Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Wuling Zhu"'
Autor:
Lingtong Zhi, Xing Wang, Qing Gao, Wenhui He, Chongye Shang, Changjiang Guo, Zhiyuan Niu, Wuling Zhu, Xuan Zhang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 165, Iss , Pp 115136- (2023)
Natural killer (NK) cells are derived from hematopoietic stem cells. They belong to the innate lymphoid cell family, which is an important part of innate immunity. This family plays a role in the body mainly through the release of perforin, granzyme,
Externí odkaz:
https://doaj.org/article/f598c9a91c014d4daa310598b42ed818
Publikováno v:
Cell Transplantation, Vol 31 (2022)
Use of chimeric antigen receptors (CARs), as an immune cell therapy, has generated excellent clinical outcomes against hematologic tumors in recent years. Among them, the CAR-NK (natural killer) therapy has shown better efficacy, and less toxicity, t
Externí odkaz:
https://doaj.org/article/5a2b8d70ab294fa1b1ea10cb57097d5e
Autor:
Zhiyuan Niu, Zhixia Luo, Pengyang Sun, Linwei Ning, Xinru Jin, Guanxu Chen, Changjiang Guo, Lingtong Zhi, Wei Chang, Wuling Zhu
Publikováno v:
BioDesign Research, Vol 2022 (2022)
Camelid single-domain antibody fragments (nanobodies) are an emerging force in therapeutic biopharmaceuticals and clinical diagnostic reagents in recent years. Nearly all nanobodies available to date have been obtained by animal immunization, a bottl
Externí odkaz:
https://doaj.org/article/e8393658e30e4a15ac94a11f7b9489f3
Publikováno v:
Turkish Journal of Biochemistry. 45:817-823
Objectives synNotch receptors can get different inputs about the outside environment into cells; however, synNotch system doesn’t work for soluble ligands. This study aims to explore the activation efficiency of different ligand carriers on synNotc
Autor:
Zhiyuan Niu, Wenjiao Xia, Changjiang Guo, Lingtong Zhi, Chen Liang, Wang Xiaoyin, Wuling Zhu, Huiyong Zhang
Publikováno v:
Molecular Immunology. 122:132-140
A great deal of evidence has shown that anti-angiogenic molecules and antibodies targeting the VEGF-A/VEGFRs signal pathway can also reverse tumor-induced immunosuppression to an extent. VEGF165b, an anti-angiogenic VEGF-A isoform, has demonstrated c
Autor:
Huiyong Zhang, Lingtong Zhi, Changjiang Guo, Li Mingfeng, Wuling Zhu, Meichen Yin, Chengui Lu
Publikováno v:
Biochemical and Biophysical Research Communications. 523:745-752
Cell-based immunotherapy continues to be a promising avenue for cancers that standard therapy has failed. Although the specificity, avidity, and efficacy of infused cells have improved, immunocytotherapy still faces substantial hurdles. To this end,
Autor:
Yuyang Zhang, Changjiang Guo, Yan Wang, Ming Lin, Cui Caixia, Yao Zhang, Wuling Zhu, Yuanchen Dai, Tingwei Liu, Chenyan Zhou
Publikováno v:
International Journal of Systematic and Evolutionary Microbiology. 70:334-339
A novel Gram-stain-negative, rod-shaped, non-spore-forming, non-flagellated, strictly aerobic strain, designated A6024T, was isolated from coastal seawater near Rizhao, PR China (119.61° E 35.47° N). The organism grew optimally at 28 °C, in pH 6.0
Autor:
Yan Wang, Lixin Zhou, Wuling Zhu, Chunyu Meng, Yao Zhang, Chenyan Zhou, Xuan Zhang, Changqin Jing, Tingwei Liu
Publikováno v:
International Journal of Systematic and Evolutionary Microbiology. 69:3857-3862
A novel bacterial strain, C3212T, was isolated from a marine alga collected from the sea shore of Yantai, China. The strain was Gram-stain-negative, rod-shaped, aerobic, non-motile, and oxidase- and catalase-positive. Growth was observed at 8–37 °
Autor:
Lingtong Zhi, Meichen Yin, Xin Su, Zikang Zhang, Hui Lu, Mingfeng Li, Changjiang Guo, Zhiyuan Niu, Xuan Zhang, Wuling Zhu
Publikováno v:
Biochemical and biophysical research communications. 600
Engineered natural killer (NK) cell-based therapies have been potentially broadly applicable and exhibited promising results in clinical trials, particularly in the fight against cancers. NK cell immunotherapy however always remains variable. One maj
Autor:
Wuling Zhu, Xiali Guo, Lingtong Zhi, Jie Yu, Han Chen, Tong Wang, Zhiyuan Niu, Xiaojuan Li, Changjiang Guo, Hui Lu
Adoptive chimeric antigen receptor (CAR)-modified T or NK cells (CAR-T/NK) have emerged as a novel form of disease treatment. Lentiviral vectors (LVs) are commonly employed to engineer T/NK cells for the efficient expression of CARs. This study repor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34574ee4e1ad64d9e3355cb3a4b7cb0d
https://doi.org/10.1101/2021.07.11.451925
https://doi.org/10.1101/2021.07.11.451925