Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Wuzhen Chen"'
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Neoadjuvant chemotherapy (NAC) for breast cancer enables pathological complete response (pCR) in patients initially diagnosed with axillary lymph node metastases, potentially obviating the need for axillary lymph node dissection (
Externí odkaz:
https://doaj.org/article/6d8fc76b8fbb41eaacb2a35c7bb93620
Autor:
Shan Fang, Wenjie Xia, Haibo Zhang, Chao Ni, Jun Wu, Qiuping Mo, Mengjie Jiang, Dandan Guan, Hongjun Yuan, Wuzhen Chen
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
PurposeThis study aimed to develop and validate a clinicopathological model to predict pathological complete response (pCR) to neoadjuvant chemotherapy (NAC) in breast cancer patients and identify key prognostic factors.MethodsThis retrospective stud
Externí odkaz:
https://doaj.org/article/64275c0e49284f3c87af52270d3367a1
Autor:
Wenjie Xia, Wuzhen Chen, Chao Ni, Xuli Meng, Jun Wu, Qiong Yang, Hongchao Tang, Hongjun Yuan, Shan Fang
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-16 (2023)
Abstract Background Chemoresistance involves metastasis and aggressiveness of breast cancer (BC). Chemotherapy-elicited exosomes have been reported to be associated with drug resistance and pro-metastatic capacity of BC cells. Non-coding RNAs (ncRNAs
Externí odkaz:
https://doaj.org/article/cc4665b604a14cb6aa0e366b6a746883
Autor:
Lesang Shen, Huanhuan Huang, Zichen Wei, Wuzhen Chen, Jiaxin Li, Yao Yao, Jun Zhou, Jian Liu, Shanshan Sun, Wenjie Xia, Ting Zhang, Xiuyan Yu, Jun Shen, Weilan Wang, Jingxin Jiang, Jian Huang, Ming Jiang, Chao Ni
Publikováno v:
MedComm, Vol 4, Iss 6, Pp n/a-n/a (2023)
Abstract Small extracellular vesicles (sEVs) are essential mediators of intercellular communication within the tumor microenvironment (TME). Although the biological features of sEVs have been characterized based on in vitro culture models, recent evi
Externí odkaz:
https://doaj.org/article/df00ac3e0a1d49dfbb603eb7c05d337a
Autor:
Lesang Shen, Jun Zhou, Yiding Chen, Jinhua Ding, Haiyan Wei, Jian Liu, Wenjie Xia, Bojian Xie, Xiaohong Xie, Xujun Li, Yuechu Dai, Guobing Zhang, Xia Qiu, Chao Li, Shanshan Sun, Wuzhen Chen, Dihe Gong, Hengyu Li, Jian Huang, Xia Jiang, Chao Ni
Publikováno v:
Cancer Medicine, Vol 11, Iss 22, Pp 4157-4168 (2022)
Abstract Background Palbociclib was the only available cyclin‐dependent kinase 4/6 inhibitor in China until very recently, and its effect has not been systemically evaluated among Chinese patients. This study aims to assess the efficacy, safety and
Externí odkaz:
https://doaj.org/article/27faaebab4924b45b61f73902142f23a
Autor:
Lesang Shen, Huanhuan Huang, Jiaxin Li, Wuzhen Chen, Yao Yao, Jianming Hu, Jun Zhou, Fengbo Huang, Chao Ni
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionLipid metabolic reprogramming is gaining attention as a hallmark of cancers. Recent mounting evidence indicates that the malignant behavior of breast cancer (BC) is closely related to lipid metabolism. Here, we focus on the estrogen recep
Externí odkaz:
https://doaj.org/article/7f9571fcaad64072bf6d5e32f6d186c0
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Breast cancer is one of the most common tumors in women. Despite various treatments, the survival of patients with advanced breast cancer is still disappointing. Furthermore, finding an effective individualized treatment for different kinds of patien
Externí odkaz:
https://doaj.org/article/794857b3d3f44c58913156be9ff3124d
Autor:
Xuan Shao, Xiaoyan Jin, Zhigang Chen, Zhigang Zhang, Wuzhen Chen, Jingxin Jiang, Zhen Wang, Ying Cui, Wan-Hung Fan, Ke Wang, Xiuyan Yu, Jian Huang
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundCirculating tumor cells (CTCs) have been recognized as a sensitive biomarker for breast cancer (BC). This study aimed to comprehensively compare CTC with imaging modalities, including ultrasonography, mammography, and contrast-enhanced magn
Externí odkaz:
https://doaj.org/article/1325bedfd5ba4f0683a6449fb0582906
Autor:
Wuzhen Chen, Lesang Shen, Jingxin Jiang, Leyi Zhang, Zhigang Zhang, Jun Pan, Chao Ni, Zhigang Chen
Publikováno v:
Biomarker Research, Vol 9, Iss 1, Pp 1-16 (2021)
Abstract Tumor angiogenesis induces local hypoxia and recruits immunosuppressive cells, whereas hypoxia subsequently promotes tumor angiogenesis. Immunotherapy efficacy depends on the accumulation and activity of tumor-infiltrating immune cells (TIIC
Externí odkaz:
https://doaj.org/article/c32e8663b7ca49e58915dc69f6c1cd2d
Autor:
Leyi Zhang, Jun Pan, Zhen Wang, Chenghui Yang, Wuzhen Chen, Jingxin Jiang, Zhiyuan Zheng, Fang Jia, Yi Zhang, Jiahuan Jiang, Ke Su, Guohong Ren, Jian Huang
Publikováno v:
Frontiers in Oncology, Vol 11 (2022)
Breast cancer lung metastasis has a high mortality rate and lacks effective treatments, for the factors that determine breast cancer lung metastasis are not yet well understood. In this study, data from 1067 primary tumors in four public datasets rev
Externí odkaz:
https://doaj.org/article/5715fb6efd8a441e9e8e56c6817b843f