Výsledky vyhledávání - "Wynter J. Duncanson"

Flow of Tunable Elastic Microcapsules through Constrictions

Autor: Maria J. B. Moura, Ana Mehl, Marcio S. Carvalho, Wynter J. Duncanson, Jorge Avendaño, Debora Freitas do Nascimento

Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-7 (2017)
Scientific Reports

We design and fabricate elastically tunable monodisperse microcapsules using microfluidics and cross-linkable polydimethylsiloxane (PDMS). The overall stiffness of the microcapsules is governed by both the thickness and cross-link ratio of the polyme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b67f6f7440db63f97fce43b3acafc9da
http://link.springer.com/article/10.1038/s41598-017-11950-2

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Perfluoroalkyl-Functionalized Hyperbranched Polyglycerol as Pore Forming Agents and Supramolecular Hosts in Polymer Microspheres

Autor: Maximilian Zieringer, Wynter J. Duncanson, Rainer Haag, Olaf Wagner, David A. Weitz

Publikováno v: International Journal of Molecular Sciences, Vol 16, Iss 9, Pp 20183-20194 (2015)
International Journal of Molecular Sciences
Volume 16
Issue 9
Pages 20183-20194

Perfluoroalkyl-functionalized, hyperbranched polyglycerols that produce stable microbubbles are integrated into a microfluidic emulsion to create porous microspheres. In a previously-presented work a dendrimer with a perfluorinated shell was used. By

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1535ab5bb5b48aca169ee5a0d6a97317
https://doi.org/10.3390/ijms160920183

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Microfluidic Fabrication and Micromechanics of Permeable and Impermeable Elastomeric Microbubbles

Autor: Sahab Babaee, Thomas E. Kodger, Wynter J. Duncanson, Grant M. Gonzalez, Katia Bertoldi, David A. Weitz

Publikováno v: Langmuir. 31:3489-3493

We use droplet microfluidics to produce monodisperse elastomeric microbubbles consisting of gas encapsulated in a polydimethylsiloxane shell. These microbubbles withstand large, repeated deformations without rupture. We perform μN-scale compression

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8baebbc79ac22e7871902562be0865c
https://doi.org/10.1021/la504843p

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Surface modification of stainless steel for biomedical applications: Revisiting a century-old material

Autor: Helena S. Azevedo, Aliya Bekmurzayeva, Damira Kanayeva, Wynter J. Duncanson

Publikováno v: Materials scienceengineering. C, Materials for biological applications. 93

Stainless steel (SS) has been widely used as a material for fabricating cardiovascular stents/valves, orthopedic prosthesis, and other devices and implants used in biomedicine due to its malleability and resistance to corrosion and fatigue. Despite i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a224f57b32483be999301081b7d36018
https://pubmed.ncbi.nlm.nih.gov/30274039

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Targeted binding of PEG-lipid modified polymer ultrasound contrast agents with tiered surface architecture

Autor: Kelleny Oum, Margaret A. Wheatley, Joyce Wong, Wynter J. Duncanson, John R. Eisenbrey, Robin O. Cleveland

In order for site-directed polymer ultrasound contrast agents (UCAs) to provide acoustic enhancement at disease sites to distinguish normal tissue from diseased tissue, the surface of these agents must be functionalized with mixtures of grafted polym

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64057008f92fdac5e5fdc445e6bb678a
https://doi.org/10.1002/bit.22678

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Monodisperse Gas-Filled Microparticles from Reactions in Double Emulsions

Autor: Shin-Hyun Kim, David A. Weitz, Ho Cheung Shum, Alireza Abbaspourrad, Laura L. Adams, Wynter J. Duncanson

Publikováno v: ResearcherID

We present a strategy for preparing size-controlled gas-filled microparticles using two aqueous components that chemically react to produce the gas. We use a dual-bore microfluidic device to isolate the reactants of two gas-producing reactions until

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f275db07eb7a475de2a0a2c225cc476d
https://doi.org/10.1021/la300915p

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Targeted binding of PLA microparticles with lipid-PEG-tethered ligands

Autor: Joyce Wong, Kevin Hallock, Wynter J. Duncanson, Michael Figa, James A. Hamilton, Samuel Zalipsky

Publikováno v: Biomaterials. 28:4991-4999

Solid core polymeric particles are an attractive delivery vehicle as they can efficiently encapsulate drugs of different physical and chemical characteristics. However, the effective targeting of such particles for therapeutic purposes has been somew

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb03eecde0c764fa61588b03e9e0891c
https://doi.org/10.1016/j.biomaterials.2007.05.044

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Microfluidic fabrication of perfluorohexane-shelled double emulsions for controlled loading and acoustic-triggered release of hydrophilic agents

Autor: Jonathan A. Kopechek, Tyrone M. Porter, Wynter J. Duncanson, Laura R. Arriaga, David A. Weitz, W. Lloyd Ung

Publikováno v: Langmuir : the ACS journal of surfaces and colloids. 30(46)

The ability of low boiling point liquid perfluorocarbons (PFCs) to undergo a phase change from a liquid to a gas upon ultrasound irradiation makes PFC-based emulsions promising vehicles for triggered delivery of payloads. However, loading hydrophilic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e55f48d519a2699e78b2943aab48658
https://pubmed.ncbi.nlm.nih.gov/25340527

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Microfluidic fabrication of stable gas-filled microcapsules for acoustic contrast enhancement

Autor: Michael Rubinstein, Wynter J. Duncanson, Aleksandr P. Zhushma, Shin-Hyun Kim, Alireza Abbaspourrad, Natalia V. Lebedeva, Paul A. Dayton, Sujit S. Datta, David A. Weitz, Sergei S. Sheiko

Publikováno v: Langmuir : the ACS journal of surfaces and colloids. 29(40)

We introduce a facile approach for the production of gas-filled microcapsules designed to withstand high pressures. We exploit microfluidics to fabricate water-filled microcapsules that are then externally triggered to become gas-filled, thus making

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3980b620c8dbe41e79d228a15fb61e95
https://pubmed.ncbi.nlm.nih.gov/24066971

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Emulsion templating of poly(lactic acid) particles: droplet formation behavior

Autor: Wynter J. Duncanson, Goran T. Vladisavljevic, David A. Weitz, Ho Cheung Shum

Publikováno v: Langmuir

Monodisperse poly(DL-lactic acid) (PLA) particles of diameters between 11 and 121 mu m were fabricated in flow focusing glass microcapillary devices by evaporation of dichloromethane (DCM) from emulsion droplets at room temperature. The dispersed pha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2101676fdd2afe862fe1e1e8d5533673
https://pubmed.ncbi.nlm.nih.gov/22860633

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