Estrogen receptor expression activates the transcriptional and growth-inhibitory response to retinoids without enhanced retinoic acid receptor alpha expression

Autor: Rosenauer A, Clara NERVI, Davison K, Ww, Lamph, Mader S, Wh, Miller Jr

Publikováno v: Europe PubMed Central

Estrogen receptor (ER)-positive human breast cancer cells are hormonally regulated and are inhibited by retinoids, whereas most ER-negative breast cancer cells are not. Here, we compared retinoid-induced transcriptional activation and growth inhibiti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::756678e3dfca48924461c888f14675fb
https://pubmed.ncbi.nlm.nih.gov/9823320

Repression of exogenous gene expression by the retinoic acid target gene G0S2.

Autor: Ma T; Department of Pharmacology and Toxicology, Geisel School of Medicine at Dartmouth, Hanover, NH 03755, USA., Dong JP, Sekula DJ, Fei DL, Lamph WW, Henderson M, Lu Y, Blumen S, Freemantle SJ, Dmitrovsky E

Publikováno v: International journal of oncology [Int J Oncol] 2013 May; Vol. 42 (5), pp. 1743-53. Date of Electronic Publication: 2013 Mar 28.

Rexinoid-induced expression of IGFBP-6 requires RARbeta-dependent permissive cooperation of retinoid receptors and AP-1.

Autor: Uray IP; Breast Cancer Center and Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030 and Ligand Pharmaceuticals Ltd., San Diego, California 92121; Breast Cancer Center and Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030 and Ligand Pharmaceuticals Ltd., San Diego, California 92121., Shen Q; Breast Cancer Center and Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030 and Ligand Pharmaceuticals Ltd., San Diego, California 92121; Breast Cancer Center and Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030 and Ligand Pharmaceuticals Ltd., San Diego, California 92121., Seo HS; Breast Cancer Center and Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030 and Ligand Pharmaceuticals Ltd., San Diego, California 92121., Kim H; Breast Cancer Center and Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030 and Ligand Pharmaceuticals Ltd., San Diego, California 92121., Lamph WW; Breast Cancer Center and Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030 and Ligand Pharmaceuticals Ltd., San Diego, California 92121., Bissonnette RP; Breast Cancer Center and Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030 and Ligand Pharmaceuticals Ltd., San Diego, California 92121., Brown PH; Breast Cancer Center and Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030 and Ligand Pharmaceuticals Ltd., San Diego, California 92121; Breast Cancer Center and Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030 and Ligand Pharmaceuticals Ltd., San Diego, California 92121. Electronic address: pbrown@breastcenter.tmc.edu.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2009 Jan 02; Vol. 284 (1), pp. 345-353. Date of Electronic Publication: 2008 Oct 28.

Prevention and treatment of experimental estrogen receptor-negative mammary carcinogenesis by the synthetic triterpenoid CDDO-methyl Ester and the rexinoid LG100268.

Autor: Liby K; Department of Pharmacology, Dartmouth Medical School, Hanover, NH 03755, USA. karen.liby@darthmouth.edu, Risingsong R, Royce DB, Williams CR, Yore MM, Honda T, Gribble GW, Lamph WW, Vannini N, Sogno I, Albini A, Sporn MB

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2008 Jul 15; Vol. 14 (14), pp. 4556-63.

The rexinoid, bexarotene, prevents the development of premalignant lesions in MMTV-erbB2 mice.

Autor: Li Y; Breast Center, Department of Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA., Zhang Y, Hill J, Kim HT, Shen Q, Bissonnette RP, Lamph WW, Brown PH

Publikováno v: British journal of cancer [Br J Cancer] 2008 Apr 22; Vol. 98 (8), pp. 1380-8. Date of Electronic Publication: 2008 Mar 25.