Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Wyne P Lee"'
Autor:
Arna Katewa, Eric Suto, Jessica Hui, Jose Heredia, Jie Liang, Jason Hackney, Keith Anderson, Tuija M Alcantar, Natasha Bacarro, Debra Dunlap, Jeffrey Eastham, Andres Paler-Martinez, Xin Y Rairdan, Zora Modrusan, Wyne P Lee, Cary D Austin, Daniel Lafkas, Nico Ghilardi
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0244439 (2021)
Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease representing a serious unmet medical need. The disease is associated with the loss of self-tolerance and exaggerated B cell activation, resulting in autoantibody production and the fo
Externí odkaz:
https://doaj.org/article/ed0d04cf471f47d69accfbf3ee12f167
Autor:
Ganesh Kolumam, Xiumin Wu, Wyne P Lee, Jason A Hackney, Jose Zavala-Solorio, Vineela Gandham, Dimitry M Danilenko, Puneet Arora, Xiaoting Wang, Wenjun Ouyang
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170639 (2017)
Diabetic foot ulcers (DFU) are one of the major complications in type II diabetes patients and can result in amputation and morbidity. Although multiple approaches are used clinically to help wound closure, many patients still lack adequate treatment
Externí odkaz:
https://doaj.org/article/12da7ac249cf4cd88459569faf61f85e
Autor:
Arivazhagan Sambandam, Elaine Storm, Helen Tauc, Jason A. Hackney, David Garfield, Patrick Caplazi, John Liu, Juan Zhang, Hua Zhang, Jeff Duggan, Surinder Jeet, Sarah Gierke, Patrick Chang, Xiumin Wu, Robert Newman, Lucinda Tam, Tuija Alcantar, Lifen Wang, Meron Roose-Girma, Zora Modrusan, Wyne P. Lee, Heinrich Jasper, Frederic de Sauvage, Rajita Pappu
Publikováno v:
Heliyon, Vol 9, Iss 3, Pp e14238- (2023)
The ability of stem cells to rapidly proliferate and differentiate is integral to the steady-state maintenance of tissues with high turnover such as the blood and intestine. Mutations that alter these processes can cause primary immunodeficiencies, m
Externí odkaz:
https://doaj.org/article/5f0b411f56a24ccdae5dfc7e215eea4e
Autor:
Vivekananda Kedage, Diego Ellerman, Mingjian Fei, Wei-Ching Liang, Gu Zhang, Eric Cheng, Juan Zhang, Yongmei Chen, Haochu Huang, Wyne P. Lee, Yan Wu, Minhong Yan
Publikováno v:
mAbs, Vol 14, Iss 1 (2022)
While antibody-dependent cellular phagocytosis mediated by activating Fcγ receptor is a key mechanism underlying many antibody drugs, their full therapeutic activities can be restricted by the inhibitory Fcγ receptor IIB (FcγRIIB). Here, we descri
Externí odkaz:
https://doaj.org/article/a4637a431cdc4e5c801dd6e32b9072f3
Autor:
Katherine Bao, Juan Zhang, Alexis Scherl, James Ziai, Azi Hadadianpour, Daqi Xu, Christopher Dela Cruz, John Liu, Yuxin Liang, Lucinda Tam, Cesar A. Corzo, Merone Roose-Girma, Soren Warming, Zora Modrusan, Wyne P. Lee, Kam Hon Hoi, Ali A. Zarrin
Publikováno v:
The Journal of Immunology. 208:2632-2642
Genetic and environmental cues shape the evolution of the B cell Ig repertoire. Activation-induced cytidine deaminase (AID) is essential to generating Ig diversity through isotype class switching and somatic mutations, which then directly influence c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7df2e88b7d04fa4a050bba87261356c
https://doi.org/10.4049/jimmunol.2101193
https://doi.org/10.4049/jimmunol.2101193
Autor:
