7161644d3ae5a8527f0c14d6c
Publikováno v:
PLoS ONE, Vol 3, Iss 10, p e3520 (2008)
Telomere dysfunction is known to induce growth arrest (senescence) and cell death. However, the regulation of the senescence-death process is poorly understood. Here using a yeast dysfunctional telomere model cdc13-1, which carries a temperature sens
Externí odkaz:
https://doaj.org/article/967e4f1097ec4f79a0815ed88eacdf96
Autor:
Xiaowen Wang, Hong Zhang, Russell Sapio, Jun Yang, Justin Wong, Xin Zhang, Jessie Y. Guo, Sharon Pine, Holly Van Remmen, Hong Li, Eileen White, Chen Liu, Megerditch Kiledjian, Dimitri G. Pestov, X. F. Steven Zheng
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
The superoxide dismutase SOD1 is highly expressed in lung cancer but its role has not fully investigated yet. In this study, the authors demonstrate that SOD1 regulates ribosome biogenesis driving KRAS-driven lung tumorigenesis.
Externí odkaz:
https://doaj.org/article/10e3267362bc477794a94e24c0dbd94f
Nuclear SOD1 in Growth Control, Oxidative Stress Response, Amyotrophic Lateral Sclerosis, and Cancer
Publikováno v:
Antioxidants, Vol 11, Iss 2, p 427 (2022)
SOD1 is the major superoxide dismutase responsible for catalyzing dismutation of superoxide to hydrogen peroxide and molecular oxygen. It is well known as an essential antioxidant enzyme for maintaining cellular redox homeostasis. SOD1 dysregulation
Externí odkaz:
https://doaj.org/article/523b1ca6272647029171200174843325
Publikováno v:
Theranostics. 12:3518-3533
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d9e0c831aa714fbe816b18b4b22eb4e
https://doi.org/10.7150/thno.72581
https://doi.org/10.7150/thno.72581
Autor:
Chi Kwan Tsang, X. F. Steven Zheng
Publikováno v:
Molecular & Cellular Oncology, Vol 5, Iss 5 (2018)
Maintaining cellular redox is critical for growth, metabolism and survival in response to changing environments. How nutrients regulate this process is a long-standing fundamental question in cell biology. Our recent study revealed a conserved mechan
Externí odkaz:
https://doaj.org/article/e31fca13e7a64d15b14c812a6c4e0849
Autor:
Chi Kwan, Tsang, Qiongjie, Mi, Guangpu, Su, Gum, Hwa Lee, Xuemin, Xie, Gabriella, D'Arcangelo, Li'an, Huang, X F, Steven Zheng
Publikováno v:
Journal of Advanced Research.
Spontaneous recovery after CNS injury is often very limited and incomplete, leaving most stroke patients with permanent disability. Maf1 is known as a key growth suppressor in proliferating cells. However, its role in neuronal cells after stroke rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ed970df80dd8408008e01d7c51402b0
https://doi.org/10.1016/j.jare.2022.11.007
https://doi.org/10.1016/j.jare.2022.11.007
Publikováno v:
Eur J Cell Biol
Amino Acids are not only major nutrient sources, but also serve as chemical signals to control cellular growth. Rab1A recently emerged as a key component in amino acid sensing and signaling to activate the mTOR complex1 (mTORC1). In a recently publis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::070871ea185a5047e9f0835b1816daf1
https://doi.org/10.1016/j.ejcb.2022.151240
https://doi.org/10.1016/j.ejcb.2022.151240
Autor:
Yuehua, Wei, X F Steven, Zheng
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 759
Cell growth is highly regulated and its deregulation is related to many human diseases such as cancer. Nutritional cues stimulate cell growth through modulation of TOR (target of rapamycin) signaling pathway. At the center of this pathway is a large
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dceb5eb15c4ab889d993c39a10f4d1e7
https://pubmed.ncbi.nlm.nih.gov/21863495
https://pubmed.ncbi.nlm.nih.gov/21863495