Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Wyatt R. Hack"'
Autor:
John C. Crabbe, Angela R. Ozburn, Robert J. Hitzemann, Stephanie E. Spence, Wyatt R. Hack, Jason P. Schlumbohm, Pamela Metten
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 4, Iss , Pp 100061- (2020)
Alcohol use disorders (AUDs) are prevalent, and are characterized by binge-like drinking, defined by patterns of focused drinking where dosages ingested in 2–4 h reach intoxicating blood alcohol levels (BALs). Current medications are few and com
Externí odkaz:
https://doaj.org/article/932849e6259a4bc9b698711fb648c549
Autor:
John C. Crabbe, Pamela Metten, Antonia M. Savarese, Angela R. Ozburn, Jason P. Schlumbohm, Stephanie E. Spence, Wyatt R. Hack
Publikováno v:
Brain Sciences, Vol 9, Iss 1, p 2 (2019)
Two independent lines of High Drinking in the Dark (HDID-1, HDID-2) mice have been bred to reach high blood alcohol levels after a short period of binge-like ethanol drinking. Male mice of both lines were shown to have reduced sensitivity to develop
Externí odkaz:
https://doaj.org/article/c76b96e7c61040148f41afe1a2e5fb6f
Autor:
Angela R. Ozburn, Felix Hausch, Hazel Hunt, John C. Crabbe, Michael Bauder, Kathryn LeMoine, Jason P. Schlumbohm, Pamela Metten, Antonia Savarese, Wyatt R. Hack
Publikováno v:
Alcohol Clin Exp Res
BACKGROUND: Chronic alcohol exposure can alter glucocorticoid receptor (GR) function in some brain areas that promotes escalated and compulsive-like alcohol intake. GR antagonism can prevent dependence-induced escalation in drinking, but very little
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::780eb87d45c889c7921aaf6d915e96a2
https://doi.org/10.1111/acer.14318
https://doi.org/10.1111/acer.14318
Publikováno v:
Addict Biol
We have modelled genetic risk for binge-like drinking by selectively breeding High Drinking in the Dark-1 and −2 (HDID-1 and HDID-2) mice for their propensity to reach intoxicating blood alcohol levels (BALs) after binge-like drinking in a single b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3851d5363bc9ebd158dc1f5265fed3c1
https://doi.org/10.1111/adb.13074
https://doi.org/10.1111/adb.13074
Autor:
Angela R. Ozburn, John C. Crabbe, Pamela Metten, Antonia Savarese, Jason P. Schlumbohm, Stephanie E. Spence, Wyatt R. Hack
Publikováno v:
Brain Sciences
Brain Sciences, Vol 9, Iss 1, p 2 (2019)
Volume 9
Issue 1
Brain Sciences, Vol 9, Iss 1, p 2 (2019)
Volume 9
Issue 1
Two independent lines of High Drinking in the Dark (HDID-1, HDID-2) mice have been bred to reach high blood alcohol levels after a short period of binge-like ethanol drinking. Male mice of both lines were shown to have reduced sensitivity to develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6b2253819c60084cd61d722c3ad9325
http://europepmc.org/articles/PMC6356868
http://europepmc.org/articles/PMC6356868
Autor:
Pamela Metten, K. Matthew Lattal, John C. Crabbe, Jason P. Schlumbohm, Amanda M. Barkley-Levenson, Wyatt R. Hack
Publikováno v:
Alcohol. 52:25-32
The comorbidity of substance- and alcohol-use disorders (AUD) with other psychiatric conditions, especially those related to stress such as post-traumatic stress disorder (PTSD), is well-established. Binge-like intoxication is thought to be a crucial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92e993c2c2cbbe3637d8d347d9cb3396
https://doi.org/10.1016/j.alcohol.2016.01.004
https://doi.org/10.1016/j.alcohol.2016.01.004
Autor:
Jason P. Schlumbohm, Angela R. Ozburn, John C. Crabbe, Robert Hitzemann, Pamela Metten, Wyatt R. Hack, Stephanie E. Spence
Publikováno v:
Brain, Behavior, & Immunity-Health
Brain, Behavior, & Immunity-Health, Vol 4, Iss, Pp 100061-(2020)
Brain, Behavior, & Immunity-Health, Vol 4, Iss, Pp 100061-(2020)
Alcohol use disorders (AUDs) are prevalent, and are characterized by binge-like drinking, defined by patterns of focused drinking where dosages ingested in 2–4 h reach intoxicating blood alcohol levels (BALs). Current medications are few and com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::545e35a76cb1e05923f987d862178a7a
https://doi.org/10.1016/j.bbih.2020.100061
https://doi.org/10.1016/j.bbih.2020.100061
Autor:
Lawrence C. Huang, John C. Crabbe, Jason P. Schlumbohm, Gian D. Greenberg, Wyatt R. Hack, Pamela Metten, Stephanie E. Spence
Publikováno v:
Alcohol (Fayetteville, N.Y.). 68
Despite acceptance that risk for alcohol-use disorder (AUD) has a large genetic component, the identification of genes underlying various components of risk for AUD has been hampered in humans, in part by the heterogeneity of expression of the phenot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75ad50f6836decd5f7e9b12ef981290d
https://pubmed.ncbi.nlm.nih.gov/29427828
https://pubmed.ncbi.nlm.nih.gov/29427828
Autor:
Angela R. Ozburn, Jason P. Schlumbohm, John C. Crabbe, Lawrence C. Huang, Amanda M. Barkley-Levenson, Stephanie E. Spence, Wyatt R. Hack, Pamela Metten
Publikováno v:
Pharmacology, biochemistry, and behavior. 160
Background There is a serious public health need for better understanding of alcohol use disorder disease mechanisms and for improved treatments. At this writing, only three drugs are approved by the Food and Drug Administration as medications to tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::772da906066c7f6eda3ddac873e13fde
https://pubmed.ncbi.nlm.nih.gov/28827047
https://pubmed.ncbi.nlm.nih.gov/28827047