Motor phenotypic alterations in TgDyrk1a transgenic mice implicate DYRK1A in Down syndrome motor dysfunction

Autor: M Martı́nez de Lagrán, X Altafaj, X Gallego, E Martı́, X Estivill, I Sahún, C Fillat, M Dierssen

Publikováno v: Neurobiology of Disease, Vol 15, Iss 1, Pp 132-142 (2004)

Motor deficits are among the most frequent impairments in Down syndrome (DS), but their neuropathological and molecular bases remain elusive. Here we investigate the motor profile of transgenic mice overexpressing Dyrk1a, Tg(Dyrk1a)1Cff (hereafter Tg

Externí odkaz: https://doaj.org/article/a36049fc537248e49cb6a53a1401e56f

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A new polymorphic locus, D7S411, isolated by cloning from preparative pulse-field gels is close to the mutation causing cystic fibrosis

Autor: M. Ramsay, B.J. Wainwright, M. Farrall, X. Estivill, H. Sutherland, M.-F. Ho, R. Davies, S. Halford, F. Tata, C. Wicking, N. Lench, I. Bauer, C. Ferec, P. Farndon, H. Kruyer, P. Stanier, R. Williamson, P.J. Scambler

Publikováno v: University of St Andrews CRIS

The mutation causing cystic fibrosis (CF) has been localized to the DNA sequence of 700 kb bounded by the loci identified by the markers pMP6d-9 (D7S399) and pJ3.11 (D7S8). A 560-kb fragment obtained after Sac II digestion of DNA from a cell line con

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd6a73dbfc3ca9dfbead02fa98614420
https://doi.org/10.1016/0888-7543(90)90446-2

Contents Vol. 123, 2008

Autor: M. Lanktree, C. Yau, C. Fawcett, W. Gu, S.J. Hebbring, C. Harvard, J.T. Jeon, J.C. Edberg, G. Füst, B.H. Rovin, H.M. Lachman, J.R. Vermeesch, S.W. Scherer, J.M. Kidd, R.A. Hegele, A. Tsalenko, G.H. Perry, S.P. Shah, H.H. Thygesen, M.E. Kalf, T. Nakajima, A.R. Brothman, G. Kaur, A.J. Sharp, R.H.A.M. Vossen, K. Buysse, R. Venkatachalam, K. De Preter, Á. Szilágyi, K.J. Kitzmiller, B. Poppe, X. Liu, A. Kimura, E.E. Eichler, Y. Satoh, A.P. Monaco, M.E.S. Lewis, A.C. Lionel, David Neil Cooper, C. Hopkins, M.J.L. Ligtenberg, R.F. Wintle, Jaimie Kelley, F. Hannes, D. FitzPatrick, M.A. Jobling, C.A. Ruivenkamp, C. Ruivenkamp, T.J. Aitman, C. Kumps, M. Kusenda, Caileigh Marshall, R.G. Walters, B.P. Tsao, T. Ptacek, F.H. Sharkey, C. Férec, C. Le Maréchal, A. Geurts van Kessel, J. Ragoussis, N. Takahashi, A J de Smith, E.K. Chung, M. Nei, L. Winchester, L. Armengol, H. Auer, M.H.B. Breuning, M. Kriek, J.T. den Dunnen, H. Katayama, E. Masson, E. Maher, N. Hoogerbrugge, C.Y. Yu, G. Froyen, B. Zhou, H.N. Nagaraja, N. Mehra, Y.L. Wu, N. Riendeau, R. Mendoza-Londono, J.J.A. Holden, E. Aston, W. Al-Sukhni, D.F. Newbury, C.C. Holmes, S. Gallinger, X. Li, Hildegard Kehrer-Sawatzki, G. Peters, P. Tsang, J.S. Beckmann, S. Tchatchou, H.J. Tanke, J.H. Lee, T. Azam, M. Nozawa, A.M. Moyer, Y. Yang, M. Kodaira, X. Estivill, A.I. Blakemore, D.J. Birmingham, P. Froguel, H. Riethman, J. Vandewalle, F. Speleman, L. Bruhn, L.A. Hebert, I. Johansson, M. Ingelman-Sundberg, R.P. Kuiper, Y. Qiao, P. Marynen, S.J. White, S.L. Savelli, B. Menten, A.J. Notini, J. Knijnenburg, E.J. Hollox, S. Goobie, D.N. Cooper, P. Bayrak-Toydemir, S.E. Antonarakis, G. Cutler, S. Mitchell, E. Rajcan-Separovic, J.A. Bailey, E. Aten, M. Bauters, A. Weuts, D.K. Bailey, H. Whitby, J.M. Chen, N.S. den Hollander, K. Chong, M. Shago, J.M. Craig, J. Sebat, P.D. Kassner, R.M. Weinshilboum, R. Rabionet, K. Szuhai, J.R. Lupski, T.J. Vyse, H. Van Esch, H. Kehrer-Sawatzki, J. Nevelsteen, B. Burwinkel, M. Fanciulli

Publikováno v: Cytogenetic and Genome Research. 123:I-IV

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f4e4d8bbf9cba28bce6a3c1fb08ed7b3
https://doi.org/10.1159/000209259