Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Wuzhou Wan"'
Autor:
Ning Zhang, Guoguang Ying, Dalong Ma, Xiangjun Sun, De Yang, Ronghua Sun, Wuzhou Wan, Min Wu, Jingna Wang, Ying Liu
High expression of 3-phosphoinositide–dependent protein kinase-1 (PDK1) has been detected in various invasive cancers. In the current study, we investigated its role in cancer cell migration and experimental metastasis. Down-regulation of PDK1 expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e62aa3883a860f09f90ec54506a6109
https://doi.org/10.1158/1541-7786.c.6542208.v1
https://doi.org/10.1158/1541-7786.c.6542208.v1
Autor:
Ning Zhang, Guoguang Ying, Dalong Ma, Xiangjun Sun, De Yang, Ronghua Sun, Wuzhou Wan, Min Wu, Jingna Wang, Ying Liu
Supplementary Data from Down-Regulation of 3-Phosphoinositide–Dependent Protein Kinase-1 Levels Inhibits Migration and Experimental Metastasis of Human Breast Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5af36f3a6aa55d1fa3356d273927c59e
https://doi.org/10.1158/1541-7786.22518969.v1
https://doi.org/10.1158/1541-7786.22518969.v1
Autor:
Michail S Lionakis, Brett G Fischer, Jean K Lim, Muthulekha Swamydas, Wuzhou Wan, Chyi-Chia Richard Lee, Jeffrey I Cohen, Phillip Scheinberg, Ji-Liang Gao, Philip M Murphy
Publikováno v:
PLoS Pathogens, Vol 8, Iss 8, p e1002865 (2012)
Invasive candidiasis is the 4(th) leading cause of nosocomial bloodstream infection in the US with mortality that exceeds 40% despite administration of antifungal therapy; neutropenia is a major risk factor for poor outcome after invasive candidiasis
Externí odkaz:
https://doaj.org/article/7908d48573cf4eff95fe5b1bf9ff3b28
Autor:
Helton C. Santiago, Joseph D. Weaver, Victoria Hoffman, Wuzhou Wan, Ana Paula M. P. Marino, Ester Roffê, Philip M. Murphy, Fernanda Fortes de Araujo
Publikováno v:
Infection and Immunity. 84:1123-1136
Infectious agents are often considered potential triggers of chronic inflammatory disease, including autoimmunity; however, direct evidence is usually lacking. Here we show that following control of acute infection of mice with the myotropic Colombia
Autor:
Michail S. Lionakis, Muthulekha Swamydas, Stasia A. Anderson, Ana Paula M. P. Marino, Philip M. Murphy, Qian Liu, Wuzhou Wan
Publikováno v:
Cardiovascular Research. 106:478-487
Aims Atypical chemokine receptor 1 (Ackr1; previously known as the Duffy antigen receptor for chemokines or Darc) is thought to regulate acute inflammatory responses in part by scavenging inflammatory CC and CXC chemokines; however, evidence for a ro
Autor:
Philip M. Murphy, Theo S. Plantinga, Jean K. Lim, Martin Jaeger, Muthulekha Swamydas, Ji Liang Gao, John C. Yang, Constantinos M. Mikelis, Barbara D. Alexander, John R. Perfect, Chyi-Chia Richard Lee, Andrius Masedunskas, Brett G. Fischer, Wuzhou Wan, Nathaniel M. Green, Greg M. Laird, Bart Jan Kullberg, Melissa D. Johnson, Robert T. Wheeler, Michail S. Lionakis, Roberto Weigert, Aymeric Rivollier, Mihai G. Netea
Publikováno v:
Journal of Clinical Investigation, 123, 5035-51
Journal of Clinical Investigation, 123, 12, pp. 5035-51
Journal of Clinical Investigation, 123, 12, pp. 5035-51
Contains fulltext : 125417.pdf (Publisher’s version ) (Open Access) Systemic Candida albicans infection causes high morbidity and mortality and is associated with neutropenia; however, the roles of other innate immune cells in pathogenesis are poor
Autor:
Philip M. Murphy, Wuzhou Wan
Publikováno v:
Archivum Immunologiae et Therapiae Experimentalis. 61:1-14
Atherosclerosis is a chronic inflammatory and metabolic disorder affecting large and medium-sized arteries, and the leading cause of mortality worldwide. The pathogenesis of atherosclerosis involves accumulation of lipids and leukocytes in the intima
Publikováno v:
Cardiovascular Research. 97:580-588
Recent evidence suggests that both Ccr7 and its ligands, Ccl19 and Ccl21, are present in mouse and human atherosclerotic plaques; however, the role of Ccr7 in atherogenesis is still controversial. Here, we addressed this question by using the classic
Autor:
Liron Gibbs-Bar, Gregory S. Shelness, Ilana Rogachev, Daniel Castranova, Liran Carmel, Kenna Shaw, Josette Ungos, Moshe Grunspan, Van N. Pham, Tom T. Chen, Oded Mayseless, Yona Ely, Steven A. Farber, Philip M. Murphy, Carmen M. Warren, Brant M. Weinstein, Wuzhou Wan, Guy Malkinson, Gabriella Allmog, Kameha R. Kidd, M. Luisa Iruela-Arispe, Karina Yaniv, Brigid D. Lo, Inbal Avraham-Davidi
Publikováno v:
Nature Medicine. 18:967-973
Despite the clear major contribution of hyperlipidemia to the prevalence of cardiovascular disease in the developed world, the direct effects of lipoproteins on endothelial cells have remained obscure and are under debate. Here we report a previously
Autor:
Aymeric Rivollier, Michail S. Lionakis, Jean K. Lim, David H. McDermott, Wuzhou Wan, Philip M. Murphy, Brian L. Kelsall, Joshua M. Farber
Publikováno v:
Circulation Research. 109:374-381
Rationale: The chemokine receptor Ccr6 is a G-protein–coupled receptor expressed on various types of leukocytes identified in mouse atherosclerotic lesions. Recent evidence suggests that both CCR6 and its ligand CCL20 are also present in human athe