WeiYu Lin, Daqi Xu, Cary D. Austin, Patrick Caplazi, Kate Senger, Yonglian Sun, Surinder Jeet, Judy Young, Donnie Delarosa, Eric Suto, Zhiyu Huang, Juan Zhang, Donghong Yan, Cesar Corzo, Kai Barck, Sharmila Rajan, Carrie Looney, Vineela Gandham, Justin Lesch, Wei-Ching Liang, Elaine Mai, Hai Ngu, Navneet Ratti, Yongmei Chen, Dinah Misner, Tori Lin, Dimitry Danilenko, Paula Katavolos, Estelle Doudemont, Hirdesh Uppal, Jeffrey Eastham, Judy Mak, Patricia E. de Almeida, Katherine Bao, Azadeh Hadadianpour, Mary Keir, Richard A. D. Carano, Lauri Diehl, Min Xu, Yan Wu, Robby M. Weimer, Jason DeVoss, Wyne P. Lee, Mercedesz Balazs, Kevin Walsh, Kathila R. Alatsis, Flavius Martin, Ali A. Zarrin
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Colony-stimulating factor 1 (CSF1) and interleukin 34 (IL34) signal via the CSF1 receptor to regulate macrophage differentiation. Studies in IL34- or CSF1-deficient mice have revealed that IL34 function is limited to the central nervous system and sk
Externí odkaz:
https://doaj.org/article/f5bbd900f7f94b86b15fbd853c8ad352
Autor:
Napoleone Ferrara, Weiru Wang, Robert F. Kelley, Camellia Adams, Richard D. Carano, Lisa A. Damico-Beyer, Wyne P. Lee, Rashi Takkar, Jenny Yao, Racquel Corpuz, Kai Barck, Eric Suto, Peter Gribling, Leah Quintana, Robyn Clark, Suzy Clark, Nancy Y. Chiang, Terence Wong, Mary Coons, Mark Ultsch, Hong Xiang, Bing Li, Jianyong Wang, Cuiling Zhong
PDF file, 20K, Effects of 30D8 on 4T1 cell migration in vitro.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e863bc512bdec42f8a5f2f1aef17dca
https://doi.org/10.1158/1078-0432.22446066
https://doi.org/10.1158/1078-0432.22446066
Autor:
Napoleone Ferrara, Weiru Wang, Robert F. Kelley, Camellia Adams, Richard D. Carano, Lisa A. Damico-Beyer, Wyne P. Lee, Rashi Takkar, Jenny Yao, Racquel Corpuz, Kai Barck, Eric Suto, Peter Gribling, Leah Quintana, Robyn Clark, Suzy Clark, Nancy Y. Chiang, Terence Wong, Mary Coons, Mark Ultsch, Hong Xiang, Bing Li, Jianyong Wang, Cuiling Zhong
PDF file, 239K, Intervention studies in the laser-induced choroidal neovascularization (CNV) model.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31c2c93f91f7b9948998d104cc651807
https://doi.org/10.1158/1078-0432.22446063.v1
https://doi.org/10.1158/1078-0432.22446063.v1
Autor:
Napoleone Ferrara, Weiru Wang, Robert F. Kelley, Camellia Adams, Richard D. Carano, Lisa A. Damico-Beyer, Wyne P. Lee, Rashi Takkar, Jenny Yao, Racquel Corpuz, Kai Barck, Eric Suto, Peter Gribling, Leah Quintana, Robyn Clark, Suzy Clark, Nancy Y. Chiang, Terence Wong, Mary Coons, Mark Ultsch, Hong Xiang, Bing Li, Jianyong Wang, Cuiling Zhong
PDF file, 28K, Effects of 30D8 on CXCL12 and VEGF serum levels in HM7 tumor bearing mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::888187c59869a5ec3f76270b83fad4f1
https://doi.org/10.1158/1078-0432.22446057.v1
https://doi.org/10.1158/1078-0432.22446057.v1
Autor:
Napoleone Ferrara, Weiru Wang, Robert F. Kelley, Camellia Adams, Richard D. Carano, Lisa A. Damico-Beyer, Wyne P. Lee, Rashi Takkar, Jenny Yao, Racquel Corpuz, Kai Barck, Eric Suto, Peter Gribling, Leah Quintana, Robyn Clark, Suzy Clark, Nancy Y. Chiang, Terence Wong, Mary Coons, Mark Ultsch, Hong Xiang, Bing Li, Jianyong Wang, Cuiling Zhong
PDF file, 78K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb3ca56db6c5b8ecd32c560a8f5c5884
https://doi.org/10.1158/1078-0432.22446051
https://doi.org/10.1158/1078-0432.22446051