Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Wuan-Ting Saw"'
Autor:
Suhaili Mustafa, Noraini Abd-Aziz, Wuan-Ting Saw, Sien-Yei Liew, Khatijah Yusoff, Norazizah Shafee
Publikováno v:
Vaccines, Vol 8, Iss 4, p 742 (2020)
Enterovirus 71 (EV71) is the major causative agent in hand, foot, and mouth disease (HFMD), and it mainly infects children worldwide. Despite the risk, there is no effective vaccine available for this disease. Hence, a recombinant protein construct o
Externí odkaz:
https://doaj.org/article/df59efafbea94ae291624dd480cc780e
Autor:
Sarivin Vanan, Xiaoxia Zeng, Sook Yoong Chia, Katarina Varnäs, Mei Jiang, Ke Zhang, Wuan Ting Saw, Parasuraman Padmanabhan, Wei-Ping Yu, Zhi-Dong Zhou, Christer Halldin, Balázs Gulyás, Eng-King Tan, Li Zeng
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-15 (2020)
Abstract Vacuolar protein sorting 35 (VPS35) is a major component of the retromer complex that mediates the retrograde transport of cargo proteins from endosomes to the trans-Golgi network. Mutations such as D620N in the VPS35 gene have been identifi
Externí odkaz:
https://doaj.org/article/85c535b2d2c24c6982aab9b8d5a79aef
Autor:
Zhi Dong Zhou, Wuan Ting Saw, Patrick Ghim Hoe Ho, Zhi Wei Zhang, Li Zeng, Ya Yin Chang, Alfred Xu Yang Sun, Dong Rui Ma, Hong Yan Wang, Lei Zhou, Kah Leong Lim, Eng-King Tan
Publikováno v:
Cellular and Molecular Life Sciences. 79
Background Parkinson’s disease (PD) is characterized by selective and progressive dopamine (DA) neuron loss in the substantia nigra and other brain regions, with the presence of Lewy body formation. Most PD cases are sporadic, whereas monogenic for
Autor:
Zhi-Wei, Zhang, Haitao, Tu, Mei, Jiang, Sarivin, Vanan, Sook Yoong, Chia, Se-Eun, Jang, Wuan-Ting, Saw, Zhi-Wei, Ong, Dong-Rui, Ma, Zhi-Dong, Zhou, Jie, Xu, Kai-Hua, Guo, Wei-Ping, Yu, Shuo-Chien, Ling, Richard A, Margolin, Daniel G, Chain, Li, Zeng, Eng-King, Tan
Publikováno v:
Science signaling. 15(748)
Gain-of-function mutations in the leucine-rich repeat kinase 2 (
Autor:
Zhi Dong Zhou, Li Zeng, Christer Halldin, Wuan Ting Saw, Balázs Gulyás, Wei-Ping Yu, Katarina Varnäs, Xiaoxia Zeng, Ke Zhang, Sarivin Vanan, Mei Jiang, Sook Yoong Chia, Eng-King Tan, Parasuraman Padmanabhan
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-15 (2020)
Molecular Brain
Molecular Brain
Vacuolar protein sorting 35 (VPS35) is a major component of the retromer complex that mediates the retrograde transport of cargo proteins from endosomes to the trans-Golgi network. Mutations such as D620N in the VPS35 gene have been identified in pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51a5683147e6ca1e1fb37c9f7a117f4a
https://doi.org/10.21203/rs.3.rs-51781/v3
https://doi.org/10.21203/rs.3.rs-51781/v3
Autor:
Kah-Leong Lim, Bin Xiao, Zhi Dong Zhou, Xiao Deng, Wei Zhou, Eng-King Tan, Wuan-Ting Saw, Grace Lim
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1864:1308-1317
Parkin/PINK1-mediated mitophagy is implicated in the pathogenesis of Parkinson's disease (PD). Prior to elimination of damaged mitochondria, Parkin translocates to mitochondria and induces mitochondrial clustering. While the mechanism of PINK1-depend
Publikováno v:
Molecular neurobiology. 54(7)
Autor:
Hongyan Wang, Zhi Dong Zhou, Wuan Ting Saw, Shao Ping Xie, Patrick Ho, Lei Zhou, Eng-King Tan, Yi Zhao
Publikováno v:
Cells, Vol 8, Iss 8, p 911 (2019)
Cells
Volume 8
Issue 8
Cells
Volume 8
Issue 8
Accumulative evidence indicated that the pathologically accumulated metal ions (iron species and Mn3+) and abnormally up-regulated monoamine oxidase B (MAOB) activity induced oxidation of endogenous dopamine (DA) can lead to mitochondria impairment,
Publikováno v:
Molecular neurobiology. 54(7)
The coiled-coil-helix-coiled-coil-helix domain (CHCHD)-containing proteins are evolutionarily conserved nucleus-encoded small mitochondrial proteins with important functions. So far, nine members have been identified in this protein family. All CHCHD
Autor:
Sushmitha Sathiyamoorthy, Heidi Pek Hup Chua, Eng-King Tan, Zeng Li, Hongyan Wang, Tit Meng Lim, Tan Ye Sing, Dario C. Angeles, Alyssa Mei Yan Tang, Mitchell K.P. Lai, Shao Ping Xie, Zhi Dong Zhou, Fathima Shaffra, Patrick Ho, Wuan Ting Saw, Shin Hui Ng
Publikováno v:
Human molecular genetics. 24(22)
The mutations of F-box protein 7 (FBXO7) gene (T22M, R378G and R498X) are associated with a severe form of autosomal recessive juvenile-onset Parkinson's disease (PD) (PARK 15). Here we demonstrated that wild-type (WT) FBXO7 is a stress response prot