Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Wuhao Li"'
Publikováno v:
Neurobiology of Disease, Vol 198, Iss , Pp 106561- (2024)
Neuroinflammation and mitochondrial dysfunction are closely intertwined with the pathophysiology of neurological disorders. Recent studies have elucidated profound alterations in mitochondrial dynamics across a spectrum of neurological disorders. Dyn
Externí odkaz:
https://doaj.org/article/6c3f80cae9654894b310f335745acdb2
Autor:
Wuhao Li, Peiyang Cai, Ye Xu, Weihong Tian, Licong Jing, Qiaoyi Lv, Yangjing Zhao, Hui Wang, Qixiang Shao
Publikováno v:
Journal of Immunology Research, Vol 2024 (2024)
B cells are essential for humoral immune response due to their ability to secrete antibodies. The development of B cells from the bone marrow to the periphery is tightly regulated by a complex set of immune signals, and each subset of B cells has a u
Externí odkaz:
https://doaj.org/article/47e6e97ddc5d49439aa5c725cfbea342
Autor:
Minmin Fan, Jian Gao, Lin Zhou, Wenwen Xue, Yixuan Wang, Jingwei Chen, Wuhao Li, Ying Yu, Bo Liu, Yan Shen, Qiang Xu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 12, Pp 4407-4423 (2022)
Chemoresistance remains a major obstacle to successful treatment of triple negative breast cancer (TNBC). Identification of druggable vulnerabilities is an important aim for TNBC therapy. Here, we report that SERCA2 expression correlates with TNBC pr
Externí odkaz:
https://doaj.org/article/4dd2a3ad63684f25be38bb417775888e
Autor:
Weihong Tian, Gaofeng Qin, Miaomiao Jia, Wuhao Li, Weili Cai, Hui Wang, Yangjing Zhao, Xuanwen Bao, Wangzhi Wei, Yu Zhang, Qixiang Shao
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The fundamental principle of immune checkpoint blockade (ICB) is to protect tumor-infiltrating T cells from being exhausted. Despite the remarkable success achieved by ICB treatment, only a small group of patients benefit from it. Characterized by a
Externí odkaz:
https://doaj.org/article/f909246f51304df39f2d11c8e8c38f7c
Autor:
Wenwen Xue, Xin Li, Wuhao Li, Yixuan Wang, Chengfei Jiang, Lin Zhou, Jian Gao, Ying Yu, Yan Shen, Qiang Xu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-12 (2022)
Abstract Loss-of-function mutations frequently occur in tumor suppressor genes, i.e., p53, during the malignant progression of various cancers. Whether any intrinsic suppressor carries a rare mutation is largely unknown. Here, we demonstrate that int
Externí odkaz:
https://doaj.org/article/ccc62ef18abb43dfa1bce9f13ebff2d9
Publikováno v:
Frontiers in Plant Science, Vol 13 (2022)
It is extremely necessary to achieve the rapid harvesting of table grapes planted with a standard trellis in the grape industry. The design and experimental analysis of a dual-arm high-speed grape-harvesting robot were carried out to address the limi
Externí odkaz:
https://doaj.org/article/fd59874764eb411f92a11d94c30e75f1
Autor:
Wenwen Xue, Wuhao Li, Ying Yu, Bo Zhang, Yixue Wang, Lin Zhou, Zhixiu Chen, Liwei Wang, Huiming Ge, Qiang Xu, Yan Shen
Publikováno v:
Journal of Pharmacy and Pharmacology. 75:523-532
Objectives Enrichment for therapy-resistant cancer stem cells hampers the treatment of triple-negative breast cancer. Targeting these cells via suppression of Notch signalling can be a potential therapeutic strategy. This study aimed to uncover the m
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-11 (2024)
Abstract Background Currently, the prevalence of obesity is on the rise annually. Bariatric surgery stands out as the most efficacious approach for addressing obesity. Obese patients are more prone to experience moderate to severe pain after surgery
Externí odkaz:
https://doaj.org/article/96b9d879f94146eebde3c7ce7c0a7bea
Publikováno v:
Journal of International Medical Research, Vol 52 (2024)
Here, the case of a female patient in her late 60s, who presented to hospital for a scheduled health check relating to a history of myelofibrosis for the previous 9 years, is described. She recently experienced weight loss and abdominal distention. P
Externí odkaz:
https://doaj.org/article/473ab54b372c4ff9b33129c0d39bf081
Autor:
Lin Zhou, Wenwen Xue, Cheng-Fei Jiang, Qiang Xu, Xue-Feng Wu, Minmin Fan, Yang Sun, Wuhao Li, Xin Li, Jingwei Chen, Yan Shen, Hui Ming Ge, Jian Gao, Xudong Wu, Yixuan Wang
Publikováno v:
Cell Death and Disease, Vol 11, Iss 8, Pp 1-13 (2020)
Cell Death & Disease
Cell Death & Disease
Breast cancer is a heterogeneous disease that includes different molecular subtypes. The basal-like subtype has a poor prognosis and a high recurrence rate, whereas the luminal-like subtype confers a more favorable patient prognosis partially due to