Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Wuyu Mao"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract The prodrug design strategy offers a potent solution for improving therapeutic index and expanding drug targets. However, current prodrug activation designs are mainly responsive to endogenous stimuli, resulting in unintended drug release an
Externí odkaz:
https://doaj.org/article/fb70002ec1f14987af8e9beb313e3b39
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/d681f59eb7e04c5aa95b00b3dd38a44b
Autor:
Yunzhou Dong, Changyu Ren, Mengli Zhu, Dan Zhang, Ting Wang, Jifa Zhang, Jiaxing Wang, Wuyu Mao, Fangyi Long
Publikováno v:
Future Medicinal Chemistry. 14:1923-1941
The FGF receptors (FGFRs) belong to a family of receptor tyrosine kinases. Abundant evidence shows that FGFRs are closely related to tumor cell invasion and angiogenesis. Hence, targeted modulation of FGFRs has become an effective strategy for cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d39478a29fb395932420fa1555ce4c6
https://doi.org/10.4155/fmc-2022-0194
https://doi.org/10.4155/fmc-2022-0194
Publikováno v:
Organic Letters. 24:5293-5297
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bd64d2c1a4ef3745f1f29509df6b6ee
https://doi.org/10.1021/acs.orglett.2c01873
https://doi.org/10.1021/acs.orglett.2c01873
Publikováno v:
Chemical Communications. 58:4020-4023
A smart lipid droplet specific fluorescent probe (LDs-DM) with dual-emission in water (706 nm) and oil (535 nm) under single-excitation was prepared for revealing the ultra-structure of the aqueous and lipidic microenvironment in living cells, fatty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43d79bda244d7fef6d15958b283f71b3
https://doi.org/10.1039/d2cc00795a
https://doi.org/10.1039/d2cc00795a
Autor:
Jiarui Hu, Dan Zhang, Keyue Tian, Changyu Ren, Heng Li, Congcong Lin, Xiaoli Huang, Jie Liu, Wuyu Mao, Jifa Zhang
Publikováno v:
European Journal of Medicinal Chemistry. 256:115475
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1dfcd65d7f6739b91acf7085c0e7f3a5
https://doi.org/10.1016/j.ejmech.2023.115475
https://doi.org/10.1016/j.ejmech.2023.115475
Publikováno v:
Angewandte Chemie. 134
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9907f43d0a2b2a2ee453683a7265e38
https://doi.org/10.1002/ange.202282261
https://doi.org/10.1002/ange.202282261
Publikováno v:
Angewandte Chemie International Edition. 61
Bioorthogonal fluorogenic dyes are indispensable tools in wash-free bioimaging of specific biological targets. However, the fluorogenicity of existing tetrazine-based bioorthogonal probes deteriorates as the emission wavelength shifts towards the NIR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2027887d9bff6fde466903214f6a0710
https://doi.org/10.1002/anie.202117386
https://doi.org/10.1002/anie.202117386
Publikováno v:
ACS chemical neuroscience. 13(5)
Alzheimer's disease (AD) is a high mortality and high disability rates neurodegenerative disease characterized by irreversible progression and poses a significant social and economic burden throughout the world. However, currently approved AD therape
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53798a8f26ee3eb8afa00546ff7d992b
https://pubmed.ncbi.nlm.nih.gov/35132849
https://pubmed.ncbi.nlm.nih.gov/35132849
Autor:
Xin Xin, Yue Wang, Lele Zhang, Dan Zhang, Leihao Sha, Ziyu Zhu, Xiaoyi Huang, Wuyu Mao, Jifa Zhang
Publikováno v:
European Journal of Medicinal Chemistry. 248:115102
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::989a420d8fe32091c448abd77cc7b0d1
https://doi.org/10.1016/j.ejmech.2023.115102
https://doi.org/10.1016/j.ejmech.2023.115102