Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Wyatt Byrd"'
Publikováno v:
Veterinary Microbiology. 211:180-188
We previously developed attenuated rabbit enteropathogenic E. coli (rEPEC) strains which are effective oral vaccines against their parent pathogens by deleting le r, a global regulator of virulence genes. To use these strains as orally administered v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f22246f87a34aedf124048eb1b916b92
https://doi.org/10.1016/j.vetmic.2017.10.006
https://doi.org/10.1016/j.vetmic.2017.10.006
Autor:
Edgar C. Boedeker, Wyatt Byrd
Publikováno v:
Veterinary Immunology and Immunopathology. 152:57-67
Although enterotoxigenic Escherichia coli (ETEC) infections are important causes of infantile and traveler's diarrhea there is no licensed vaccine available for those at-risk. Our goal is to develop a safe, live attenuated ETEC vaccine. We used an at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::260a90f82835489a5dcaf7071c59bbf9
https://doi.org/10.1016/j.vetimm.2012.10.001
https://doi.org/10.1016/j.vetimm.2012.10.001
Autor:
Edgar C. Boedeker, Wyatt Byrd, John Scott Wilbur, Hannah E. Ledvina, Gayatri Vedantam, Michael W. Riggs, V. K. Viswanathan, Shylaja Ramamurthy, Khaldoon Khirfan
Publikováno v:
Infection and immunity. 83(3)
Attaching and effacing (A/E) pathogens adhere intimately to intestinal enterocytes and efface brush border microvilli. A key virulence strategy of A/E pathogens is the type III secretion system (T3SS)-mediated delivery of effector proteins into host
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3a464a55740218a2414ea3cb4188d63
https://pubmed.ncbi.nlm.nih.gov/25561713
https://pubmed.ncbi.nlm.nih.gov/25561713
Autor:
Frederick J. Cassels, Wyatt Byrd
Publikováno v:
Vaccine. 21:1884-1893
Mice (BALB/c) were intranasally (IN) and intragastrically (IG) administered the ETEC colonization factors (CF), CFA/I and CS6, with and without the R192G mutant heat-labile enterotoxin (mLT), and immunogenicity and efficacy measured. The IN administr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c73b0a2eb84a285a1289063c993c72
https://doi.org/10.1016/s0264-410x(03)00014-8
https://doi.org/10.1016/s0264-410x(03)00014-8
Autor:
Anne Morris Hooke, Wyatt Byrd
Publikováno v:
Infection and Immunity. 65:2206-2210
Temperature-sensitive mutants of Actinobacillus pleuropneumoniae 4074, serotype 1, were isolated after treatment with nitrosoguanidine and enrichment with penicillin and D-cycloserine. Of the four temperature-sensitive mutants evaluated in mice, one
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4038ba116c967b36943ad35f0a0ecb7d
https://doi.org/10.1128/iai.65.6.2206-2210.1997
https://doi.org/10.1128/iai.65.6.2206-2210.1997
Publikováno v:
Infection and immunity. 79(4)
Previously, our laboratories reported that zinc inhibited expression of several important virulence factors in enteropathogenic Escherichia coli (EPEC) and reduced EPEC-induced intestinal damage in vivo . Since EPEC is genetically related to Shiga-to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e6a03079713324a8277dfcb27f22ad5
https://pubmed.ncbi.nlm.nih.gov/21245267
https://pubmed.ncbi.nlm.nih.gov/21245267
Publikováno v:
Veterinary Immunology and Immunopathology. 34:307-324
In an attempt to protect pigs against swine pleuropneumonia induced by Actinobacillus pleuropneumoniae (SPAP) by neutralizing the effects of three virulence factors of A. pleuropneumoniae--the capsular polysaccharide (CP), the lipopolysaccharide (LPS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0151b5826c49d2de20594dedefd73e2a
https://doi.org/10.1016/0165-2427(92)90172-m
https://doi.org/10.1016/0165-2427(92)90172-m
Autor:
Frederick J. Cassels, Wyatt Byrd
Publikováno v:
Microbiology (Reading, England). 152(Pt 3)
The aim of this study was to measure serum and mucosal antibody responses following intranasal administration of biodegradable poly(dl-lactide-co-glycolide) (PLGA) microspheres loaded with the CS3 colonization factor isolated from enterotoxigenicEsch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff6dcb6ad5203a3eec1ab0266f72d81e
https://pubmed.ncbi.nlm.nih.gov/16514157
https://pubmed.ncbi.nlm.nih.gov/16514157
Autor:
Frederick J. Cassels, Wyatt Byrd
Publikováno v:
FEMS immunology and medical microbiology. 46(2)
The immunogenicity induced in BALB/c mice following intranasal challenge with a viable nonlethal dose (1.2 x 10(8) CFU) of enterotoxigenic Escherichia coli (ETEC) strain E23477A (O139:H28:CS1:CS3:LT+:ST+) was studied over a 140-day period. Serum IgG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::388fcda7495c3a15dbcc63baf5fc2427
https://pubmed.ncbi.nlm.nih.gov/16487308
https://pubmed.ncbi.nlm.nih.gov/16487308
Autor:
Wyatt Byrd, Frederick J. Cassels
Publikováno v:
Vaccine. 24(9)
Mice were intranasally administered enterotoxigenic Escherichia coli colonization factor CS6 encapsulated in poly(DL-lactide-co-glycolide) microspheres (CS6-PLG), with immune response measured and compared to that of similarly administered native CS6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc96f138ff351d614177a93140a20ef1
https://pubmed.ncbi.nlm.nih.gov/16233937
https://pubmed.ncbi.nlm.nih.gov/16233937