Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Wuding Zhou"'
Autor:
Jia-Xing Wang, Bo Cao, Ning Ma, Kun-Yi Wu, Wan-Bing Chen, Weiju Wu, Xia Dong, Cheng-Fei Liu, Ya-Feng Gao, Teng-Yue Diao, Xiao-Yun Min, Qing Yong, Zong-Fang Li, Wuding Zhou, Ke Li
Publikováno v:
JCI Insight, Vol 8, Iss 5 (2023)
Collectin-11 (CL-11) is a recently described soluble C-type lectin that has distinct roles in embryonic development, host defence, autoimmunity, and fibrosis. Here we report that CL-11 also plays an important role in cancer cell proliferation and tum
Externí odkaz:
https://doaj.org/article/769f996492494428886559efc2bfb3ba
Autor:
Kun-Yi Wu, Bo Cao, Chun-Xuan Wang, Xue-Ling Yang, Shu-Juan Zhao, Teng-Yue Diao, Li-Rong Lin, Guo-Xiu Zhao, Wuding Zhou, Ju-Rong Yang, Ke Li
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Our previous work using a murine model of pyelonephritis demonstrated that the C5a/C5aR1 axis plays a pathogenic role in acute kidney infection. In this study, we report that the C5a/C5aR1 axis also plays a pathogenic role in acute bladder infection.
Externí odkaz:
https://doaj.org/article/5d06ec5d72794771a762c253d28d0260
Autor:
Yun Song, Kun-Yi Wu, Weiju Wu, Zhao-Yang Duan, Ya-Feng Gao, Liang-Dong Zhang, Tie Chong, Malgorzata A. Garstka, Wuding Zhou, Ke Li
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Recent work in a murine model of ascending urinary tract infection has suggested that C5a/C5aR1 interactions play a pathogenic role in the development of renal infection through enhancement of bacterial adhesion/colonization to renal tubular epitheli
Externí odkaz:
https://doaj.org/article/b25d9368b9354b44b1f8d32ecc008d25
Autor:
Cheng-Fei Liu, Xiao-Yun Min, Naiyin Wang, Jia-Xing Wang, Ning Ma, Xia Dong, Bing Zhang, Weiju Wu, Zong-Fang Li, Wuding Zhou, Ke Li
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Complement receptor 3 (CR3) is expressed abundantly on natural killer (NK) cells; however, whether it plays roles in NK cell-dependent tumor surveillance is largely unknown. Here, we show that CR3 is an important negative regulator of NK cell functio
Externí odkaz:
https://doaj.org/article/599d07be48b04185936b69d782f833ca
Autor:
Shu‐Juan Zhao, Kun‐Yi Wu, Xiao‐Yun Min, Chun‐Xuan Wang, Bo Cao, Ning Ma, Xue‐Ling Yang, Zhuo‐Ran Zhu, Rong‐Guo Fu, Wuding Zhou, Ju‐Rong Yang, Ke Li
Publikováno v:
The FASEB Journal. 36
Emerging evidence suggest that C3aR plays important roles in homeostasis, host defense and disease. Although it is known that C3aR is protective in several models of acute bacterial infections, the role for C3aR in chronic infection is largely unknow
Autor:
Jia-Xing Wang, Shu-Juan Zhao, Ting Zhang, Guoxiu Zhao, Wuding Zhou, Na Wang, Ke Li, Ning Ma, Zongfang Li, Kun-Yi Wu
Publikováno v:
Kidney International. 96:612-627
Both the C3a/C3aR and C5a/C5aR1 axes are regarded as important pathways for inducing and regulating inflammatory responses. It is well documented that the C5a/C5aR1 axis is a potent inflammatory mediator in the pathogenesis of many clinic disorders.
