Enhancer-Promoter Communication: It's Not Just About Contact

Autor: Wurmser, Annabelle, Basu, Srinjan

Cis-regulatory elements such as enhancers can be located even a million base pairs away from their cognate promoter and yet modulate gene transcription. Indeed, the 3D organisation of chromatin enables the establishment of long-range enhancer-promote

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Enhancer-Promoter Communication: It's Not Just About Contact.

Autor: Wurmser A; Wellcome-MRC Cambridge Stem Cell Institute, Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom., Basu S; Wellcome-MRC Cambridge Stem Cell Institute, Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom.; Department of Physiology, Development, and Neuroscience, University of Cambridge, Cambridge, United Kingdom.

Publikováno v: Frontiers in molecular biosciences [Front Mol Biosci] 2022 Apr 19; Vol. 9, pp. 867303. Date of Electronic Publication: 2022 Apr 19 (Print Publication: 2022).