Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Wylie, David C."'
Publikováno v:
Drug Delivery System. 20:620-634
The hepatitis C virus (HCV) is currently estimated to infect over 270 million people worldwide, with up to 4 million people newly infected each year. It is the leading cause of chronic liver disease and the most common reason for liver transplantatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57661239ec1e6cf6604afde01cd3eb3c
https://doi.org/10.2745/dds.20.620
https://doi.org/10.2745/dds.20.620
Autor:
Guodong Chen, Barbara Twarowska, Tattanahali L. Nagabhushan, Vellekamp Gary J, Shihong Wang, Birendra N. Pramanik, John T. Tang, Urooj A. Mirza, Wylie David C, Fred W. Porter, Yan-Hui Liu
Publikováno v:
International Journal of Mass Spectrometry. 226:55-69
The clinical application of recombinant adenoviruses as vectors for gene therapy brings about the need to develop new analytical methodologies for monitoring the quality of the viral production as well as establishing structure–function relationshi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bce8627ee9ed177f4cea10926698ad16
https://doi.org/10.1016/s1387-3806(02)00975-2
https://doi.org/10.1016/s1387-3806(02)00975-2
Autor:
Collette Cutler, Marcio Voloch, Susan Cannon-Carlson, Seoju Lee, Yan-Hui Liu, Wylie David C, Birenda N. Pramanik
Publikováno v:
Pharmaceutical Research. 18:1354-1360
Purpose. Pegylation of therapeutic protein usually results in a mixture of monopegylated proteins with differing sites of modification. With rh-interferon-α2A pegylation, we have found that this heterogeneity includes two classes of pegylation site
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f192f23ca503eb54494460d261fb03cc
https://doi.org/10.1023/a:1013006515587
https://doi.org/10.1023/a:1013006515587
Autor:
James Bausch, Mollie N. Pflumm, Anthony Tsarbopoulos, Stephen Gruber, Suman T. Patel, Wylie David C, Birendra N. Pramanik
Publikováno v:
Pharmaceutical Research. 14:833-836
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::551409d069d156c581e8235fd081f155
https://doi.org/10.1023/a:1012127228239
https://doi.org/10.1023/a:1012127228239
Autor:
Stuart Cox, Susan Cannon-Carlson, Sheri Bradshaw, Grace Michael, Wylie David C, Jeffrey Chapman, Ronald Bordens, Brassard Diana L, Marcio Voloch, Constance Cullen, Jeffrey Spond, Marc DeLorenzo, Stephen R. Indelicato, Seoju Lee
Publikováno v:
The Journal of biological chemistry. 280(8)
Therapeutic pegylated interferon-alphas (IFN-alpha) are mixtures of positional isomers that have been monopegylated at specific sites on the core IFN-alpha molecule. The pegylation results in lower in vitro specific activity associated with the core
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a95493b3422b2209a52a781f7aad5a0
https://pubmed.ncbi.nlm.nih.gov/15596441
https://pubmed.ncbi.nlm.nih.gov/15596441
Autor:
Yung S. Tsao, Marcio Voloch, Liang Deng, Brittany Charlotte Larkin, Wai Lam Wong Ling, Wylie David C
Publikováno v:
Biotechnology and applied biochemistry. 40(Pt 3)
The presence and absence of inter-heavy-chain disulphide linkages contribute to the existence of the tetrameric (H(2)L(2)) and half (HL) human IgG molecules, respectively. Reduced effector response in the human IgG4 subclass presents an alternative t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::823a7747110c40cdb12b26877d0c984a
https://pubmed.ncbi.nlm.nih.gov/14979869
https://pubmed.ncbi.nlm.nih.gov/14979869
Autor:
Larry Bondoc, Vellekamp Gary J, Marcio Voloch, Suganto Sutjipto, Susan Cannon-Carlson, Wylie David C, Frei Andreas, Shaobin Zhuang, Yan-Hui Liu, Frederick William Porter, Collette M. Cutler, John T. Tang
Publikováno v:
Human gene therapy. 12(15)
Empty capsids from adenovirus, that is, virus particles lacking DNA, are well documented in the published literature. They can be separated from complete virus by CsCl density gradient centrifugation. Here we characterize the presence of empty capsid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8fee92db506daed2a8dc2a7ff87b564
https://pubmed.ncbi.nlm.nih.gov/11589834
https://pubmed.ncbi.nlm.nih.gov/11589834
Autor:
John Chu-Tay Tang, Tattanahalli L. Nagabhushan, Jeff Varnerin, Susan Cannon-Carlson, Birendra N. Pramanik, Anthony Tsarbopoulos, Wylie David C
Publikováno v:
Journal of mass spectrometry : JMS. 35(3)
Interleukin 13 (IL-13), a member of the a-helical family of cytokines, has approximately 30% primary sequence homology with IL-4 and shares a common receptor component. The biologically active rhIL-13 is monomeric and non-glycosylated, and contains t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c83059c3ce0e6cdd5cd041d3f956ad9
https://pubmed.ncbi.nlm.nih.gov/10767776
https://pubmed.ncbi.nlm.nih.gov/10767776
Autor:
Walker, John M., Smales, C. Mark, James, David C., Wylie, David C., Voloch, Marcio, Seoju Lee, Yan-Hui Liu, Cutler, Collette, Larkin, Brittany, Cannon-Carlson, Susan
Publikováno v:
Therapeutic Proteins; 2005, p337-348, 12p