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The encephalomyocarditis virus Leader promotes the release of virions inside extracellular vesicles via the induction of secretory autophagy

Autor: van der Grein, Susanne G, Defourny, Kyra A Y, Rabouw, Huib H, Goerdayal, Soenita S, van Herwijnen, Martijn J C, Wubbolts, Richard W, Altelaar, Maarten, van Kuppeveld, Frank J M, Nolte-'t Hoen, Esther N M, Virologie, Celbiologie, Afd Biomol.Mass Spect. and Proteomics, Biomolecular Mass Spectrometry and Proteomics, Bijvoet Centre for Biomolecular Research, IOV CCB

Publikováno v: Nature Communications, 13(1), 1. Nature Publishing Group

Naked viruses can escape host cells before the induction of lysis via release in extracellular vesicles (EVs). These nanosized EVs cloak the secreted virus particles in a host-derived membrane, which alters virus-host interactions that affect infecti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::715dc8fabcbab2da9136d6074e7e4801
https://dspace.library.uu.nl/handle/1874/421357

Retinyl esters form lipid droplets independently of triacylglycerol and seipin

Autor: Molenaar, Martijn R, Yadav, Kamlesh K, Toulmay, Alexandre, Wassenaar, Tsjerk A, Mari, Muriel C, Caillon, Lucie, Chorlay, Aymeric, Lukmantara, Ivan E, Haaker, Maya W, Wubbolts, Richard W, Houweling, Martin, Vaandrager, Arie Bas, Prieur, Xavier, Reggiori, Fulvio, Choudhary, Vineet, Yang, Hongyuan, Schneiter, Roger, Thiam, Abdou Rachid, Prinz, William A, Helms, J Bernd, dB&C FR-RMSC RMSC, Dep Scheikunde, Sub Biochemistry of Membranes begr1-6-12, Veterinaire biochemie, Celbiologie, IOV CCB, dB&C I&I, dB&C FR-RMSC FR

Publikováno v: The Journal of Cell Biology, 220(10):202011071. ROCKEFELLER UNIV PRESS
Journal of Cell Biology
Journal of Cell Biology, 2021, 220 (10), ⟨10.1083/jcb.202011071⟩
Journal of Cell Biology, Rockefeller University Press, 2021, 220 (10), ⟨10.1083/jcb.202011071⟩
The Journal of Cell Biology
Journal of Cell Biology, 220(10), 1. Rockefeller University Press

Molenaar et al. show that seipin does not play a role in the biogenesis of lipid droplets composed mostly or only of the neutral lipid retinyl ester, even in cells that produce triacylglycerols.
Lipid droplets store neutral lipids, primarily tri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a5918303642e99ebc5e72abdf8777cb
https://dspace.library.uu.nl/handle/1874/412830

Tissue Microarrays to Visualize Influenza D Attachment to Host Receptors in the Respiratory Tract of Farm Animals

Autor: Nemanichvili, Nikoloz, Berends, Alinda J, Wubbolts, Richard W, Gröne, Andrea, Rijks, Jolianne M, de Vries, Robert P, Verheije, Monique H, VP pathologie, dI&I I&I-1, dPB I&I, Celbiologie, IOV CCB, dB&C I&I, dPB CR, VPDC pathologie, Afd Chemical Biology and Drug Discovery, Pharmacology, Chemical Biology and Drug Discovery

Publikováno v: Viruses
Volume 13
Issue 4
Viruses, 13(4), 1. Multidisciplinary Digital Publishing Institute (MDPI)
Viruses, Vol 13, Iss 586, p 586 (2021)

The trimeric hemagglutinin-esterase fusion protein (HEF) of influenza D virus (IDV) binds 9-O-acetylated sialic acid receptors, which are expressed in various host species. While cattle are the main reservoir for IDV, the viral genome has also been d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d48b5c2433280efdd2a83da43ff6c13c
https://dspace.library.uu.nl/handle/1874/411840

MUC1 is a receptor for the Salmonella SiiE adhesin that enables apical invasion into enterocytes

Autor: Li, Xinyue, Bleumink-Pluym, Nancy M. C., Luijkx, Yvette M. C. A., Wubbolts, Richard W., van Putten, Jos P. M., Strijbis, Karin, dI&I I&I-2, LS Infectiebiologie (Bacteriologie), Faculteit Diergeneeskunde, dB&C I&I, LS Celbiologie-Algemeen, Sub Center for Cell Imaging, Afd Chemical Biology and Drug Discovery

Publikováno v: PLoS Pathogens, 15(2). Public Library of Science
PLoS Pathogens, Vol 15, Iss 2, p e1007566 (2019)
PLoS Pathogens

The cellular invasion machinery of the enteric pathogen Salmonella consists of a type III secretion system (T3SS) with injectable virulence factors that induce uptake by macropinocytosis. Salmonella invasion at the apical surface of intestinal epithe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52c779b3568aa850821049d51a1bbc65
https://dspace.library.uu.nl/handle/1874/377973