A Genome-Wide Helicobacter pylori Morphology Screen Uncovers a Membrane-Spanning Helical Cell Shape Complex

Autor: Yang, Desirée C., Blair, Kris M., Taylor, Jennifer A., Petersen, Timothy W., Sessler, Tate, Tull, Christina M., Leverich, Christina K., Collar, Amanda L., Wyckoff, Timna J., Biboy, Jacob, Vollmer, Waldemar, Salama, Nina R.

Evident in its name, the gastric pathogen Helicobacter pylori has a helical cell morphology which facilitates efficient colonization of the human stomach. An improved light-focusing strategy allowed us to robustly distinguish even subtle perturbation

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https://europepmc.org/articles/PMC6597387/

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A Genome-Wide Helicobacter pylori Morphology Screen Uncovers a Membrane-Spanning Helical Cell Shape Complex.

Autor: Yang DC; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Blair KM; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.; Molecular and Cellular Biology Ph.D. Program, University of Washington, Seattle, Washington, USA., Taylor JA; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.; Department of Microbiology, University of Washington School of Medicine, Seattle, Washington, USA., Petersen TW; BD Biosciences, Seattle, Washington, USA., Sessler T; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Tull CM; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Leverich CK; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Collar AL; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Wyckoff TJ; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.; Division of Science and Mathematics, University of Minnesota, Morris, Minnesota, USA., Biboy J; Centre for Bacterial Cell Biology, Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle upon Tyne, United Kingdom., Vollmer W; Centre for Bacterial Cell Biology, Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle upon Tyne, United Kingdom., Salama NR; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA nsalama@fredhutch.org.; Molecular and Cellular Biology Ph.D. Program, University of Washington, Seattle, Washington, USA.; Department of Microbiology, University of Washington School of Medicine, Seattle, Washington, USA.

Publikováno v: Journal of bacteriology [J Bacteriol] 2019 Jun 21; Vol. 201 (14). Date of Electronic Publication: 2019 Jun 21 (Print Publication: 2019).

Alginate is not a significant component of the extracellular polysaccharide matrix of PA14 and PAO1 Pseudomonas aeruginosa biofilms.

Autor: Wozniak DJ; Department of Civil and Environmental Engineering, Northwestern University, Evanston, IL 60208, USA., Wyckoff TJ, Starkey M, Keyser R, Azadi P, O'Toole GA, Parsek MR

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2003 Jun 24; Vol. 100 (13), pp. 7907-12. Date of Electronic Publication: 2003 Jun 16.