Zobrazeno 1 - 10
of 77
pro vyhledávání: '"X, Paliard"'
Autor:
L Shao, Donn M. Dennis, X Paliard, Allan E. Rettie, S Bowersox, MP Palme, L Lach, C Becker, A Choppin, I Irwin, P. Druzgala, Matthew G. McDonald
Publikováno v:
British Journal of Pharmacology. 158:1536-1547
Background and purpose: Tecarfarin (ATI-5923) is a novel vitamin K epoxide reductase inhibitor that is metabolized by esterase (mainly human carboxylesterase 2) to a single major metabolite, ATI-5900, in rats, dogs and humans. Tecarfarin is not signi
Publikováno v:
Cellular immunology, 135(2), 383-393. Academic Press Inc.
Interleukin (IL)-4 has been shown to be secreted simultaneously with IL-2 and interferon (IFN)-γ by the majority of CD4 + human T cell clones isolated and cultured using IL-2 as a growth factor. Moreover, IL-4 was found to be as efficient as IL-2 to
Autor:
A Y, Lee, W C, Manning, C L, Arian, N K, Polakos, J L, Barajas, J B, Ulmer, M, Houghton, X, Paliard
Publikováno v:
Hepatology (Baltimore, Md.). 31(6)
The immunology of hepatitis C virus (HCV) infection should be studied in the context of HCV antigen expression in the liver, because HCV primarily infects this organ. Indeed, the nature, function, and fate of T cells primed after antigen expression i
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 147(4)
CD4+ TCR-gamma delta+ T cells comprise a very small subset of TCR-gamma delta+ T cells. CD4+ TCR gamma delta+ T cell clones were established to study the phenotypical and functional characteristics of these cells. Thirty-four CD4+ TCR-gamma delta+ T
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Publikováno v:
European Journal of Immunology. 18:445-450
Human colostral secretory IgA (SIgA; predominantly present in dimeric of polymeric forms) induces receptors for the Fc portion of IgA (Fc alpha R) on cloned and noncloned human T cell lines. The binding of SIgA to its FcR was isotype specific, since
Publikováno v:
Nature. 335:642-644
CD4 and CD8 antigens are simultaneously expressed on most of the cortical thymocytes, that weakly express the T-cell antigen receptor(TCR)/CD3 complex1,2. Mature peripheral T cells, however, strongly express the TCR complex and are positive for eithe
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 143(5)
Analysis of Ag specificity of TRC-gamma delta+ T cells in humans has been hampered by the fact that cloned lines of these cells expanded in IL-2 generally display high NK-like cytotoxic activity. A TCR-gamma delta+ CTL clone, isolated in IL-4, strong
Autor:
X, Paliard, R, de Waal Malefijt, H, Yssel, D, Blanchard, I, Chrétien, J, Abrams, J, de Vries, H, Spits
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 141(3)
In the present study, we have investigated the ability of human T cells to secrete IL-2, IL-4, and IFN-gamma. IL-4 and IFN-gamma were quantified with enzymatic immunoassays and IL-2 with a biologic assay by using the murine IL-2-dependent cell line C
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 143(2)
IL-4 has been shown to act as a growth factor for human T cells. In addition, IL-4 can enhance CTL activity in MLC, but blocks IL-2 induced lymphokine activated killer cell activity in PBL. In our study, the cloning efficiencies, Ag-specific CTL acti