Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Wuhbet, Abraham"'
Autor:
Nicholas L. Truex, Somesh Mohapatra, Mariane Melo, Jacob Rodriguez, Na Li, Wuhbet Abraham, Deborah Sementa, Faycal Touti, Derin B. Keskin, Catherine J. Wu, Darrell J. Irvine, Rafael Gómez-Bombarelli, Bradley L. Pentelute
Publikováno v:
ACS Central Science, Vol 10, Iss 4, Pp 793-802 (2024)
Externí odkaz:
https://doaj.org/article/99dad73fc208488c99c976dab55c812a
Autor:
Kristen A. Rodrigues, Christopher A. Cottrell, Jon M. Steichen, Bettina Groschel, Wuhbet Abraham, Heikyung Suh, Yash Agarwal, Kaiyuan Ni, Jason Y. H. Chang, Parisa Yousefpour, Mariane B. Melo, William R. Schief, Darrell J. Irvine
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-14 (2023)
Abstract In the ongoing effort to develop a vaccine against HIV, vaccine approaches that promote strong germinal center (GC) responses may be critical to enable the selection and affinity maturation of rare B cell clones capable of evolving to produc
Externí odkaz:
https://doaj.org/article/41280b26b64f4887a8b93d75737a93e1
Autor:
Byungji, Kim, Ryan R, Hosn, Tanaka, Remba, Dongsoo, Yun, Na, Li, Wuhbet, Abraham, Mariane B, Melo, Manuel, Cortes, Bridget, Li, Yuebao, Zhang, Yizhou, Dong, Darrell J, Irvine
Publikováno v:
Journal of Controlled Release. 353:241-253
The recent clinical success of multiple mRNA-based SARS-CoV-2 vaccines has proven the potential of RNA formulated in lipid nanoparticles (LNPs) in humans, and products based on base-modified RNA, sequence-optimized RNA, and self-replicating RNAs form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00a27996f51128028b14f168abfe074d
https://doi.org/10.1016/j.jconrel.2022.11.022
https://doi.org/10.1016/j.jconrel.2022.11.022
Autor:
Darrell J. Irvine, Bradley L. Pentelute, Sylvie Le Gall, Na Li, Angela Q. Zhang, Mariane B. Melo, Wuhbet Abraham, Simon Liang, Jens Dinter, Mark R. Karver, Chensu Wang, Naveen K. Mehta, Rebecca L. Holden, Kelly D. Moynihan
Captions for Supplementary Figures and Supplementary Table
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00c0dc4fe26ab57c9073c671506e52ae
https://doi.org/10.1158/2326-6066.22539502.v1
https://doi.org/10.1158/2326-6066.22539502.v1
Autor:
Darrell J. Irvine, Bradley L. Pentelute, Sylvie Le Gall, Na Li, Angela Q. Zhang, Mariane B. Melo, Wuhbet Abraham, Simon Liang, Jens Dinter, Mark R. Karver, Chensu Wang, Naveen K. Mehta, Rebecca L. Holden, Kelly D. Moynihan
Antitumor T-cell responses have the potential to be curative in cancer patients, but the induction of potent T-cell immunity through vaccination remains a largely unmet goal of immunotherapy. We previously reported that the immunogenicity of peptide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a24c2c28b210d6696428cca7382d88b
https://doi.org/10.1158/2326-6066.c.6549109.v1
https://doi.org/10.1158/2326-6066.c.6549109.v1
Autor:
Darrell J. Irvine, Bradley L. Pentelute, Sylvie Le Gall, Na Li, Angela Q. Zhang, Mariane B. Melo, Wuhbet Abraham, Simon Liang, Jens Dinter, Mark R. Karver, Chensu Wang, Naveen K. Mehta, Rebecca L. Holden, Kelly D. Moynihan
Supplementary Figure S3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2952f288620e8aa62f4af0ffc5817cef
