Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Wren Douglas L"'
Autor:
Horn Albert R Van, Tsung T. Li, David Y. Jackson, Edvige Galeazzi, Cooper Gary F, Wren Douglas L, Colin C. Beard
Publikováno v:
The Journal of Organic Chemistry. 58:4280-4286
The four stereoisomeric components of enprostil (1a-d) were prepared using an orthoester Claisen rearrangement of individual propargylic alcohol intermediates 8 to generate the required allene upper chain stereochemistry, followed by one-carbon homol
Publikováno v:
ChemInform. 22
Autor:
G. F. Cooper, Wren Douglas L, A. R. Van Horn, Edvige Galeazzi, Li Tsung-Tee, Colin C. Beard, David Y. Jackson
Publikováno v:
ChemInform. 24
Publikováno v:
The Journal of Organic Chemistry. 56:1083-1088
We have described a highly enantioselective synthesis of the title allenic alcohols in multigram quantities. Either enantiomer is now available in >94% ee through a single intermediate of known absolute configuration. A 13 C NMR based analytical meth
Publikováno v:
Steroids. 56:8-11
A convenient synthesis of both 5 beta,17 alpha-19-norpregn-20-yne-3 beta,17-diol (1) and 5 beta,17 alpha-19-norpregn-20-yne-3 alpha,17-diol (2) in multigram quantities from estr-4-ene-3,17-dione is reported. Full characterization of these often-cited
Autor:
Cooper, Gary F., Wren, Douglas L.
Publikováno v:
Journal of Organic Chemistry; 7/30/93, Vol. 58 Issue 16, p4280, 7p, 5 Diagrams
Publikováno v:
Synthetic Communications. 13:225-231
The transformation of 4-bromo-2-(2′-acetoxyethyl) cyclopenten-1-one, 2, into hydroxenone 3, has been investigated. Silver oxide was determined to be the reagent of choice.
Autor:
Gabriel Garay, A.Peter Roszkowski, Angel Guzman, Humberto Carpio, J.A. Mendez, Joseph M. Muchowski, Wren Douglas L, John H Fried, Horn Albert R Van, John A Edwards, Gary F. Cooper
Publikováno v:
Prostaglandins. 33:169-180
In order to improve the modest oral activity of PGE 2 as an inhibitor of gastric acid secretion, analogs were prepared and tested orally in histamine-challenged rats. Insertion of a double bond at C-4, resulting in the 4,5-allene analog of PGE 1 , ga
Autor:
Fidencio Franco, Joseph M. Muchowski, Virginia Perez, Angel Guzman, A. R. Van Horn, Anthony Prince, Humberto Carpio, R. Koehler, Michael L. Maddox, Wren Douglas L, Y. Antonio, D. Valdes, D. Cho, R. Salas, O. Halpern, J. Ackrell, P. Gallegra, Esperanza Velarde, Edvige Galeazzi, T. C. Thurber, Derek Tegg, Robert Greenhouse, A. Leon
Publikováno v:
Chemischer Informationsdienst. 14