Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Wuhu Zhang"'
Autor:
Heli Gao, Wuhu Zhang, Zheng Li, Wensheng Liu, Mengqi Liu, Qifeng Zhuo, Yihua Shi, Wenyan Xu, Chenjie Zhou, Yi Qin, Jin Xu, Jie Chen, Xianjun Yu, Xiaowu Xu, Shunrong Ji
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Ki67 index changes during the treatment of metastatic pancreatic neuroendocrine tumor (PanNET) treatment. The study aimed to detect alterations of grade based on Ki67 index and immune microenvironment in PanNET responding to capec
Externí odkaz:
https://doaj.org/article/07be9ba86f7a4a8dbe7f208d56ee4cc4
Autor:
Junfeng Xu, Xin Lou, Fei Wang, Wuhu Zhang, Xiaowu Xu, Zeng Ye, Qifeng Zhuo, Yan Wang, Desheng Jing, Guixiong Fan, Xuemin Chen, Yue Zhang, Chenjie Zhou, Jie Chen, Yi Qin, Xianjun Yu, Shunrong Ji
Publikováno v:
Advanced Science, Vol 11, Iss 35, Pp n/a-n/a (2024)
Abstract O6‐methylguanine DNA methyltransferase (MGMT) removes alkyl adducts from the guanine O6 position (O6‐MG) and repairs DNA damage. High MGMT expression results in poor response to temozolomide (TMZ). However, the biological importance of M
Externí odkaz:
https://doaj.org/article/b9de0dc9db3b4166a7eac67e8116e9ed
Autor:
Junfeng Xu, Wuhu Zhang, Xin Lou, Zeng Ye, Yi Qin, Jie Chen, Xiaowu Xu, Xianjun Yu, Shunrong Ji
Publikováno v:
Cancer Biology & Medicine, Vol 20, Iss 10, Pp 721-727 (2023)
Externí odkaz:
https://doaj.org/article/e80832419cbc4f1896261ce43b11b17d
Autor:
Longyun Ye, Kaizhou Jin, Zhenyu Liao, Zhiwen Xiao, Huaxiang Xu, Xuan Lin, Hao Li, Tianjiao Li, Wuhu Zhang, Xuan Han, Wenquan Wang, Heli Gao, Liang Liu, Weiding Wu, Xianjun Yu
Publikováno v:
EBioMedicine, Vol 79, Iss , Pp 104016- (2022)
Summary: Background: Previously, we uncovered a patient subgroup with highly malignant pancreatic cancer with serum markers CEA+/CA125+/CA19-9 ≥ 1000 U/mL (triple-positive, TP). However, the underlying immunosuppressive mechanism in the tumor immun
Externí odkaz:
https://doaj.org/article/5ac80511a6ba49eda212ca5b9c13eb6d
Autor:
Xin Lou, Heli Gao, Xiaowu Xu, Zeng Ye, Wuhu Zhang, Fei Wang, Jie Chen, Yue Zhang, Xuemin Chen, Yi Qin, Xianjun Yu, Shunrong Ji
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundThe four major pathways in gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) including chromatin remodeling, DNA damage repair, activation of mTOR signaling, and telomere maintenance were mediated by some critical molecules and con
Externí odkaz:
https://doaj.org/article/6cf291b2889d40289fe152c65bb81a35
Autor:
Tianjiao Li, Hao Li, Shuo Li, Shuaishuai Xu, Wuhu Zhang, Heli Gao, Huaxiang Xu, Chuntao Wu, Wenquan Wang, Xianjun Yu, Liang Liu
Publikováno v:
Cancer Medicine, Vol 8, Iss 11, Pp 5223-5231 (2019)
Abstract Pancreatic ductal adenocarcinoma (PDAC) is a highly malignant cancer with limited treatment options. Chimeric antigen receptor T cells (CAR‐T) are genetically engineered T cells that can specifically kill tumor cells without major histocom
Externí odkaz:
https://doaj.org/article/5e5bfb350c044657b35780854f425ae4
Autor:
Shuaishuai Xu, Huaxiang Xu, Wenquan Wang, Shuo Li, Hao Li, Tianjiao Li, Wuhu Zhang, Xianjun Yu, Liang Liu
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-22 (2019)
Abstract Collagen is the major component of the tumor microenvironment and participates in cancer fibrosis. Collagen biosynthesis can be regulated by cancer cells through mutated genes, transcription factors, signaling pathways and receptors; further
Externí odkaz:
https://doaj.org/article/b8b51f6937ce41229bd395a7985054b6
Autor:
Shuo Li, Huaxiang Xu, Chuntao Wu, Wenquan Wang, Wei Jin, Heli Gao, Hao Li, Shirong Zhang, Jinzhi Xu, Wuhu Zhang, Shuaishuai Xu, Tianjiao Li, Quanxing Ni, Xianjun Yu, Liang Liu
Publikováno v:
Cancer Medicine, Vol 8, Iss 2, Pp 572-584 (2019)
Abstract Pancreatic ductal adenocarcinoma (PDAC) is a devastating malignancy with poor prognosis. Many preoperative biomarkers can predict postoperative survival of PDAC patients. In this study, we created a novel ratio index based on preoperative li
Externí odkaz:
https://doaj.org/article/03a492ba76094db193be227f3f7e4ae9
Publikováno v:
Shock and Vibration, Vol 2015 (2015)
The total weight of Extended-Range Electric Vehicle (E-REV) is too heavy, which affects rear-end collision safety. Using numerical simulation, a lightweight method is designed to reduce E-REV body and key parts weight based on rear-end collision fail
Externí odkaz:
https://doaj.org/article/22b4d085b2db4dbda9e8abe5fa884b23
Autor:
Yan Wang, Fei Wang, Yi Qin, Xin Lou, Zeng Ye, Wuhu Zhang, Heli Gao, Jie Chen, Xiaowu Xu, Xianjun Yu, Shunrong Ji
Publikováno v:
Endocrine. 80:266-282
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::630917ff5bcc97700e65202f2ec492b4
https://doi.org/10.1007/s12020-023-03299-6
https://doi.org/10.1007/s12020-023-03299-6