Pharmacokinetic Model of Tenofovir and Emtricitabine and Their Intracellular Metabolites in Patients in the ANRS 134-COPHAR 3 Trial Using Dose Records

Autor: Julie Bertrand, Aurélie Barrail-Tran, Lucie Fayette, Rada Savic, Cécile Goujard, Elina Teicher, Caroline Barau, Alain Pruvost, Anne-Marie Taburet, France Mentré, Céline Verstuyft, A. Barrail-Tran, A. Brunet, M.-J. Commoy, S. Couffin-Cadiergues, D. Descamps, X. Duval, C. Goujard, C. Le Guellec, F. Mentré, G. Nembot, A.-M. Taburet, B. Vrijens, •• Ajana, •• Aissi, •• Baclet, •• Besnier, •• Bollens, •• Boulanger, •• Brochier, •• Brunet, •• Chaix, •• Ciuchete, •• Ghosn, •• Duval, •• Ferret, •• Gaubin, •• Goujard, •• Girard, •• Kouadio, •• Lupin, •• Parienti, •• Parrinello, •• Poinçon de la Blanchardière, •• May, •• Marien, •• Medintzeff, •• Metivier, •• Mole, •• Molina, •• Nau, •• Ouazene, •• Pintado, •• Quertainmont, •• Ramani, •• Rami, •• Sellier, •• Simon, •• Talbi, •• Thoirain, •• Verdon, •• Trépo, •• Wassoumbou, •• Yazdanpanah, •• Barrail-Tran, •• Gagneux, •• Delhotal, •• Hoizey, •• Houdret, •• Leguellec, •• Peytavin, •• Poirier, •• Sauvageon, •• Taburet, •• André, •• Soulié, •• Calvez, •• Morand-Joubert, •• Harchi, •• Bocket, •• Mourez, •• Palmer, •• Pallier, •• Deschamps, •• Mazeron, •• Bolmann, •• Storto, •• Thanh Thuy, G. Unal, X. Panhard, R. Savic

Publikováno v: Antimicrobial Agents and Chemotherapy. 67

Tenofovir (TFV) and emtricitabine (FTC) are part of the recommended highly active antiretroviral therapy (ART). Both molecules show a large interindividual pharmacokinetic (PK) variability.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::79edc80bf1b79fa9ec9c15a7af7db223
https://doi.org/10.1128/aac.02339-18

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Escherichia coli bacteraemia in adults: age-related differences in clinical and bacteriological characteristics, and outcome

Autor: C, Roubaud Baudron, X, Panhard, O, Clermont, F, Mentré, B, Fantin, E, Denamur, A, Lefort, Florence, Tubach

Publikováno v: Epidemiol Infect

SUMMARYTo explore the specificities ofEscherichia colibacteraemia in the elderly, the demographic, clinical and bacteriological characteristics and in-hospital mortality rate of ‘young’ (18–64 years,n = 395), ‘old’ (65–79 years,n = 372) a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::641acbd47c5fd4ee7d4691a3fda51c4d
https://pubmed.ncbi.nlm.nih.gov/24559489

Influence of pharmacogenetics on indinavir disposition and short-term response in HIV patients initiating HAART

Autor: Julie, Bertrand, Jean-Marc, Treluyer, Xavière, Panhard, Agnes, Tran, Solange, Auleley, Elisabeth, Rey, Dominique, Salmon-Céron, Xavier, Duval, France, Mentré, X, Panhard

Publikováno v: European Journal of Clinical Pharmacology
European Journal of Clinical Pharmacology, Springer Verlag, 2009, 65 (7), pp.667-678. ⟨10.1007/s00228-009-0660-5⟩
European Journal of Clinical Pharmacology, Springer Verlag, 2009, 65 (7), pp.667-678. 〈10.1007/s00228-009-0660-5〉
European Journal of Clinical Pharmacology, Springer Verlag, 2009, 65 (7), pp.667-78. ⟨10.1007/s00228-009-0660-5⟩
European Journal of Clinical Pharmacology, Springer Verlag, 2009, 65 (7), pp.667-78. 〈10.1007/s00228-009-0660-5〉

International audience; AIMS: To assess the relationship between genetic polymorphisms and indinavir pharmacokinetic variability and to study the link between concentrations and short-term response or metabolic safety. METHODS: Forty protease inhibit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f823f741fa0ce8ce72e9aee66009971a
https://hal.archives-ouvertes.fr/hal-00534961/document

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