Autor:
Ke Li, Jia-Xing Wang, Nirmal K. Banda, Ang Li, Na Wang, Teng-Yue Diao, Dan Liu, Ning Ma, Jia-Yu Liu, Zongfang Li, Conrad A. Farrar, Rafael Bayarri-Olmos, Cui Qiang, Wuding Zhou, Xiao Yang, Li Xue, Weiju Wu, Peter Garred, Baojun Zhang, Kun-Yi Wu
Publikováno v:
Wang, N, Wu, W, Qiang, C, Ma, N, Wu, K, Liu, D, Wang, J X, Yang, X, Xue, L, Diao, T Y, Liu, J Y, Li, A, Zhang, B, Li, Z F, Farrar, C A, Banda, N K, Bayarri-Olmos, R, Garred, P, Zhou, W & Li, K 2021, ' Protective Role of Collectin 11 in a Mouse Model of Rheumatoid Arthritis ', Arthritis and Rheumatology, vol. 73, no. 8, pp. 1430-1440 . https://doi.org/10.1002/art.41696
Arthritis Rheumatol
Wang, N, Wu, W, Qiang, C, Ma, N, Wu, K, Liu, D, Wang, J, Yang, X, Xue, L, Diao, T, Liu, J, Li, A, Zhang, B, Li, Z, Farrar, C A, Banda, N K, Bayarri-olmos, R, Garred, P, Zhou, W & Li, K 2021, ' Protective Role of Collectin 11 in a Mouse Model of Rheumatoid Arthritis ', Arthritis and Rheumatology, vol. 73, no. 8, pp. 1430-1440 . https://doi.org/10.1002/art.41696
Arthritis Rheumatol
Wang, N, Wu, W, Qiang, C, Ma, N, Wu, K, Liu, D, Wang, J, Yang, X, Xue, L, Diao, T, Liu, J, Li, A, Zhang, B, Li, Z, Farrar, C A, Banda, N K, Bayarri-olmos, R, Garred, P, Zhou, W & Li, K 2021, ' Protective Role of Collectin 11 in a Mouse Model of Rheumatoid Arthritis ', Arthritis and Rheumatology, vol. 73, no. 8, pp. 1430-1440 . https://doi.org/10.1002/art.41696
Objective: Collectin 11 (CL-11) is a soluble C-type lectin, a mediator of innate immunity. Its role in autoimmune disorders is unknown. We undertook this study to determine the role of CL-11 in a mouse model of rheumatoid arthritis (RA). Methods: A m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fea9e9ad849ed40dc058b9cf42746c85
https://curis.ku.dk/portal/da/publications/protective-role-of-collectin-11-in-a-mouse-model-of-rheumatoid-arthritis(7db555d1-70d0-4c84-a9c7-305f761d2824).html
https://curis.ku.dk/portal/da/publications/protective-role-of-collectin-11-in-a-mouse-model-of-rheumatoid-arthritis(7db555d1-70d0-4c84-a9c7-305f761d2824).html
Autor:
Jia-Xing Wang, Kun-Yi Wu, Shu-Juan Zhao, Ke Li, Liang Bai, Enqi Liu, Daxin Chen, Teng-Yue Diao, Zongfang Li, Ning Ma, Wuding Zhou, Lin-Lin Wei
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 40(9)
Objective: Emerging evidence suggests that C3aR (C3a anaphylatoxin receptor) signaling has protective roles in various inflammatory-related diseases. However, its role in atherosclerosis has been unknown. The purpose of the study was to investigate t
Publikováno v:
JCI Insight
C5a is a potent inflammatory mediator that binds C5aR1 and C5aR2. Although pathogenic roles of the C5a/C5aR1 axis in inflammatory disorders are well documented, the roles for the C5a/C5aR2 axis in inflammatory disorders and underlying mechanisms rema
Autor:
Wuding Zhou, Kam Wa Chan, Sydney C.W. Tang, Kar Neng Lai, Wai Han Yiu, Rui Xi Li, Joseph Leung, Dickson W. L. Wong, Loretta Y.Y. Chan, Haojia Wu, Steven H. Sacks
Publikováno v:
Nephrology Dialysis Transplantation. 33:1323-1332
Background Complement C5 mediates pro-inflammatory responses in many immune-related renal diseases. Given that the C5a level is elevated in diabetes, we investigated whether activation of C5a/C5aR signalling plays a pathogenic role in diabetic nephro