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Akademický článek

Galangin mitigates glucocorticoid-induced osteoporosis by activating autophagy of BMSCs via triggering the PKA/CREB signaling pathway

Autor: Zeng Chenying, Wang Shan, Gu Huimin, Chen Fenglei, Wang Ziming, Li Jinteng, Xie Zhongyu, Feng Pei, Shen Huiyong, Wu Yanfeng

Publikováno v: Acta Biochimica et Biophysica Sinica, Vol 55, Pp 1275-1287 (2023)

Glucocorticoid-induced osteoporosis (GIOP), one of the most common and serious adverse effects associated with glucocorticoid administration, manifests as decreased bone formation and increased bone resorption, eventually culminating in bone loss. Ga

Externí odkaz: https://doaj.org/article/86a3670ba62e47519ede5c4467435a7b

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Akademický článek

BMAL1-TTK-H2Bub1 loop deficiency contributes to impaired BM-MSC-mediated bone formation in senile osteoporosis

Autor: Li Jinteng, Xu Peitao, Yu Wenhui, Ye Guiwen, Ye Feng, Xu Xiaojun, Su Zepeng, Lin Jiajie, Che Yunshu, Zhang Zhaoqiang, Zeng Yipeng, Li Zhikun, Feng Pei, Cao Qian, Li Dateng, Xie Zhongyu, Wu Yanfeng, Shen Huiyong

Publikováno v: Molecular Therapy: Nucleic Acids, Vol 31, Iss , Pp 568-585 (2023)

During the aging process, the reduced osteogenic differentiation of bone marrow mesenchymal stem cells (BM-MSCs) results in decreased bone formation, which contributes to senile osteoporosis. Previous studies have confirmed that interrupted circadian

Externí odkaz: https://doaj.org/article/57b2ce42a4f34cabb650fd41c113b427

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Akademický článek

Association of post-stroke shoulder pain and MRI features

Autor: ZHU Mingyue, WU Yanfeng, LI Yige, WANG Luoluo, LI Lin, TAO Shuwei, LIU Yuanbiao

Publikováno v: Zhongguo linchuang yanjiu, Vol 36, Iss 8, Pp 1228-1231，1237 (2023)

ObjectiveTo explore the features of magnetic resonance imaging （MRI） on post-stroke shoulder pain （PSSP） and the influencing factors of PSSP, in order to provide a basis for precise treatment of PSSP. MethodsA total of 83 PSSP patients were s

Externí odkaz: https://doaj.org/article/52ed820a8d1d4a45839072bbcc3ef50e

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Akademický článek

Variations in the Gut Microbiota in Breast Cancer Occurrence and Bone Metastasis

Autor: Yu Wenhui, Xie Zhongyu, Chen Kai, Cai Zhaopeng, Li Jinteng, Ma Mengjun, Su Zepeng, Che Yunshu, Wang Peng, Wu Yanfeng, Shen Huiyong

Publikováno v: Frontiers in Microbiology, Vol 13 (2022)

Breast cancer is the most common cancer in women and the second most common cancer overall. Although advancements in the early diagnosis and therapy of breast cancer have occurred in recent years, the prognosis of breast cancer bone metastasis remain

Externí odkaz: https://doaj.org/article/eb25744a3420436eb0461d018e0d3723

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