https://doi.org/10.1158/2326-6066.22539511.v1
https://doi.org/10.1158/2326-6066.22539511.v1
Autor:
Darrell J. Irvine, Bradley L. Pentelute, Sylvie Le Gall, Na Li, Angela Q. Zhang, Mariane B. Melo, Wuhbet Abraham, Simon Liang, Jens Dinter, Mark R. Karver, Chensu Wang, Naveen K. Mehta, Rebecca L. Holden, Kelly D. Moynihan
Supplementary Table S1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::042eba1623b530573ffe68f47b7e0439
https://doi.org/10.1158/2326-6066.22539499
https://doi.org/10.1158/2326-6066.22539499
Autor:
Aereas Aung, Ang Cui, Laura Maiorino, Ava P. Amini, Justin R. Gregory, Maurice Bukenya, Yiming Zhang, Heya Lee, Christopher A. Cottrell, Duncan M. Morgan, Murillo Silva, Heikyung Suh, Jesse D. Kirkpatrick, Parastoo Amlashi, Tanaka Remba, Leah M. Froehle, Shuhao Xiao, Wuhbet Abraham, Josetta Adams, J. Christopher Love, Phillip Huyett, Douglas S. Kwon, Nir Hacohen, William R. Schief, Sangeeta N. Bhatia, Darrell J. Irvine
Publikováno v:
Science
The structural integrity of vaccine antigens is critical to the generation of protective antibody responses, but the impact of protease activity on vaccination in vivo is poorly understood. We characterized protease activity in lymph nodes and found
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c651a6c41babaa4eff4f551a3120dc0e
https://doi.org/10.1126/science.abn8934
https://doi.org/10.1126/science.abn8934
Autor:
Leyuan Ma, Duncan M. Morgan, Ina Sulkaj, Parisa Yousefpour, Charles A. Whittaker, Wuhbet Abraham, Na Li, J. Christopher Love, Darrell J. Irvine
Chimeric Antigen Receptor (CAR) T-cell therapy can be effective in treating human cancer but loss of the antigen recognized by the CAR poses a major obstacle. Here, we report an approach for vaccine boosting CAR T-cells, which triggers engagement of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbb058a8f4ae2d3ca55ffac5e154b663
https://doi.org/10.1101/2022.10.05.511036
https://doi.org/10.1101/2022.10.05.511036
A particulate saponin/TLR agonist vaccine adjuvant alters lymph flow and modulates adaptive immunity
Autor:
Wuhbet Abraham, Erik Georgeson, Kangsan Roh, Jason Y. Chang, Shuhao Xiao, Daniel Lingwood, Brittany L. Hartwell, Ivy Phung, Bettina Groschel, Diane G Carnathan, Ayush Thomas, Kimberly M. Cirelli, Darrell J. Irvine, Murillo Silva, Li Zhongming, Galit Alter, Guido Silvestri, Jan Willem Maurits van Wijnbergen, Jinal Bhiman, Caitlyn Linde, Yu Kato, Timothy P. Padera, Raiza Bastidas, Hannah C. Watkins, William R. Schief, Sonya Haupt, Swati Kataria, Julia Bals, Dennis R. Burton, Ruth M. Ruprecht, Shane Crotty, Nicole Phelps, Kristen A Rodrigues, Mariane B. Melo, Angela M. Belcher, Brian L. Freeman, Na Li, Benjamin J. Cossette, Aereas Aung, Nathaniel I. Bloom, Chiamaka A. Enemuo
Publikováno v:
Sci Immunol
Saponins are potent and safe vaccine adjuvants, but their mechanisms of action remain incompletely understood. Here, we explored the properties of several saponin formulations, including immunostimulatory complexes (ISCOMs) formed by the self-assembl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a97d19fd8aafb20e222dae6d4f635287
https://doi.org/10.1126/sciimmunol.abf1152
https://doi.org/10.1126/sciimmunol.abf1152