Practical survival analysis tools for heterogeneous cohorts and informative censoring

Autor: Rowley, M., Garmo, H., Van Hemelrijck, M., Wulaningsih, W., Grundmark, B., Zethelius, B., Hammar, N., Walldius, G., Inoue, M., Holmberg, L., Coolen, A. C. C.

In heterogeneous cohorts and those where censoring by non-primary risks is informative many conventional survival analysis methods are not applicable; the proportional hazards assumption is usually violated at population level and the observed crude

Externí odkaz: http://arxiv.org/abs/1511.06849

Environment-wide association study to comprehensively test and validate associations between nutrition and lifestyle factors and testosterone deficiency: NHANES 1988–1994 and 1999–2004

Autor: Lopez, D. S., Wulaningsih, W., Tsilidis, K. K., Baillargeon, J., Williams, S. B., Urban, R., Rohrmann, S.

Publikováno v: Hormones; 20240101, Issue: Preprints p1-10, 10p

ALIX Regulates Tumor-Mediated Immunosuppression by Controlling EGFR Activity and PD-L1 Presentation

Autor: Monypenny, J, Milewicz, H, Flores-Borja, F, Weitsman, G, Cheung, A, Chowdhury, R, Burgoyne, T, Arulappu, A, Lawler, K, Barber, P, Vicencio, J, Keppler, M, Wulaningsih, W, Davidson, S, Fraternali, F, Woodman, N, Turmaine, M, Gillett, C, Franz, D, Quezada, S, Futter, C, Von Kriegsheim, A, Kolch, W, Vojnovic, B, Carlton, J, Ng, T

Publikováno v: Monypenny, J, Milewicz, H, Flores-Borja, F, Weitsman, G, Cheung, A, Chowdhury, R, Burgoyne, T, Arulappu, A, Lawler, K, Barber, P R, Vicencio, J M, Keppler, M, Wulaningsih, W, Davidson, S M, Fraternali, F, Woodman, N, Turmaine, M, Gillett, C, Franz, D, Quezada, S A, Futter, C E, Von Kriegsheim, A, Kolch, W, Vojnovic, B, Carlton, J G & Ng, T 2018, ' ALIX Regulates Tumor-Mediated Immunosuppression by Controlling EGFR Activity and PD-L1 Presentation ', Cell Reports, vol. 24, no. 3, pp. 630-641 . https://doi.org/10.1016/j.celrep.2018.06.066
Cell Reports
Monypenny, J, Milewicz, H, Flores-borja, F, Weitsman, G, Cheung, A, Chowdhury, R, Burgoyne, T, Arulappu, A, Lawler, K, Barber, P R, Vicencio, J M, Keppler, M, Wulaningsih, W, Davidson, S M, Fraternali, F, Woodman, N, Turmaine, M, Gillett, C, Franz, D, Quezada, S A, Futter, C E, Von Kriegsheim, A, Kolch, W, Vojnovic, B, Carlton, J G & Ng, T 2018, ' ALIX Regulates Tumor-Mediated Immunosuppression by Controlling EGFR Activity and PD-L1 Presentation ', Cell Reports, vol. 24, no. 3, pp. 630-641 . https://doi.org/10.1016/j.celrep.2018.06.066
Cell Reports, Vol 24, Iss 3, Pp 630-641 (2018)

Summary The immunosuppressive transmembrane protein PD-L1 was shown to traffic via the multivesicular body (MVB) and to be released on exosomes. A high-content siRNA screen identified the endosomal sorting complexes required for transport (ESCRT)-ass

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::1255f554a189a5104068ccf8a8bca296
https://kclpure.kcl.ac.uk/en/publications/3d1e5840-7de2-4960-96ab-d5ca85a316a5

Association of serum inorganic phosphate with sex steroid hormones and vitamin D in a nationally representative sample of men.

Autor: Wulaningsih, W.¹, Van Hemelrijck, M.¹, Michaelsson, K.², Kanarek, N.^3,4, Nelson, W. G.^4,5,6, Ix, J. H.⁷, Platz, E. A.^4,5,8, Rohrmann, S.⁹

Publikováno v: Andrology. Nov2014, Vol. 2 Issue 6, p967-976. 10p.

Detecting intratumoral heterogeneity of EGFR activity by liposome-based in vivo transfection of a fluorescent biosensor

Autor: Weitsman, G, Mitchell, NJ, Evans, R, Cheung, A, Kalber, TL, Bofinger, R, Fruhwirth, GO, Keppler, M, Wright, ZVF, Barber, PR, Gordon, P, de Koning, T, Wulaningsih, W, Sander, K, Vojnovic, B, Ameer-Beg, S, Lythgoe, M, Arnold, JN, Årstad, E, Festy, F, Hailes, HC, Tabor, AB, Ng, T

Publikováno v: Oncogene
Weitsman, G, Mitchell, N J, Evans, R, Cheung, A, Kalber, T L, Bofinger, R, Fruhwirth, G O, Keppler, M, Wright, Z V F, Barber, P R, Gordon, P, de Koning, T, Wulaningsih, W, Sander, K, Vojnovic, B, Ameer-Beg, S, Lythgoe, M, Arnold, J N, Årstad, E, Festy, F, Hailes, H C, Tabor, A B & Ng, T 2017, ' Detecting intratumoral heterogeneity of EGFR activity by liposome-based in vivo transfection of a fluorescent biosensor ', Oncogene, vol. 36, no. 25, pp. 3618–3628 . https://doi.org/10.1038/onc.2016.522

Despite decades of research in the epidermal growth factor receptor (EGFR) signalling field, and many targeted anti-cancer drugs that have been tested clinically, the success rate for these agents in the clinic is low, particularly in terms of the im

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::858fc396aef7cd23f52cb66d129a5f5a
http://ora.ox.ac.uk/objects/uuid: