Multi-structural molecular docking (MOD) combined with molecular dynamics reveal the structural requirements of designing broad-spectrum inhibitors of SARS-CoV-2 entry to host cells.

Autor: Da A; Institute of Pharmaceutical Science, King's College London, London, UK., Wu-Lu M; Institute of Chemistry, Technische Universität Berlin, Berlin, Germany., Dragelj J; Institute of Chemistry, Technische Universität Berlin, Berlin, Germany., Mroginski MA; Institute of Chemistry, Technische Universität Berlin, Berlin, Germany. andrea.mroginski@tu-berlin.de., Ebrahimi KH; Institute of Pharmaceutical Science, King's College London, London, UK. Kourosh.Ebrahimi@kcl.ac.uk.

Publikováno v: Scientific reports [Sci Rep] 2023 Sep 29; Vol. 13 (1), pp. 16387. Date of Electronic Publication: 2023 Sep 29.

Computational identification of PDL1 inhibitors and their cytotoxic effects with silver and gold nanoparticles.

Autor: Ali, Syed Hammad¹ (AUTHOR), Ali, Hiba² (AUTHOR), Aziz, Mohd. Azhar^1,3 (AUTHOR) azhar.inc@amu.ac.in

Publikováno v: Scientific Reports. 11/4/2024, Vol. 14 Issue 1, p1-20. 20p.

Labyrinth and Piano Key Weirs II

Autor: Sébastien Erpicum, Frédéric Laugier, Michael Pfister, Michel Pirotton, Guy-Michel Cicero, Anton J. Schleiss

Dam engineering is currently experiencing a strong revival of labyrinth oriented weirs. Labyrinth weirs, with a repetitive constructional character and an increased specific discharge capacity, are a very good technical-economical compromise. The con