XP13512 [(+/-)-1-([(alpha-isobutanoyloxyethoxy)carbonyl] aminomethyl)-1-cyclohexane acetic acid], a novel gabapentin prodrug: I. Design, synthesis, enzymatic conversion to gabapentin, and transport by intestinal solute transporters.

Autor: C, Cundy Kenneth, Russell, Branch, Tania, Chernov-Rogan, Tracy, Dias, Too, Estrada, Karin, Hold, Kerry, Koller, Xiaoli, Liu, Adam, Mann, Matt, Panuwat, P, Raillard Stephen, Shubhra, Upadhyay, Q, Wu Quincey, Jia-Ning, Xiang, Hui, Yan, Noa, Zerangue, X, Zhou Cindy, W, Barrett Ronald, A, Gallop Mark

Publikováno v: The Journal of Pharmacology and Experimental Therapeutics; October 2004, Vol. 311 Issue: 1 p315-23, 9p