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The minor allele of the CREBRF rs373863828 p.R457Q coding variant is associated with reduced levels of myostatin in males: Implications for body composition.

Autor: Lee K; Maurice Wilkins Centre for Molecular Biodiscovery, The University of Auckland, Auckland, New Zealand; Department of Molecular Medicine and Pathology, School of Medical Sciences, The University of Auckland, Auckland, New Zealand., Vakili S; Maurice Wilkins Centre for Molecular Biodiscovery, The University of Auckland, Auckland, New Zealand; Department of Molecular Medicine and Pathology, School of Medical Sciences, The University of Auckland, Auckland, New Zealand., Burden HJ; Maurice Wilkins Centre for Molecular Biodiscovery, The University of Auckland, Auckland, New Zealand; Department of Molecular Medicine and Pathology, School of Medical Sciences, The University of Auckland, Auckland, New Zealand., Adams S; Discipline of Nutrition, School of Medical Sciences, The University of Auckland, Auckland, New Zealand., Smith GC; Department of Pharmacology, School of Medical Sciences, UNSW Australia, Kensington, Australia., Kulatea B; Discipline of Nutrition, School of Medical Sciences, The University of Auckland, Auckland, New Zealand., Wright-McNaughton M; Department of Medicine, University of Otago Wellington, Wellington, New Zealand., Sword D; Department of Medicine, University of Otago Wellington, Wellington, New Zealand., Watene-O'Sullivan C; Moko Foundation and Waharoa Ki Te Toi Research Centre, Kaitaia, New Zealand., Atiola RD; Discipline of Nutrition, School of Medical Sciences, The University of Auckland, Auckland, New Zealand., Paul RG; Waikato Medical Research Centre, University of Waikato, Hamilton, New Zealand., Plank LD; Department of Surgery, School of Medicine, The University of Auckland, Auckland, New Zealand., Kallingappa P; Department of Molecular Medicine and Pathology, School of Medical Sciences, The University of Auckland, Auckland, New Zealand., King F; Ngati Porou Hauora, Te Puia Springs, New Zealand., Wilcox P; Department of Mathematics and Statistics, University of Otago, New Zealand., Merriman TR; Maurice Wilkins Centre for Molecular Biodiscovery, The University of Auckland, Auckland, New Zealand; Department of Biochemistry, School of Biomedical Sciences, University of Otago, New Zealand; Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Alabama, United States., Krebs JD; Maurice Wilkins Centre for Molecular Biodiscovery, The University of Auckland, Auckland, New Zealand; Department of Medicine, University of Otago Wellington, Wellington, New Zealand., Hall RM; Maurice Wilkins Centre for Molecular Biodiscovery, The University of Auckland, Auckland, New Zealand; Department of Medicine, University of Otago Wellington, Wellington, New Zealand., Murphy R; Maurice Wilkins Centre for Molecular Biodiscovery, The University of Auckland, Auckland, New Zealand; Department of Medicine, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand., Merry TL; Discipline of Nutrition, School of Medical Sciences, The University of Auckland, Auckland, New Zealand; Maurice Wilkins Centre for Molecular Biodiscovery, The University of Auckland, Auckland, New Zealand., Shepherd PR; Maurice Wilkins Centre for Molecular Biodiscovery, The University of Auckland, Auckland, New Zealand; Department of Molecular Medicine and Pathology, School of Medical Sciences, The University of Auckland, Auckland, New Zealand. Electronic address: peter.shepherd@auckland.ac.nz.

Publikováno v: Molecular metabolism [Mol Metab] 2022 May; Vol. 59, pp. 101464. Date of Electronic Publication: 2022 Feb 24.